Abstract: The present invention addresses the problem of providing a centrifugal smearing device and a sealed rotating container in which liquid components do not leak to an outside of the sealed rotating container. To solve this problem, in a centrifugal smearing device (30) including a sealed rotating container (34) that houses a chamber (10) with a slide glass removably attached for holding the liquid sample to smear cells in the liquid sample with a centrifugal force onto the slide glass, and a base (31) housing the sealed rotating container (34) and including rotational driving means (32) for rotating the sealed rotating container (34), the sealed rotating container (34) includes a main body (40) capable of housing the chamber (10) and a lid (42) for closing an upper surface opening portion of the main body (40), and has a storage section (46) for storing liquid scattered from the chamber (10) during being centrifuged, formed on an inside face of the main body (40).

Abstract: A thin-section sample fabrication apparatus includes a sample table that places a thin section cut out from an embedding block, a transporting mechanism that moves the thin section to the vicinity of the sample table, a liquid phase forming portion that forms a liquid phase having a predetermined amount of transfer liquid which continues from the transport surface onto the sample table, and a thin-section transfer portion that transfers the thin section onto the sample table so that a surface of the thin section opposing the transport surface opposes the sample table by surface tension of the liquid phase formed by the liquid phase forming portion.

Abstract: The present invention addresses the problem of providing a technology capable of automatically preparing a mixed liquid having a fixed ratio. To address the problem, the following processes are carried out in a tissue piece treating apparatus (10). (a) By use of a detection sensor (36), a dehydrating agent is transferred from a dehydrating agent tank (large-capacity tank (15)) to a treatment tank (11) until reaching a prescribed level. (b) By use of the detection sensor (36), an intermediate agent is transferred from an intermediate agent tank (large-capacity tank (17)) to the treatment tank (11) until reaching a prescribed level. (c) An admixture obtained by mixing the dehydrating agent by the process of (a) and the intermediate agent by the process of (b) is transferred from the treatment tank (11) to an admixture tank (14).

Abstract: A block storage device includes: a magazine which accommodates embedding blocks to be inserted into or removed from the magazine in a state where the embedding blocks held in a cassette to which ID data is attached are arranged vertically in one row; a magazine holding portion which detachably holds each of the magazines; and a reading portion which reads the ID data. The magazine holding portion includes a rotary body which is rotatable around a rotation axis O, a holding mechanism which is multiply provided on a circumferential wall portion in the rotary body and detachably holds the magazines individually, and a rotation drive portion which positions one of the magazines at a block extraction position facing the reading portion by rotating the rotary body, and the magazine positioned at the block extraction position and the reading portion are movable relative to each other along the vertical direction.

Abstract: The present invention addresses a problem of providing a tissue piece treating method and a tissue piece treating apparatus by which treatment of a tissue piece by each of liquid chemicals can be favorably performed and a running cost can be reduced.

Abstract: The invention provides a method for forming tissue pieces which allows stable and accurate winding around a core rod in rolling a sheet-like tissue piece, and a device therefor. In the tissue pieces used as each tissue piece in a tissue array obtained by arranging the tissue pieces on a substrate in an array form, the method for forming a roll-shaped tissue piece 6 obtained by rolling a sheet-like tissue piece 8 is characterized by the facts that the sheet-like tissue piece 8 is produced by slicing a tissue block 5 obtained by embedding the tissues with an embedding medium, the sheet-like tissue piece 8 is placed on a mounting block 12, peeling means 13 which easily enables peeling of the tissue piece 8 from the mounting block 12 is applied between the mounting block 12 and the tissue piece 8, and the tissue piece 8 is wound around a core rod 11 while heating the tissue piece 8 on the mounting block 12.

Abstract: An automatic thin section sample preparation device includes: a reading portion which reads the ID data; a first imaging portion which images a surface image of an embedding block; a sample preparation mechanism which prepares a thin section by thinly cutting the embedding block, fixes the thin section to a substrate, and prepares a thin section sample; a second imaging portion which images a thin section image of the thin section in the thin section sample; a recording portion which records individual data on the substrate in the thin section sample; and a control portion. The control portion includes a determination portion which determines whether or not the thin section is prepared from an original embedding block by collating the surface image and the thin section image, and a storage portion which stores the determination result from the determination portion in association with the ID data, as the individual data.

Abstract: A thin section fabrication apparatus includes an epi-imaging data acquisition unit that performs imaging by radiating epi-illumination and acquires imaging data, a diffusion imaging data acquisition unit that performs imaging by radiating diffusion illumination and acquires imaging data, an exposed shape extraction unit that extracts an exposed shape of an exposure portion of the biological sample which is exposed to a surface of the embedding block, based on the imaging data acquired by the epi-imaging data acquisition unit, an embedded shape extraction unit that extracts an embedded shape of an embedding portion of the biological sample which is embedded in the embedding block, based on the imaging data acquired by the diffusion imaging data acquisition unit, and a control unit that determines ending of the preliminary cutting by comparing the exposed shape extracted by the exposed shape extraction unit and the embedded shape extracted by the embedded shape extraction unit.

Abstract: A microtome comprising a head 32 which holds a sample, an alignment mechanism 50 which aligns the head 32, a body portion 42 which is provided on a back face side of the alignment mechanism 50, a cylindrical coupling portion 41 which couples the body portion 42 with the head 32, a temperature controller 34 in the head 32, and refrigerant piping 40 and electrical wiring 46 for the temperature controller 34, and the alignment mechanism 50 includes a spherical member 68 coupled with the back face side of the head and having a spherical outer periphery and includes retainer portions 70 and 71 retaining the outer periphery of the spherical member 68 slidably along a spherical surface, the spherical member 68 has a through hole 74 which communicates with the hollow portion 43 of the coupling portion 41, the refrigerant piping 40 and the electrical wiring 46 are connected with the temperature controller 34 in the head 32 through the through hole 74 of the spherical member 68 and the hollow portion 43 of the coupling

Abstract: A thin section fabrication apparatus includes an epi-imaging data acquisition unit that performs imaging by radiating epi-illumination and acquires imaging data, a diffusion imaging data acquisition unit that performs imaging by radiating diffusion illumination and acquires imaging data, an exposed shape extraction unit that extracts an exposed shape of an exposure portion of the biological sample which is exposed to a surface of the embedding block, based on the imaging data acquired by the epi-imaging data acquisition unit, an embedded shape extraction unit that extracts an embedded shape of an embedding portion of the biological sample which is embedded in the embedding block, based on the imaging data acquired by the diffusion imaging data acquisition unit, and a control unit that determines ending of the preliminary cutting by comparing the exposed shape extracted by the exposed shape extraction unit and the embedded shape extracted by the embedded shape extraction unit.

Abstract: Tissue array production method enables even roll-shaped tissue pieces having various diameters to be steadily fixed to a substrate block is provided. In a method in which roll-shaped tissue pieces formed by rolling sheet-like tissue pieces in the shape of a roll are arranged on a substrate in an array form, a tissue array is produced by placing a holding member which holds a plurality of roll-shaped tissue pieces so that their axis directions are vertically directed in a container into which a melted embedding medium is poured for its accumulation, to hold the respective roll-shaped tissue pieces in the holding member; pouring the embedding medium into the container, to form a substrate block constituted so that the plurality of roll-shaped tissue pieces is arranged in the array form; and slicing the substrate block so that the roll-shaped tissue pieces are ring-shaped.

Abstract: Problems of a conventional cover glass sticking device, in which a slide glass having one end side, where a describing portion is formed, is stored in a storage container and the one end side is always projected from level of a protection liquid therein, are solved by the device of the present invention.

Abstract: The present invention solves a problem of conventional tissue treating apparatuses: liquid chemicals which have been used given times and have become useless in a tissue specimen infiltration treatment and a cleaning liquid which has been used given times and has decreased in cleaning ability are required to be separately discarded/replaces.

Abstract: Provided is a microtome in which refrigerant piping and electrical wiring are not impeditive so that cleaning and other works can be surely conducted.

Abstract: The invention provides a method for forming tissue pieces which allows stable and accurate winding around a core rod in rolling a sheet-like tissue piece, and a device therefor. In the tissue pieces used as each tissue piece in a tissue array obtained by arranging the tissue pieces on a substrate in an array form, the method for forming a roll-shaped tissue piece 6 obtained by rolling a sheet-like tissue piece 8 is characterized by the facts that the sheet-like tissue piece 8 is produced by slicing a tissue block 5 obtained by embedding the tissues with an embedding medium, the sheet-like tissue piece 8 is placed on a mounting block 12, peeling means 13 which easily enables peeling of the tissue piece 8 from the mounting block 12 is applied between the mounting block 12 and the tissue piece 8, and the tissue piece 8 is wound around a core rod 11 while heating the tissue piece 8 on the mounting block 12.

Abstract: A tissue array production method which enables even roll-shaped tissue pieces having various diameters to be steadily fixed to a substrate block is provided. In the tissue array production method in which roll-shaped tissue pieces 6 formed by rolling sheet-like tissue pieces 8 in the shape of a roll are arranged on a substrate in an array form, the tissue array is produced by placing a holding member 16 which holds a plurality of roll-shaped tissue pieces 6 so that their axis directions are vertically directed in a container 10 into which a melted embedding medium is poured for its accumulation, to hold the respective roll-shaped tissue pieces 6 in the holding member 16; by pouring the embedding medium into the container 10, to form a substrate block 40 constituted so that the plurality of roll-shaped tissue pieces 6 is arranged in the array form; and by slicing the substrate block 40 so that the roll-shaped tissue pieces 6 are ring-shaped, to place the sliced pieces on the substrate.

Abstract: An analyte treatment apparatus comprising liquid chemical tanks storing liquid chemicals; and a treatment unit carrying out a treatment by supplying the liquid chemicals, so as to facilitate observation. The liquid chemical tanks are made of resin and housed inside a housing unit. Openings are formed in the housing unit. Light projecting means is provided outside of the treatment unit and projects light into each liquid chemical tank through the opening of the housing unit. A colored transparent door is provided to the housing unit and located at the other side with respect to a specific side of the liquid chemical tanks from which light diffusely reflected at the one side and the opposite side of the liquid chemical tank or in the liquid chemical tank can be visually checked, so as to visually check the reflected light. A control unit controls ON-OFF switching of the light projecting means.

Abstract: To provide a thin-section manufacturing apparatus capable of firmly receiving and transferring a thin-section made by sectioning an embedded block by bringing a transfer belt into a wet state, a thin-section manufacturing apparatus 1 includes a cutter 3 of sectioning an embedded block B, a cutter fixing portion 15 having a fixing base 16 of supporting the cutter 3 and an cutter holder 17 of squeezing the cutter 3 from an upper side, a sample base of fixing the embedded block B, feeding means 4 for moving the sample base 2 relative to the cutter 3 in a predetermined feeding direction X, a liquid bath 6 arranged on a rear side of a cut edge 3a of the cutter 3 for storing a liquid W, and a transfer belt 20 in an endless shape having a first turn back portion 20a provided on an upper side of the cutter 3 and a second turn back portion 20b provided at an inner portion of the liquid bath 6 for transferring a thin-section B1 to the liquid bath 6, an upper face of the cutter holder 17 is formed with a liquid storing

Abstract: The present invention can solve such a problem that a conventional tissue piece treating apparatus has difficulty of reduction in size and restriction on installation and stopping subsequent treatment operations when the amount of chemical supplied to a processing chamber is insufficient.

Abstract: The staining and sticking system includes a staining device and a sticking device provided separately from the staining device. The staining device stains a specimen in a predetermined color by dipping a basket containing a glass slide with the specimen in a plurality of tubs sequentially. The sticking device sticks a cover film piece onto the stained specimen on the glass slide, which has been taken out of the basket transferred from the staining device by transfer means. A staining control unit and a sticking control unit are interconnected so as to communicate with each other. Sticking condition data, related to the basket fed from the staining device, out of staining condition data and sticking condition data inputted to the staining control unit correspondingly to baskets, are sent from the staining control unit to the sticking control unit, and then the sticking device sticks the cover film piece.