Abstract: A method of combination therapy for prevention and/or treatment of c-Met- and/or EGFR-induced diseases including co-administering a pharmaceutically effective amount of an EGFR antagonist and a pharmaceutically effective amount of an anti-c-Met antibody to a subject in need thereof is provided.

Abstract: An apparatus and a method for combining three-dimensional ultrasound images are provide. The method involves obtaining a plurality of three-dimensional ultrasound image data that corresponds to a Region of Interest (ROI); detecting one or more landmarks, using a parameter for detection; outputting the detection result and receiving a response from a user; registering each of one or more selected landmarks as link information according to a received response from the user; and generating a combined three-dimensional ultrasound image by combining at least two pieces of three-dimensional ultrasound image data using at least one of the one or more selected landmarks registered as the link information, wherein the at least two pieces of three-dimensional ultrasound image data commonly comprise the at least one of the one or more selected landmarks.

Abstract: An apparatus and a method predict a patient's potential change of Coronary Artery Calcification (CAC) level using various risk factors including a Coronary Artery Calcification Score (CACS). The apparatus includes a receiving unit, a cluster determining unit, a risk factor score extracting unit, a prediction model storage unit, a prediction model learning unit, and a predicting unit, and the method includes a receiving process, a risk factor score extracting process, and an operation performing process.

Abstract: The present invention relates to a peptide promoting angiogenesis and novel use thereof. More particularly, the invention relates to peptides promoting angiogenesis, and the use of the peptide for promoting angiogenesis and preventing or treating angiogenesis-related disease. The peptide of the present invention have an excellent effect on promoting angiogenesis. Accordingly, it is useful for preventing or treating angiogenesis-related disease and for preparing regeneration of skin flap, wound and burn healing, implantation of artificial-skin and preparation of blood vessels for transplantation.

Abstract: According to one embodiment of the present invention, an apparatus for measuring and treating dysphagia may comprise: one or more dysphagia measuring sensor units attached to the neck of a patient; one or more electrical stimulation electrode units attached to the neck of the patient to provide electrical stimulation to the neck of the patient in accordance with the dysphagia signal sensed by the dysphagia measuring sensor units so as to resolve the dysphagia; and a control unit which controls the dysphagia measuring sensor units and the electrical stimulation electrode units.

Abstract: An apparatus and a method for combining three-dimensional ultrasound images are provide. The method involves obtaining a plurality of three-dimensional ultrasound image data that corresponds to a Region of Interest (ROI); detecting one or more landmarks, using a parameter for detection; outputting the detection result and receiving a response from a user; registering each of one or more selected landmarks as link information according to a received response from the user; and generating a combined three-dimensional ultrasound image by combining at least two pieces of three-dimensional ultrasound image data using at least one of the one or more selected landmarks registered as the link information, wherein the at least two pieces of three-dimensional ultrasound image data commonly comprise the at least one of the one or more selected landmarks.

Abstract: A method of combination therapy for prevention and/or treatment of c-Met- and/or EGFR-induced diseases including co-administering a pharmaceutically effective amount of an EGFR antagonist and a pharmaceutically effective amount of an anti-c-Met antibody to a subject in need thereof is provided.

Abstract: According to one embodiment of the present invention, an apparatus for measuring and treating dysphagia may comprise: one or more dysphagia measuring sensor units attached to the neck of a patient; one or more electrical stimulation electrode units attached to the neck of the patient to provide electrical stimulation to the neck of the patient in accordance with the dysphagia signal sensed by the dysphagia measuring sensor units so as to resolve the dysphagia; and a control unit which controls the dysphagia measuring sensor units and the electrical stimulation electrode units.

Abstract: Disclosed is a method for providing information on the therapeutic effect of an SSRI antidepressant by identifying TPH2 gene polymorphism rs4760815, SLC6A4 gene polymorphism 5-HTTLPR, SLC6A4 gene polymorphism rs2066713, GAD1 gene polymorphism rs3828275, and GRIK2 gene polymorphism rs543196. Through the disclosed method, it is possible to select an antidepressant based on genetic information, to prevent the worsening or relapse of depression, and to establish customized depression treatment models which are effective in the development of customized new drugs, and appropriate for Korean people. Therefore, the base of domestic clinical trials can be expanded, which will enhance competitive power in the pharmaceutical market and preoccupy technology of drug prediction.

Abstract: A mouse model in which human fetal thymus and human fetal bone fragments are transplanted into NSG mice, a method of producing the same, and a use thereof.

Abstract: A musical brain fitness system according to an exemplary embodiment of the present invention includes: a display device configured to display a visual signal according to selected music; a control box configured to control the display device by receiving input of a user; and a controller including an acceleration sensor, and configured to drive the acceleration sensor according to a movement of the user to transmit a signal to the control box, in which the control box compares the signal received from the controller with a signal controlling the display device, processes the comparison, and outputs a result of the comparison.

Abstract: The embodiment of the present invention provides an ultrasound diagnostic system, including: an ultrasound diagnosis unit for transmitting ultrasound signals to a target object and receiving ultrasound echo signals to acquire B-mode image signals and Doppler spectrum image signals; a processor for forming at least one B-mode image based on the B-mode image signals and forming a plurality of Doppler spectrum images for a plurality of sample volumes designated on the B-mode image based on the Doppler spectrum image signals; a user input unit for allowing a user to input selection information indicating locations and sizes of the plurality of sample volumes; and an image display unit for displaying at least one B-mode image and the plurality of Doppler spectrum images.

Abstract: A system for controlling a therapy machine is a method for controlling a therapy machine for irradiating radiation onto a patient whose body has been stabilized. The method acquires a video signal constituted by a plurality of pixels including information on the posture of the patient; converts the video signal to digital format, and generates video data including information on characteristic values of each of the plurality of pixels; and calculates, on the basis of the information, the number of pixels from among the plurality of pixels of which the characteristic values lie outside a predetermined range. Then, the therapy machine is controlled based on the calculated number. Thus, medical accidents due to inattention during observation by therapists may be prevented, and the accuracy of therapy through the therapy machine may be improved.

Abstract: Disclosed is a method for providing information on the therapeutic effect of an SSRI antidepressant by identifying TPH2 gene polymorphism rs4760815, SLC6A4 gene polymorphism 5-HTTLPR, SLC6A4 gene polymorphism rs2066713, GAD1 gene polymorphism rs3828275, and GRIK2 gene polymorphism rs543196. Through the disclosed method, it is possible to select an antidepressant based on genetic information, to prevent the worsening or relapse of depression, and to establish customized depression treatment models which are effective in the development of customized new drugs, and appropriate for Korean people. Therefore, the base of domestic clinical trials can be expanded, which will enhance competitive power in the pharmaceutical market and preoccupy technology of drug prediction.

Abstract: A stent that maintains flexibility in a length direction and prevents fatigue failure by securing predetermined durability is disclosed. The stent may includes a plurality of cylindrical members having a hollow cylindrical shape with both ends open, and adapted to decrease a diameter thereof by an external force so as to be mounted in a tubule, and a connecting member connecting cylindrical members confronting each other.

Abstract: A method for coating bioactive material and a structured coated with a bioactive material are disclosed. The bioactive material coating method includes: flowing a coating solution, produced as a bioactive material is dissolved in a mixed solvent, inside a structure having a lumen; and coating the bioactive material on at least one of inner and outer surfaces of the structure, with different concentrations. The mixed solvent is mixed with two or more solvents having different features. The occurrence of the strangulation of blood vessels and inflammation can be reduced. An increase in the size of the myofibroblast is not suppressed. The coating solution is produced as a medication is dissolved in a mixed solvent, where the mixed solvent is produced as a polar solvent and a nonpolar solvent are mixed with each other at a certain ratio.

Abstract: Disclosed herein is a therapeutic composition for erectile dysfunction comprising as an active ingredient a gene functioning to inhibit expression of an ion channel involved in influx of ions into a tissue. When expressed, the gene inhibits the activity of the ion channel to effectively block calcium influx. Accordingly, the composition can be effective for treating erectile dysfunction without side effects.

Abstract: A method for coating bioactive material and a structured coated with a bioactive material are disclosed. The bioactive material coating method includes: flowing a coating solution, produced as a bioactive material is dissolved in a mixed solvent, inside a structure having a lumen; and coating the bioactive material on at least one of inner and outer surfaces of the structure, with different concentrations. The mixed solvent is mixed with two or more solvents having different features. The occurrence of the strangulation of blood vessels and inflammation can be reduced. An increase in the size of the myofibroblast is not suppressed. The coating solution is produced as a medication is dissolved in a mixed solvent, where the mixed solvent is produced as a polar solvent and a nonpolar solvent are mixed with each other at a certain ratio.

Abstract: The embodiment of the present invention provides an ultrasound diagnostic system, including: an ultrasound diagnosis unit for transmitting ultrasound signals to a target object and receiving ultrasound echo signals to acquire B-mode image signals and Doppler spectrum image signals; a processor for forming at least one B-mode image based on the B-mode image signals and forming a plurality of Doppler spectrum images for a plurality of sample volumes designated on the B-mode image based on the Doppler spectrum image signals; a user input unit for allowing a user to input selection information indicating locations and sizes of the plurality of sample volumes; and an image display unit for displaying at least one B-mode image and the plurality of Doppler spectrum images.

Abstract: The embodiment of the present invention provides an ultrasound diagnostic system, including: an ultrasound diagnosis unit for transmitting ultrasound signals to a target object and receiving ultrasound echo signals to acquire B-mode image signals and Doppler spectrum image signals; a processor for forming at least one B-mode image based on the B-mode image signals and forming a plurality of Doppler spectrum images for a plurality of sample volumes designated on the B-mode image based on the Doppler spectrum image signals; a user input unit for allowing a user to input selection information indicating locations and sizes of the plurality of sample volumes; and an image display unit for displaying at least one B-mode image and the plurality of Doppler spectrum images.