Abstract: Gene therapy compositions and methods are provided that make use of novel transposases and/or chimeric transposases for targeted transposition.
Type:
Grant
Filed:
March 29, 2023
Date of Patent:
May 28, 2024
Assignee:
Saliogen Therapeutics, Inc.
Inventors:
Joseph J. Higgins, Scott McMillan, Ray Tabibiazar
Abstract: Gene therapy compositions and methods are provided that make use of transposases and/or chimeric transposases for targeted transposition, including engineered enzymes and nucleic acids encoding the same. The provided compositions and methods are suitable of treating, for example, an inherited or acquired disease in a patient, as well as treating and/or mitigating a variety of diseases.
Type:
Grant
Filed:
February 11, 2022
Date of Patent:
January 3, 2023
Assignee:
Saliogen Therapeutics, Inc.
Inventors:
Joseph J. Higgins, Scott McMillan, Ray Tabibiazar