Patents Assigned to Sagami Chemical Research Center
  • Publication number: 20090018345
    Abstract: Disclosed are pyrazole-1-carboxylate derivatives of the general formula (1), (wherein symbols are as defined in the specification), a process for the production thereof and processes for producing herbicidally active 3-aryloxypyrazole-1-carboxamide derivatives from the above compound and an intermediate therefor. According to this invention, there can be industrially advantageously produced 3-aryloxypyrazole-1-carboxamide derivatives that does not cause chemical damage on crops but exhibits excellent herbicidal activity against weeds that impair the growth of such crops.
    Type: Application
    Filed: May 22, 2006
    Publication date: January 15, 2009
    Applicants: KAKEN PHARMACEUTICAL CO., LTD., SAGAMI CHEMICAL RESEARCH CENTER
    Inventors: Atsushi Uchida, Wakako Yokota, Kenji Hirai, Tomoyuki Yano
  • Patent number: 7470808
    Abstract: A process for producing a fluorine-containing acrylic acid ester represented by CH2?C(Rf)(COOR) characterized in that 1-bromo-1-perfluoroalkylethene represented by CH2?CBr—Rf, or 1,2-dibromo-1-perfluoroalkylethane represented by CH2CBr—CHBr—Rf is allowed to react with an alcohol represented by ROH in the presence of a palladium catalyst, carbon monoxide, and two or more kinds of bases. The fluorine-containing acrylic acid ester is a useful compound having wide applications in materials for pharmaceuticals and functional polymers.
    Type: Grant
    Filed: March 24, 2004
    Date of Patent: December 30, 2008
    Assignees: Tosoh F-Tech, Inc., Sagami Chemical Research Center
    Inventors: Takamasa Fuchikami, Noriko Wakasa, Kenji Tokuhisa, Hideyuki Mimura, Shoji Arai
  • Patent number: 7265233
    Abstract: An organometallic iridium compound having low melting point, excellent vaporization characteristic and low film formation temperature on a substrate, a process for producing the compound, and a process for preparing iridium-based films using the organometallic compound are provided. The organometallic iridium compound represented by the formula (1) (example of specific compound: (ethylcyclopentadienyl)bis(ethylene)iridium) is obtained by reacting a compound represented by the formula (4) with a compound represented by the formula (2) or (3) An iridium-based film is prepared using the compound as a precursor. In the formulae, R1 represents hydrogen atom or a lower alkyl group; R2 represents a lower alkyl group; X represents a halogen atom; and M represents an alkali metal.
    Type: Grant
    Filed: August 11, 2004
    Date of Patent: September 4, 2007
    Assignees: Tosoh Corporation, Sagami Chemical Research Center
    Inventors: Kazuhisa Kawano, Mayumi Takamori, Noriaki Oshima
  • Publication number: 20050074842
    Abstract: Proteins comprising any of the amino acid sequences of SEQ ID NOS: 1 to 18 and DNAs encoding said proteins and comprising any of the nucelotide sequences of SEQ ID NOS: 19 to 36 are provided.
    Type: Application
    Filed: July 25, 2003
    Publication date: April 7, 2005
    Applicants: Sagami Chemical Research Center, Protegene Inc.
    Inventors: Seishi Kato, Shingo Sekine, Tomoko Kimura
  • Patent number: 6808766
    Abstract: A liquid crystal alignment agent comprising a polymer having a specific unit structure, and a method for alignment of liquid crystal molecules by light irradiation without any rubbing treatment, provides liquid crystal alignment films with higher heat sensitivity, heat stability and light resistance.
    Type: Grant
    Filed: February 21, 2001
    Date of Patent: October 26, 2004
    Assignees: Nissan Chemical Industries, Ltd., Sagami Chemical Research Center
    Inventors: Yukihiro Miyama, Takayasu Nihira, Hideyuki Endo, Hiroyoshi Fukuro, Yu Nagase, Eiich Akiyama, Nobukatsu Nemoto
  • Patent number: 6797832
    Abstract: The present invention provides a method of producing 5-oxy-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ester economically, industrially advantageously and efficiently in a large amount. The present invention is a method of producing 5-oxy-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ester (X), which is shown in the following scheme. wherein each symbol is as defined in the specification.
    Type: Grant
    Filed: June 21, 2002
    Date of Patent: September 28, 2004
    Assignees: Sagami Chemical Research Center, Kuraray Co., Ltd.
    Inventors: Shiro Terashima, Katsuji Ujita, Tomoya Kuwayama, Takashi Sugioka, Kazuya Shimizu, Koichi Kanehira
  • Patent number: 6790964
    Abstract: The present invention provides a method of producing 7-azabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ester (VII) economically, industrially advantageously and efficiently in a large amount.
    Type: Grant
    Filed: August 13, 2002
    Date of Patent: September 14, 2004
    Assignees: Sagami Chemical Research Center, Kuraray Co., Ltd.
    Inventors: Shiro Terashima, Katsuji Ujita, Akihiro Ishiwata
  • Publication number: 20040068104
    Abstract: Cloning of human cDNAs coding for galectin-9-like proteins, expression with Escherichia coli of proteins encoded by these human cDNAs, and determination of the lactose-binding activity of these expression products.
    Type: Application
    Filed: August 4, 2003
    Publication date: April 8, 2004
    Applicants: Sagami Chemical Research Center, Protegene Inc.
    Inventors: Seishi Kato, Tomoko Kimura, Shingo Sekine, Kouju Kamata
  • Publication number: 20040048339
    Abstract: The invention provides human proteins having transmembrane domains and cDNAs coding for these proteins as well as eucaryotic cells expressing said cDNAs. All of the proteins exist in the cell membrane, so that they are considered to be proteins controlling the proliferation and the differentiation of the cells. Accordingly, the proteins can be employed as pharmaceuticals such as carcinostatic agents relating to the control of the proliferation and the differentiation of the cells or as antigens for preparing antibodies against said proteins. The cDNAs can be utilized as probes for the gene diagnosis and gene sources for the gene therapy. Furthermore, the cDNAs can be utilized for large-scale expression of said proteins. Cells, wherein these membrane protein genes are introduced and membrane proteins are expressed in large amounts, can be utilized for detection of the corresponding ligands, screening of novel low-molecular pharmaceuticals, and so on.
    Type: Application
    Filed: July 11, 2003
    Publication date: March 11, 2004
    Applicants: Sagami Chemical Research Center, Protegene, Inc.
    Inventors: Seishi Kato, Shingo Sekine
  • Patent number: 6703201
    Abstract: The present invention provides a human PEC-60-like protein, a gastrointestinal hormone excreted by a stomach tissue and a cDNA encoding this protein. The protein and the gene of the present invention can provide a protein containing the amino acid sequence represented by Sequence No. 1 and a DNA encoding said protein exemplified as a cDNA containing the base sequence represented by Sequence No. 1 as well as a human cDNA encoding a human PEC-60-like protein and said protein by the expression of this human cDNA recombinant.
    Type: Grant
    Filed: September 27, 2000
    Date of Patent: March 9, 2004
    Assignee: Sagami Chemical Research Center
    Inventors: Seishi Kato, Tomoko Yamaguchi, Shingo Sekine, Kouju Kamata
  • Patent number: 6677464
    Abstract: The present invention provides a method of industrially advantageously producing 7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid derivatives under mild conditions in a high yield. The present invention relates to a production method of a 7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid derivative of the formula (III) or the formula (IV), which comprises reacting an &agr;,&bgr;-unsaturated carboxylic acid of the formula (I) with a furan derivative of the formula (II) in the presence of a Lewis acid: wherein each symbol is as defined in the specification.
    Type: Grant
    Filed: March 14, 2003
    Date of Patent: January 13, 2004
    Assignees: Kuraray Co., Ltd., Sagami Chemical Research Center
    Inventors: Tomoya Kuwayama, Katsuji Ujita, Kazuya Shimizu, Shiro Terashima
  • Patent number: 6589977
    Abstract: Bisindolylpyrrole derivatives represented by general formula [I] which are useful in inhibiting cell death and expected as being useful as preventives and remedies for the progress of various diseases in the progress and worsening of which cell death participates; and cell death inhibitors, drugs and cell/tissue/organ preservatives containing as the active ingredient these derivatives or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: August 6, 2001
    Date of Patent: July 8, 2003
    Assignees: Sagami Chemical Research Center
    Inventors: Mikiko Sodeoka, Miho Katoh, Mikako Fujita, Rei Asakai
  • Patent number: 6548511
    Abstract: This invention provides an insecticidal and acaricidal agent which can control various insanitary insects and insects, mites and eggs thereof which are harmful to the agricultural and horticultural products, at a low chemical concentration. The insecticidal and acaricidal agent of this invention contains an anilinopyrimidinone derivative represented by the following general formula (I) as an active ingredient.
    Type: Grant
    Filed: February 9, 2000
    Date of Patent: April 15, 2003
    Assignees: Sagami Chemical Research Center, Mitsubishi Chemical Corporation
    Inventors: Kenji Hirai, Takeshi Yoshizawa, Sachiko Itoh, Natsuko Okano, Yuriko Nagata, Chikako Ota, Toshiki Fukuchi, Keiko Yoshiya
  • Patent number: 6500939
    Abstract: The invention provides cDNAs coding for human proteins having transmembrane domains and eucaryotic cells expressing said cDNAs. The cDNAs of the invention can be utilized as probes for the gene diagnosis and gene sources for the gene therapy. Furthermore, the cDNAs can be utilized for large-scale expression of said proteins. Cells, wherein these membrane protein genes are introduced and membrane proteins are expressed in large amounts, can be utilized for detection of the corresponding ligands, screening of novel low-molecular pharmaceuticals, and so on.
    Type: Grant
    Filed: August 21, 2000
    Date of Patent: December 31, 2002
    Assignees: Sagami Chemical Research Center, Protogene, Inc.
    Inventors: Seishi Kato, Shingo Sekine
  • Patent number: 6476267
    Abstract: A method for producing an aromatic primary amine, characterized by hydrogenating an aromatic nitrile at a low partial pressure of hydrogen in a heterogeneous system comprising a non-reductive polar solvent and a nickel-immobilized catalyst suspended therein was proposed. By such method, an aromatic primary amine which is industrially useful as a medicine, agricultural chemical, dye surfactant, chemical agent, etc. can be produced in a high yield.
    Type: Grant
    Filed: November 19, 2001
    Date of Patent: November 5, 2002
    Assignee: Sagami Chemical Research Center
    Inventors: Takamasa Fuchigami, Satoshi Takamizawa, Noriko Wakasa
  • Publication number: 20020106777
    Abstract: The present invention provides a human PEC-60-like protein, a gastrointestinal hormone excreted by a stomach tissue and a cDNA encoding this protein. The protein and the gene of the present invention can provide a protein containing the amino acid sequence represented by Sequence No. 1 and a t DNA encoding said protein exemplified as a cDNA containing the base sequence represented by Sequence No. 1. as well as a human cDNA encoding a human PEC-60-like protein and said protein by the expression of this human cDNA recombinant.
    Type: Application
    Filed: August 28, 2001
    Publication date: August 8, 2002
    Applicant: Sagami Chemical Research Center
    Inventors: Seishi Kato, Tomoko Yamaguchi, Shingo Sekine, Kouju Kamata
  • Patent number: 6280968
    Abstract: The present invention provides a human PEC-60-like protein, a gastrointestinal hormone excreted by a stomach tissue and a cDNA encoding this protein. The protein and the gene of the present invention can provide a protein containing the amino acid sequence represented by Sequence No. 1 and a DNA encoding said protein exemplified as a cDNA containing the base sequence represented by Sequence No. 1. as well as a human cDNA encoding a human PEC-60-like protein and said protein by the expression of this human cDNA recombinant.
    Type: Grant
    Filed: April 17, 1998
    Date of Patent: August 28, 2001
    Assignee: Sagami Chemical Research Center
    Inventors: Seishi Kato, Tomoko Yamaguchi, Shingo Sekine, Kouju Kamata
  • Patent number: 6180602
    Abstract: Isolated cDNAs derived from mRNAs expressed in human cells are provided, as are DNAs and RNAs comprising their nucleotide sequences, and vectors for expressing the cDNAs. The cDNAs encode proteins which have functions similar to known proteins.
    Type: Grant
    Filed: January 2, 1997
    Date of Patent: January 30, 2001
    Assignee: Sagami Chemical Research Center
    Inventors: Seishi Kato, Suwan Oh, Shingo Sekine, Mihoro Saeki, Midori Kobayashi, Mika Yada, Tomoko Tsuji, Hitoshi Ohmori
  • Patent number: 6100219
    Abstract: The present invention provides a plant growth promoter comprising an epoxycylohexane derivative represented by the general formula: ##STR1## (wherein by R.sup.1 represents a hydrogen atom, C1 to C6 alkyl group or C3 to C6 cycloalkyl group, and R.sup.2 and R.sup.3 are independently lower alkyl groups or are combined to form a polymethylene group which may be substituted with an alkyl group) and gibberellin as active ingredients.
    Type: Grant
    Filed: November 30, 1998
    Date of Patent: August 8, 2000
    Assignees: Sagami Chemical Research Center, Tama Biochemical Co., Ltd., Bal Planning Co., Ltd.
    Inventors: Kunikazu Sakai, Yasuo Kamuro, Hiroki Kuriyama
  • Patent number: 6090946
    Abstract: The present invention provides an industrial process for efficiently preparing a 3-(substituted phenyl)-5-isopropylidene-1,3-oxazolidine-2,4-dione derivative having a potent herbicidal activity without using phosgene or the like. The present invention relates to a process for preparing a 3-(substituted phenyl)-5-alkylidene-1,3-oxazolidine-2,4-dione derivative represented by general formula (III), which comprises reaction of an N-(substituted phenyl)carbamate represented by general formula (I) with a 2-hydroxy-3-alkenoate represented by-general formula (II) or with a 3-alkoxy-2-hydroxyalkanoate represented by general formula (IV): ##STR1## (wherein Ar is a substituted phenyl group, R.sup.1 is an alkyl group having a carbon number of from 1 to 6, R.sup.2 and R.sup.3 are independently hydrogen atoms or alkyl groups having carbon numbers of from 1 to 12, and R.sup.4 and R.sup.5 are independently alkyl groups having carbon numbers of from 1 to 6).
    Type: Grant
    Filed: December 15, 1997
    Date of Patent: July 18, 2000
    Assignees: Sagami Chemical Research Center, Kaken Pharmaceutical Co., Ltd
    Inventors: Kenji Hirai, Katsuyuki Masuda, Tomoyuki Yano, Ryuta Ohno, Tomoko Matsukawa, Kiyomi Imai, Natsuko Okano, Tomoko Yoshii, Takehito Mouri