Abstract: The present invention relates to sanitization devices and methods. More particularly, the invention relates to devices and methods that significantly reduce or eliminate germs, bacteria and/or other microorganisms from objects such as bags, purses, footwear or other objects, as well as bare feet, hands, paws, hooves or other anatomical surfaces, which come into contact with them. The device and method uses germicidal radiation which exposes only the areas of the object that come into applied contact with the device. The device contains an array of individual cells which are configured to turn on and off sanitizing radiation. The devices may be interconnected to fill a large area such as a lobby, the floor of a hospital and the like.