Abstract: Waste disposal device including a housing defining a waste compartment for receiving enclosed waste, flexible tubing received in the housing and which operatively receives waste therein, a retention mechanism for holding a quantity of waste received in a length of the tubing and a rotation mechanism for rotating the retention mechanism when the quantity of waste is held thereby and while a remaining length of the tubing is rotationally held stationary in order to twist the length of tubing receiving the waste and enclose the held quantity of waste. The compartment in the housing receives the enclosed waste. The waste is thus rotated while the cartridge is held against rotation thereby enabling the formation of the twist above the waste to enclose or encapsulate the waste. A pushing mechanism may be provided on a cover of the device to push the waste into engagement with the retention mechanism.