Abstract: The invention relates to a pharmaceutical composition for treating or diagnosing a disorder associated with production of peroxisome in a cell, comprising a polypeptide which has cysteine protease activity and directly processes peroxisomal enzymes targeted by PTS1 or PTS2 signals. Preferably, the polypeptide is encoded by Tysnd1.
Type:
Application
Filed:
December 10, 2007
Publication date:
July 3, 2008
Applicants:
Riken, Saitama Medical University
Inventors:
Igor Kurochkin, Christian Schoenbach, Yasushi Okazaki