Patents Assigned to Sakura Finetek U.S.A., Inc.
  • Patent number: 11898945
    Abstract: A microtome blade guard including a first arm operable to be coupled to a first side of a cutting mechanism of a microtome; a second arm operable to be coupled to a second side of a cutting mechanism; a lateral support member disposed between the first arm and the second arm; and a staff coupled to the lateral support member and operable to extend therefrom to engage a blade positioned in the blade slot. A microtome including a blade guard and a method including placing a blade in a blade slot of a blade block of a microtome; engaging the blade with a staff coupled to a blade guard that is coupled to the blade block; and moving the blade with the staff.
    Type: Grant
    Filed: September 18, 2020
    Date of Patent: February 13, 2024
    Assignee: SAKURA FINETEK U.S.A., INC.
    Inventor: Lawrence H. Dirks
  • Patent number: 11796429
    Abstract: A sectionable tissue sample support structure including a gel compound formed into a self supporting geometric shape for retention and orientation of at least one tissue sample during a histopathology process including processing, embedding and microtome slicing of the tissue sample. A method of orienting, processing, embedding and microtome slicing a tissue sample using a gel compound preformed into a self supporting geometric shape. A combination including the sectionable tissue sample support structure and a package containing the sectionable tissue sample support structure.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: October 24, 2023
    Assignees: BIOPATH AUTOMATION, LLC, SAKURA FINETEK U.S.A., INC.
    Inventors: Warren P. Williamson, IV, Richard W. Dapson, Amit D. Shah
  • Patent number: 11719604
    Abstract: Handheld forceps comprising: a body comprising trunk and a first arm and a second arm extending from a base of the trunk coupled at one end and separated from one another at a second end; a rod disposed in the body, the rod comprising a first end positioned in the first arm and a second end positioned in the second arm and forming an apex in the trunk; a compression spring disposed around the apex of the rod in the trunk; and a button coupled to the apex of the rod and protruding through an opening in the trunk. Also a method of using the handheld forceps.
    Type: Grant
    Filed: July 6, 2021
    Date of Patent: August 8, 2023
    Assignee: SAKURA FINETEK U.S.A., INC.
    Inventors: Joshua Greenlee, Erico von Bueren, Robert Jeffrey Sheppard
  • Publication number: 20230055997
    Abstract: A processor assembly including: an exposure station operable to expose a sample on a slide; a print station operable to apply a reagent to the exposed sample through a thermal inkjet process; and a robotic transfer mechanism to transfer the slide from the exposure station to the print station. Also, a reagent cartridge including: a body defining a container having a volume therein; a nonmetallic bag in the container operable to contain a reagent; and a printhead at a base of the body, the printhead coupled to an outlet of the bag. Further, a method including exposing a sample on a slide in a processor assembly; robotically transferring the slide to a printing station of the processor assembly; and applying a reagent to the exposed sample at the printing station by a thermal inkjet printing process.
    Type: Application
    Filed: December 31, 2020
    Publication date: February 23, 2023
    Applicant: Sakura Finetek U.S.A., Inc.
    Inventors: Amit D. SHAH, Scott WEBSTER, Cristina R. FLORES, Chen Yu CHENG, Chia Hsien LIN, Chih Shun CHUANG, Nicholas John BOOKER, Andrew Douglas WATKINS, Rebecca Jean BARTEL, Chester John HENDERSON, Erico VON BUEREN, Michael YANG
  • Publication number: 20230031492
    Abstract: A processor assembly including a core module operable to expose a sample on a slide; a staining module operable to apply a stain to the exposed sample; and a robotic transfer mechanism to transfer the slide from the core module to the staining module. Also, an apparatus including a rectangular body having an open rear end and an opposite front end; a flange having a first side and a second side, wherein the first side of the flange is coupled to the front end of the body; and a pair of legs extending from second side of the flange, wherein the pair of legs are operable to engage opposite side edges of a slide.
    Type: Application
    Filed: December 31, 2020
    Publication date: February 2, 2023
    Applicant: Sakura Finetek U.S.A., Inc.
    Inventors: Amit D. Shah, Scott WEBSTER, Nicholas John BOOKER, Andrew WATKINS, Chester HENDERSON, Rebecca J. BARTEL, Erico VON BUEREN, Michael YANG
  • Patent number: 11460400
    Abstract: Apparatuses for measuring sample materials (such as tissue samples) and associated methodologies and instrumentation involve a spectroscopy system or device configured with a sample measuring device (e.g., an attenuated total reflection infrared (ATR-IR) sample measuring device) including a crystal defining a sample receiving surface/interface operatively connected to an IR source and an IR detector. The sample receiving surface/interface facilitates assessing presence (and optionally, amount) of a fixative (e.g., formaldehyde) in sample materials, tissue samples for example. Measurements are taken at one or multiple locations within a sample placement structure/area, which can be provided in the form of a probe or a raised piercing structure containing one or more ATR-IR (or other) sample measuring devices.
    Type: Grant
    Filed: July 7, 2020
    Date of Patent: October 4, 2022
    Assignee: SAKURA FINETEK U.S.A., INC.
    Inventors: Amit D. Shah, Cristina R. Flores
  • Publication number: 20220090990
    Abstract: A microtome blade guard including a first arm operable to be coupled to a first side of a cutting mechanism of a microtome; a second arm operable to be coupled to a second side of a cutting mechanism; a lateral support member disposed between the first arm and the second arm; and a staff coupled to the lateral support member and operable to extend therefrom to engage a blade positioned in the blade slot. A microtome including a blade guard and a method including placing a blade in a blade slot of a blade block of a microtome; engaging the blade with a staff coupled to a blade guard that is coupled to the blade block; and moving the blade with the staff.
    Type: Application
    Filed: September 18, 2020
    Publication date: March 24, 2022
    Applicant: Sakura Finetek U.S.A., Inc.
    Inventor: Lawrence H. Dirks
  • Publication number: 20220090994
    Abstract: An apparatus including a reagent cartridge and a reaction chamber, the reagent cartridge having a reagent capsule removably positioned therein for dispensing of a reagent onto the reaction chamber. A system including a linearly translatable mounting assembly having a plurality of mounting stations dimensioned to receive at least one fluid dispensing cartridge, a linearly translatable bulk reagent dispensing assembly having a plurality of bulk reagent dispensing nozzles coupled thereto and a receiving assembly positioned beneath the mounting assembly and the bulk reagent dispensing assembly, the receiving assembly including a plurality of reaction stations.
    Type: Application
    Filed: December 6, 2021
    Publication date: March 24, 2022
    Applicant: Sakura Finetek U.S.A., Inc.
    Inventors: Xuan S. Bui, Anthony L. Hartman, Toshiyuki Fujimaki, Shinji Tokudaiji, Yoshitake Okabe, Yoshitada Mizusawa
  • Patent number: 11280711
    Abstract: A method including placing a biological sample taken from a body into a chamber; adding a composition including an acetal solvent to the chamber; and fixating the biological sample. A method including placing a tissue from a body into a chamber; and contacting the tissue with a composition including an acetal solvent as a fixating process.
    Type: Grant
    Filed: October 8, 2018
    Date of Patent: March 22, 2022
    Assignee: Sakura Finetek U.S.A., Inc.
    Inventor: Amit D. Shah
  • Patent number: 11280803
    Abstract: An apparatus including a first and a second imaging module; a storage module; an automated transport module operable to transport at least one slide; and a controller operable to direct transport of the at least one slide by the transport module into the first imaging module and into the second imaging module. A method and a machine-readable medium including program instructions to cause a controller to perform a method including transporting at least one slide to a first imaging module using an automated transport module; capturing by the first imaging module of an image of a specimen on the at least one slide; transporting the at least one slide to a storage module using the automated transport module; and transporting the at least one slide to a second imaging module in response to a request for capturing an image in addition to the image captured by the first imaging module.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: March 22, 2022
    Assignee: SAKURA FINETEK U.S.A., INC.
    Inventors: Erico Von Bueren, Ralf Van Den Berg
  • Publication number: 20220018735
    Abstract: Handheld forceps comprising: a body comprising trunk and a first arm and a second arm extending from a base of the trunk coupled at one end and separated from one another at a second end; a rod disposed in the body, the rod comprising a first end positioned in the first arm and a second end positioned in the second arm and forming an apex in the trunk; a compression spring disposed around the apex of the rod in the trunk; and a button coupled to the apex of the rod and protruding through an opening in the trunk. Also a method of using the handheld forceps.
    Type: Application
    Filed: July 6, 2021
    Publication date: January 20, 2022
    Applicant: SAKURA FINETEK U.S.A., INC.
    Inventors: Joshua Greenlee, Erico von Bueren, Robert Jeffrey Sheppard
  • Patent number: 11193859
    Abstract: An apparatus including a reagent cartridge and a reaction chamber, the reagent cartridge having a reagent capsule removably positioned therein for dispensing of a reagent onto the reaction chamber. A system including a linearly translatable mounting assembly having a plurality of mounting stations dimensioned to receive at least one fluid dispensing cartridge, a linearly translatable bulk reagent dispensing assembly having a plurality of bulk reagent dispensing nozzles coupled thereto and a receiving assembly positioned beneath the mounting assembly and the bulk reagent dispensing assembly, the receiving assembly including a plurality of reaction stations.
    Type: Grant
    Filed: May 20, 2019
    Date of Patent: December 7, 2021
    Assignee: Sakura Finetek U.S.A., Inc.
    Inventors: Xuan S. Bui, Anthony L. Hartman, Toshiyuki Fujimaki, Shinji Tokudaiji, Yoshitake Okabe, Yoshitada Mizusawa
  • Patent number: 11193950
    Abstract: An apparatus including a receptacle including a slot for receiving a basket; a push bar disposed in the receptacle, the push bar having an end to contact an edge of a single slide of a plurality of slides in a basket, the push bar including a first position below a bottom surface of a base of a basket that is received in the slot and a second position in the slot; and a sensor focused in a direction of the slot operable to acquire information from a slide in a received basket. A method including placing a slide basket into a slot of a receptacle; individually raising one or more slides from a respective position in the basket; using a sensor, acquiring information from the raised slide in the basket; and after acquiring information, lowering the raised slide.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: December 7, 2021
    Assignee: SAKURA FINETEK U.S.A., INC.
    Inventors: Erico von Bueren, Niccolo von Bueren, Xuan S. Bui
  • Patent number: 11112337
    Abstract: A sample sectioning device including a cutting mechanism that is operable to cut sections from a sample, a sample holder operable to move relative to the cutting mechanism, the sample holder having a first side and a second side, the first side faces the cutting mechanism and is dimensioned to receive a sample, a light source coupled to the sample holder, wherein the light source is operable to emit a light from the first side of the sample holder and through a sample positioned on the first side, and a generator operable to generate an electrical energy for providing power to the light source.
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: September 7, 2021
    Assignee: SAKURA FINETEK U.S.A., INC.
    Inventors: Xuan S. Bui, Alyicia Marie Rios, Erico Von Bueren
  • Patent number: 10877054
    Abstract: A specimen slide for holding tissue specimens, and a method of loading tissue specimens on the specimen slide are described. The specimen slide can be printed with control and patient information corresponding to respective control and patient tissue specimens mounted on the specimen slide. The control and patient information can be printed at different times. The control information may be printed before loading the control tissue specimen on the specimen slide, and the patient information can be printed after loading the control tissue specimen on the specimen slide. The control and patient information may be encoded in a first barcode and a second barcode, respectively. The barcodes can have different configurations, such as different barcode types or different orientations. Other embodiments are also described and claimed.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: December 29, 2020
    Assignee: Sakura Finetek U.S.A., Inc.
    Inventor: Erico Von Bueren
  • Patent number: 10794804
    Abstract: A sectionable tissue sample support structure including a gel compound formed into a self supporting geometric shape for retention and orientation of at least one tissue sample during a histopathology process including processing, embedding and microtome slicing of the tissue sample. A method of orienting, processing, embedding and microtome slicing a tissue sample using a gel compound preformed into a self supporting geometric shape. A combination including the sectionable tissue sample support structure and a package containing the sectionable tissue sample support structure.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: October 6, 2020
    Assignees: BioPath Automation, LLC, Sakura Finetek U.S.A., Inc.
    Inventors: Warren P. Williamson, IV, Richard W. Dapson, Amit D. Shah
  • Publication number: 20200309800
    Abstract: An apparatus including a receptacle including a slot for receiving a basket; a push bar disposed in the receptacle, the push bar having an end to contact an edge of a single slide of a plurality of slides in a basket, the push bar including a first position below a bottom surface of a base of a basket that is received in the slot and a second position in the slot; and a sensor focused in a direction of the slot operable to acquire information from a slide in a received basket. A method including placing a slide basket into a slot of a receptacle; individually raising one or more slides from a respective position in the basket; using a sensor, acquiring information from the raised slide in the basket; and after acquiring information, lowering the raised slide.
    Type: Application
    Filed: March 29, 2019
    Publication date: October 1, 2020
    Applicant: SAKURA FINETEK U.S.A., INC.
    Inventors: Erico von Bueren, Niccolo von Bueren, Xuan S. Bui
  • Patent number: D909876
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: February 9, 2021
    Assignee: SAKURA FINETEK U.S.A., INC.
    Inventor: Joseph Sestak
  • Patent number: D920121
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: May 25, 2021
    Assignee: SAKURA FINETEK U.S.A., INC.
    Inventor: Joseph T. Sestak
  • Patent number: D923478
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: June 29, 2021
    Assignee: SAKURA FINETEK U.S.A., INC.
    Inventor: Joseph T. Sestak