Patents Assigned to Sage Pharmaceuticals, Inc.
  • Patent number: 10548831
    Abstract: The present invention provides a novel anhydrous composition of small-molecule polysaccharides, consisting of at least a small-molecule polysaccharide and an anhydrous base. The formulation of the anhydrous composition of small-molecule polysaccharides allows the small-molecule polysaccharide to maintain a molecular size of 12-22 nm and the direct penetration of the small-molecule polysaccharide across the horny layer of skin. The present invention also provides a method of effectively maintaining skin hydration level in a subject in need thereof, comprising topically administering to the subject an anhydrous composition of small-molecule polysaccharides.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: February 4, 2020
    Assignee: SAGE PHARMACEUTICALS, INC.
    Inventor: Tsung-Yu Ou
  • Patent number: 7094426
    Abstract: The present invention relates to new stable enteric coated pharmaceutical dosage forms for oral use containing Omeprazole or Lansoprazole, to a formulation and a method for the manufacture of such a dosage forms, and to a method of gastric acid pump inhibition and providing gastrointestinal cytoprotective benefit by using them.
    Type: Grant
    Filed: April 26, 2004
    Date of Patent: August 22, 2006
    Assignee: Sage Pharmaceuticals, Inc.
    Inventor: Jivn-Ren Chen
  • Patent number: 7041316
    Abstract: The present invention relates to new stable enteric coated pharmaceutical dosage forms for oral use containing Omeprazole or Lansoprazole, to a formulation and a method for the manufacture of such a dosage forms, and to a method of gastric acid pump inhibition and providing gastrointestinal cytoprotective benefit by using them.
    Type: Grant
    Filed: April 24, 2003
    Date of Patent: May 9, 2006
    Assignee: Sage Pharmaceuticals, Inc.
    Inventor: Jivn-Ren Chen
  • Patent number: 6987133
    Abstract: This invention relates to a topical spray preparation for burn treatment and microbial infections on human being or animals. This non-aerosol preparation contains an antimicrobial drug, i.e., silver sulfadiazine, as is dispersed or solubilized in a cream or lotion base matrix which can be sprayed directly from a common trigger spray device. The key component of the matrix can be characterized by it having a suitable molecular weight polymer of cross-linked acrylic acid, such as Carbomers or non-ionic surfactants such as polyoxyethylene alkyl ethers, or any combination of the above materials.
    Type: Grant
    Filed: April 1, 2003
    Date of Patent: January 17, 2006
    Assignee: Sage Pharmaceuticals, Inc.
    Inventor: Jivn-Ren Chen
  • Publication number: 20040197394
    Abstract: The present invention relates to new stable enteric coated pharmaceutical dosage forms for oral use containing Omeprazole or Lansoprazole, to a formulation and a method for the manufacture of such a dosage forms, and to a method of gastric acid pump inhibition and providing gastrointestinal cytoprotective benefit by using them.
    Type: Application
    Filed: April 26, 2004
    Publication date: October 7, 2004
    Applicant: Sage Pharmaceuticals, Inc.
    Inventor: Jivn-Ren Chen
  • Patent number: 6726927
    Abstract: The present invention relates to new stable enteric coated pharmaceutical dosage forms for oral use containing Omeprazole or Lansoprazole, to a formulation and a method for the manufacture of such a dosage forms, and to a method of gastric acid pump inhibition and providing gastrointestinal cytoprotective benefit by using them.
    Type: Grant
    Filed: August 27, 1998
    Date of Patent: April 27, 2004
    Assignee: Sage Pharmaceuticals, Inc.
    Inventor: Jivn-Ren Chen
  • Publication number: 20030203018
    Abstract: The present invention relates to new stable enteric coated pharmaceutical dosage forms for oral use containing Omeprazole or Lansoprazole, to a formulation and a method for the manufacture of such a dosage forms, and to a method of gastric acid pump inhibition and providing gastrointestinal cytoprotective benefit by using them.
    Type: Application
    Filed: April 24, 2003
    Publication date: October 30, 2003
    Applicant: Sage Pharmaceuticals, Inc.
    Inventor: Jivn-Ren Chen
  • Publication number: 20030170182
    Abstract: This invention relates to a topical spray preparation for burn treatment and microbial infections on human being or animals. This non-aerosol preparation contains an antimicrobial drug, i.e., silver sulfadiazine, as is dispersed or solubilized in a cream or lotion base matrix which can be sprayed directly from a common trigger spray device. The key component of the matrix can be characterized by it having a suitable molecular weight polymer of cross-linked acrylic acid, such as Carbomers or non-ionic surfactants such as polyoxyethylene alkyl ethers, or any combination of the above materials.
    Type: Application
    Filed: April 1, 2003
    Publication date: September 11, 2003
    Applicant: Sage Pharmaceuticals, Inc.
    Inventor: Jivn-Ren Chen
  • Patent number: 6551577
    Abstract: This invention relates to a topical spray preparation for burn treatment and microbial infections on human being or animals. This non-aerosol preparation contains an antimicrobial drug, i.e., silver sulfadiazine, as is dispersed or solubilized in a cream or lotion base matrix which can be sprayed directly from a common trigger spray device. The key component of the matrix can be characterized by it having a suitable molecular weight polymer of cross-linked acrylic acid, such as Carbomers or non-ionic surfactants such as polyoxyethylene alkyl ethers, or any combination of the above materials.
    Type: Grant
    Filed: June 23, 1999
    Date of Patent: April 22, 2003
    Assignee: Sage Pharmaceuticals, Inc.
    Inventor: Jivn-Ren Chen
  • Patent number: 5191114
    Abstract: Direct compressible ibuprofen particles are formed by treating commercially available, dry ibuprofen with a hydrophilic solvent in one embodiment, a mixture of a hydrophilic solvent and one or more hydrophobic organic solvents in a second embodiment and one or more hydrophobic organic solvents in a third embodiment, to change at least the external crystalline shape of the ibuprofen from a flow-retarding shape to a free-flowing, easily compressible configuration. A typical hydrophilic solvent is water and among the hydrophobic solvents which may be used are acetone, methyl alcohol, ethyl alcohol, isopropyl and N-propyl alcohol. Direct compressible ibuprofen particles having superior flow characteristics may also be prepared by mixing commercially available, dry ibuprofen with micron size, amorphous silica gel in various formulations.
    Type: Grant
    Filed: October 9, 1991
    Date of Patent: March 2, 1993
    Assignee: Sage Pharmaceuticals, Inc.
    Inventor: Jivn-Ren Chen