Abstract: This disclosure relates to a method of preventing or treating a recurrence of acute otitis media in a subject at risk comprising administering a therapeutically effective amount of a composition, at least once to the subject. The composition administered comprises at least one immunogenic polypeptide selected from the group consisting of Streptococcus pneumoniae PhtD, PhtE, PcpA, LytB and detoxified pneumolysin.
Type:
Grant
Filed:
December 2, 2011
Date of Patent:
April 17, 2018
Assignee:
SANDFI PASTEUR LIMITED
Inventors:
Michael Pichichero, Martina Ochs-Onolemhemhen