Abstract: A vascular device for use during an interventional procedure, the device having a stent structure having a collapsed configuration, an expanded configuration, a proximal end, and a distal end; and a delivery member for delivering the stent to a treatment site within a vasculature, wherein the proximal end of the stent structure is fixed to the delivery member when the stent structure is in the expanded configuration at the treatment site.

Abstract: A embolic protection system 1 comprises a guidewire 99 for advancing through a vasculature, the guidewire 99 having a distal end and a proximal end; an embolic protection filter 1 having a filter body 41 with a distal end and a proximal end, the filter body 41 providing for a collapsed configuration and an expanded deployed configuration. The embolic protection filter body 41 has a guidewire path for slidably receiving the guidewire 99 to permit movement of the filter 1 relative to the guidewire 99 when the filter 1 is in the collapsed configuration and the expanded deployed configuration. A delivery catheter 2 is advanceable over the guidewire 99 for delivery of the embolic protection filter 1; the delivery catheter 2 having a proximal end and a distal end. The filter 1 is deployed from the distal end of the delivery catheter 2 into the expanded deployed configuration.

Abstract: A collapsible filter element for a transcatheter embolic protection device, the filter element comprises a collapsible filter body of polymeric material which is movable between a collapsed stored position for movement through a vascular system and an expanded position for extension across a blood vessel such that blood passing through the blood vessel is delivered through the filer element. A proximal inlet portion of the filter body has one or more inlet openings sized to allow blood and embolic material enter the filter body. A distal outlet portion of the filter body has a plurality of generally circular outlet openings sized to allow through-passage of blood, but to retain embolic material within the filter body. The distal outlet portion of the filter body in the region of the outlet openings has means for reducing shear stress on blood passing through the outlet openings. The shear stress reducing means includes lead-in and lead-out radiussed portions of the filter body leading to the outlet holes.

Abstract: An embolic protection device comprises a collapsible filter body and a filter support for the filter body. The filter support comprises a support frame defined by at least two wire segments having terminations. The terminations of adjacent segments are fixed relative to one another and extend generally parallel in a bifilar manner for enhanced trackability and flexibility.

Abstract: A delivery catheter 1 has a distal pod 2 for reception of an embolic protection filter 3. The filter 2 is moved from a retracted delivery configuration to an extended deployed configuration by a push wire 6, which may comprise a push element 7 at its distal end for engagement with the filter 2. For example, retraction of a handle 9 has the effect of retracting the pod 3 relative to the push wire 6 and the filter 2 is effectively deployed by pushing it out of the pod 3. The filter 2 and catheter 1 are advanced to a treatment site over a guidewire, wherein the push wire 6 and push element 7 are completely separate from the guidewire.

Abstract: An embolic protection system having a guidewire for advancing through a vasculature; an embolic protection filter having a filter body with a distal end and a proximal end, the filter body providing for a collapsed configuration and an expanded deployed configuration. The embolic protection filter body has a guidewire path for slidably receiving the guidewire to permit movement of the filter relative to the guidewire when the filter 1 is in the collapsed configuration and the expanded deployed configuration. A delivery catheter is advanceable over the guidewire for delivery of the embolic protection filter. A retrieval catheter is also advanceable over the guidewire for retrieval of the filter , and engagement elements are used for engaging the embolic protection filter with the guidewire for retrieval of the filter into the retrieval catheter in the collapsed configuration.

Abstract: A delivery catheter 1 has a distal pod 2 for reception of an embolic protection filter 3. The filter 2 is moved from a retracted delivery configuration to an extended deployed configuration by a push wire 6 which has an engagement hoop 7 at the distal end. Retraction of a handle 9 has the effect of retracting the pod 3 relative to the push wire 6 and the engagement hoop 7 and the filter 2 is effectively deployed by pushing it out of the pod 3.

Abstract: A medical guidewire assembly comprises a guidewire having a flexible tip. A medical device such as a collapsible filter for use as an embolic protection device is mounted on the guidewire. The filter is advanced through a body lumen with the guidewire tip extending distally. A variable thickness guidewire (having a recess or thinner segment between thicker segments) can be employed. At a first location the filter is advanced relative to the tip to a location which is distally advanced from the first location. Placement of the filter in an optimal distal location is thereby achieved.

Abstract: A support 103 for an embolic protection device comprises round wires 116 which may form one or more support hoops for a filter body. The circumferential hoop formed by the wires 116 ensures that in the expanded position, the filter body 102 will be supported by the support frame 103 in circumferential apposition with the interior wall of the vasculature. The wires 116 may have a strain distributing linkage element in the form of a loop 120. The loop 120 acts as a diameter or circumference adjuster allowing an embolic protection device to adapt to different Bessel contours and sizes whilst maintaining apposition with the vessel wall. The strain relieving geometry of the loops enhances the compliance of the bend points without creating a weakened hinge point, thus ensuring that there is no discontinuity in the circumferential seal against the vessel wall.

Abstract: A device and method for liberating plaque from a lumen after a medical procedure has been formed. The device includes a catheter having a first expandable member and a second expandable member.

Abstract: An embolic protection device comprises a collapsible filter element for delivery through a vascular system of a patient. The filter element comprising a collapsible filter body and a filter support frame contacting the filter body. The collapsible filter body has an inlet end and an outlet end, the inlet end of the filter body having one or more inlet openings sized to allow blood and embolic material to enter the filter body, the outlet end of the filter body having a plurality of outlet openings sized to allow through passage of blood but to retain undesired embolic material within the filter body. The filter support frame is movable between a collapsed position for movement through the vascular system and an extended outwardly projecting position to support the filter body in the expanded position.

Abstract: A medical guidewire assembly comprises a guidewire having a flexible tip. A medical device such as a collaptible filter for use as an embolic protection device is mounted on the guidewire. The filter is advanced through a body lumen with the guidewire tip extending distally. At a first location the filter is advanced relative to the tip to a location which is distally advanced from the first location. Placement of the filter in an optimal distal location is thereby achieved.

Abstract: An embolic protection device has a collapsible filter element (105) mounted on a carrier such as a guidewire (101). The filter element (105) collapses into the outer end of a catheter (118) for deployment and retrieval through a vascular system of a patient. The filter element (105) has a collapsible filter body with a proximal inlet end and a distal outlet end The proximal inlet end has inlet openings sized to allow blood and embolic material enter the filter body. The outlet end has outlet openings which allow through passage of blood but retain embolic material within the filter body. After use, the catheter (118) is movable along the guidewire (101) to engage the proximal end of the filter element and close the inlet openings before sliding over the fitter element from the proximal end to the distal end to progressively collapse the filter body on the guidewire (101) for retrieval.

Abstract: An embolic protection filter for deployment in a vasculature, the filter having an inlet end and an outlet end, the inlet end having one or more inlet openings sized to allow blood and embolic material enter the filter, and the outlet end of the filter having a plurality of outlet openings sized to allow through passage of blood but to retain undesired embolic material within the filter. The filter is movable between a collapsed configuration for movement through a vasculature, and an outwardly extended configuration for deployment in a vasculature. The filter at least in the collapsed configuration was a guidewire lumen defined at least partially therethrough for passing the filter over a guidewire. The guidewire lumen is defined by a lumen-defining member which is spaced proximally of the distal end of the filter.

Abstract: A device for loading an embolic protection filter into a catheter including a loading member for collapsing an embolic protection filter, wherein an outlet of the loading member is configured to be aligned with an inlet of a catheter extending along at least part of an exterior surface of the catheter for loading of the collapsed embolic protection filter into the catheter. The loading member may have a passageway extending therethrough, through which an embolic protection filter may be passed to collapse the embolic protection filter. The outlet of the loading member may include an outlet of the passageway that is at least partially funnel-shaped. The loading member may include a tubular part extendable along part of an exterior surface of a catheter, the outlet of the loading member being provided at an end of the tubular part.

Abstract: An embolic protection device comprises a collapsible filter element for delivery through a vascular system of a patient. The filter element comprising a collapsible filter body and a filter support frame contacting the filter body. The collapsible filter body has an inlet end and an outlet end, the inlet end of the filter body having one or more inlet openings sized to allow blood and embolic material to enter the filter body, the outlet end of the filter body having a plurality of outlet openings sized to allow through passage of blood but to retain undesired embolic material within the filter body. The filter support frame is movable between a collapsed position for movement through the vascular system and an extended outwardly projecting position to support the filter body in the expanded position.

Abstract: The method comprises the steps of advancing a guidewire from a first intermediate location to a further intermediate location which is proximal of the treatment location and, subsequently, advancing a medical device over the guidewire toward the further intermediate location. The method may comprise repeating these steps for additional intermediate locations. In one case the treatment location is in the carotid artery. The treatment location may be at or adjacent to the carotid bifurcation. An intermediate location may be at or adjacent to the aortic arch. An intermediate location may be at or adjacent to the carotid take-off. The medical device may be delivered over the guidewire using a delivery catheter. The delivery catheter and the medical device may be advanced through the vasculature without the use of a guide catheter.

Abstract: An assembly for loading a collapsible embolic protection filter 1 into a catheter 2, comprises a catheter 2 defining a reception space at a distal end of the catheter 2 for receiving a collapsed embolic protection filter 1; and a separate removable pushing device 8 for delivering the embolic protection filter 1 into the reception space. The pushing device 8 comprises an elongate stem 71 with a proximal stop 72 for engagement with the filter 1. A separate loading device 7 to collapse the embolic protection filter 1 is also provided. The loading device 7 defines an inlet end and an outlet end, the outlet end being configured for co-operative alignment with the reception space.

Abstract: An assembly for loading a collapsible embolic protection filter 1 into a catheter 2, comprises a catheter 2 defining a reception space at a distal end of the catheter 2 for receiving a collapsed embolic protection filter 1; and a separate removable pushing device 8 for delivering the embolic protection filter 1 into the reception space. The pushing device 8 comprises an elongate stem 71 with a proximal stop 72 for engagement with the filter 1. A separate loading device 7 to collapse the embolic protection filter 1 is also provided. The loading device 7 defines an inlet end and an outlet end, the outlet end being configured for co-operative alignment with the reception space.

Abstract: An embolic protection device has a collapsible filter element (105) mounted on a carrier such as a guidewire (101). The filter element (105) collapses into the outer end of a catheter (118) for deployment and retrieval through a vascular system of a patient. The filter element (105) has a collapsible filter body with a proximal inlet end and a distal outlet end. The proximal inlet end has inlet openings sized to allow blood and embolic material enter the filter body. The outlet end has outlet openings which allow through passage of blood but retain embolic material within the filter body. After use, the catheter (118) is movable along the guidewire (101) to engage the proximal end of the filter element and close the inlet openings before sliding over the filter element from the proximal end to the distal end to progressively collapse the filter body on the guidewire (101) for retrieval.