Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
Type:
Grant
Filed:
May 10, 2004
Date of Patent:
July 17, 2007
Assignee:
Sanifo Pasteur Limited
Inventors:
Michel Henri Klein, Run-Pan Du, Mary Elizabeth Ewasyshyn