Abstract: Methods of making cholic acid derivatives, particularly ursodeoxycholic acid, tauroursodeoxycholic acid, 7-ketolithocholic acid, obeticholic acid, their carboxylate salts and carboxylate esters, and starting materials and intermediates therefor.
Type:
Grant
Filed:
August 11, 2021
Date of Patent:
July 12, 2022
Assignee:
Sandhill One, LLC
Inventors:
J. Gregory Reid, Jayachandra P Reddy, Bernhard J. Paul, Sk Samad Hossain