Patents Assigned to Sage Pharmaceuticals, Inc.
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Patent number: 10548831Abstract: The present invention provides a novel anhydrous composition of small-molecule polysaccharides, consisting of at least a small-molecule polysaccharide and an anhydrous base. The formulation of the anhydrous composition of small-molecule polysaccharides allows the small-molecule polysaccharide to maintain a molecular size of 12-22 nm and the direct penetration of the small-molecule polysaccharide across the horny layer of skin. The present invention also provides a method of effectively maintaining skin hydration level in a subject in need thereof, comprising topically administering to the subject an anhydrous composition of small-molecule polysaccharides.Type: GrantFiled: May 9, 2016Date of Patent: February 4, 2020Assignee: SAGE PHARMACEUTICALS, INC.Inventor: Tsung-Yu Ou
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Patent number: 7094426Abstract: The present invention relates to new stable enteric coated pharmaceutical dosage forms for oral use containing Omeprazole or Lansoprazole, to a formulation and a method for the manufacture of such a dosage forms, and to a method of gastric acid pump inhibition and providing gastrointestinal cytoprotective benefit by using them.Type: GrantFiled: April 26, 2004Date of Patent: August 22, 2006Assignee: Sage Pharmaceuticals, Inc.Inventor: Jivn-Ren Chen
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Patent number: 7041316Abstract: The present invention relates to new stable enteric coated pharmaceutical dosage forms for oral use containing Omeprazole or Lansoprazole, to a formulation and a method for the manufacture of such a dosage forms, and to a method of gastric acid pump inhibition and providing gastrointestinal cytoprotective benefit by using them.Type: GrantFiled: April 24, 2003Date of Patent: May 9, 2006Assignee: Sage Pharmaceuticals, Inc.Inventor: Jivn-Ren Chen
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Patent number: 6987133Abstract: This invention relates to a topical spray preparation for burn treatment and microbial infections on human being or animals. This non-aerosol preparation contains an antimicrobial drug, i.e., silver sulfadiazine, as is dispersed or solubilized in a cream or lotion base matrix which can be sprayed directly from a common trigger spray device. The key component of the matrix can be characterized by it having a suitable molecular weight polymer of cross-linked acrylic acid, such as Carbomers or non-ionic surfactants such as polyoxyethylene alkyl ethers, or any combination of the above materials.Type: GrantFiled: April 1, 2003Date of Patent: January 17, 2006Assignee: Sage Pharmaceuticals, Inc.Inventor: Jivn-Ren Chen
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Publication number: 20040197394Abstract: The present invention relates to new stable enteric coated pharmaceutical dosage forms for oral use containing Omeprazole or Lansoprazole, to a formulation and a method for the manufacture of such a dosage forms, and to a method of gastric acid pump inhibition and providing gastrointestinal cytoprotective benefit by using them.Type: ApplicationFiled: April 26, 2004Publication date: October 7, 2004Applicant: Sage Pharmaceuticals, Inc.Inventor: Jivn-Ren Chen
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Patent number: 6726927Abstract: The present invention relates to new stable enteric coated pharmaceutical dosage forms for oral use containing Omeprazole or Lansoprazole, to a formulation and a method for the manufacture of such a dosage forms, and to a method of gastric acid pump inhibition and providing gastrointestinal cytoprotective benefit by using them.Type: GrantFiled: August 27, 1998Date of Patent: April 27, 2004Assignee: Sage Pharmaceuticals, Inc.Inventor: Jivn-Ren Chen
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Publication number: 20030203018Abstract: The present invention relates to new stable enteric coated pharmaceutical dosage forms for oral use containing Omeprazole or Lansoprazole, to a formulation and a method for the manufacture of such a dosage forms, and to a method of gastric acid pump inhibition and providing gastrointestinal cytoprotective benefit by using them.Type: ApplicationFiled: April 24, 2003Publication date: October 30, 2003Applicant: Sage Pharmaceuticals, Inc.Inventor: Jivn-Ren Chen
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Publication number: 20030170182Abstract: This invention relates to a topical spray preparation for burn treatment and microbial infections on human being or animals. This non-aerosol preparation contains an antimicrobial drug, i.e., silver sulfadiazine, as is dispersed or solubilized in a cream or lotion base matrix which can be sprayed directly from a common trigger spray device. The key component of the matrix can be characterized by it having a suitable molecular weight polymer of cross-linked acrylic acid, such as Carbomers or non-ionic surfactants such as polyoxyethylene alkyl ethers, or any combination of the above materials.Type: ApplicationFiled: April 1, 2003Publication date: September 11, 2003Applicant: Sage Pharmaceuticals, Inc.Inventor: Jivn-Ren Chen
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Patent number: 6551577Abstract: This invention relates to a topical spray preparation for burn treatment and microbial infections on human being or animals. This non-aerosol preparation contains an antimicrobial drug, i.e., silver sulfadiazine, as is dispersed or solubilized in a cream or lotion base matrix which can be sprayed directly from a common trigger spray device. The key component of the matrix can be characterized by it having a suitable molecular weight polymer of cross-linked acrylic acid, such as Carbomers or non-ionic surfactants such as polyoxyethylene alkyl ethers, or any combination of the above materials.Type: GrantFiled: June 23, 1999Date of Patent: April 22, 2003Assignee: Sage Pharmaceuticals, Inc.Inventor: Jivn-Ren Chen
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Patent number: 5191114Abstract: Direct compressible ibuprofen particles are formed by treating commercially available, dry ibuprofen with a hydrophilic solvent in one embodiment, a mixture of a hydrophilic solvent and one or more hydrophobic organic solvents in a second embodiment and one or more hydrophobic organic solvents in a third embodiment, to change at least the external crystalline shape of the ibuprofen from a flow-retarding shape to a free-flowing, easily compressible configuration. A typical hydrophilic solvent is water and among the hydrophobic solvents which may be used are acetone, methyl alcohol, ethyl alcohol, isopropyl and N-propyl alcohol. Direct compressible ibuprofen particles having superior flow characteristics may also be prepared by mixing commercially available, dry ibuprofen with micron size, amorphous silica gel in various formulations.Type: GrantFiled: October 9, 1991Date of Patent: March 2, 1993Assignee: Sage Pharmaceuticals, Inc.Inventor: Jivn-Ren Chen