Abstract: Described herein are compounds that modulate the activity of TNAP. In some embodiments, the compounds described herein inhibit TNAP. In certain embodiments, the compounds described herein are useful in the treatment of conditions associated with hyper-mineralization.
Type:
Application
Filed:
February 21, 2013
Publication date:
January 8, 2015
Applicant:
Sanford- Burnham Medical Reseach Institute
Inventors:
Anthony B. Pinkerton, Russell Dahl, Nicholas D.P. Cosford, Jose Luis Millan