Abstract: The present invention relates to a recombinant fusion protein comprising a fragment of the cardioprotective protein neuregulin-1 (NRG-1) fused to a monoclonal antibody (mAb) backbone and to a method of treating a disease or condition in a subject in need thereof comprising administering a therapeutically effective amount of the recombinant fusion protein or the pharmaceutical composition comprising the recombinant fusion protein disclosed herein.
Type:
Grant
Filed:
May 21, 2021
Date of Patent:
August 8, 2023
Assignees:
Salubris Biotherapeutics, Inc.
Inventors:
John Li, Shengwei Li, Dixiang Luo, Yiran Wu, Ming Zhou, Yang Wang, Xiaolei Zhuang, Liang Hua, Pengyi Luo
Abstract: The present invention relates to a recombinant fusion protein comprising a fragment of the cardioprotective protein neuregulin-1 (NRG-1) fused to a monoclonal antibody (mAb) backbone and to a method of treating a disease or condition in a subject in need thereof comprising administering a therapeutically effective amount of the recombinant fusion protein or the pharmaceutical composition comprising the recombinant fusion protein disclosed herein.