Patents Assigned to Sanofi-Aventis Deutschland GmbH
  • Patent number: 11071832
    Abstract: An injection device comprising: a housing arranged to contain a medicament cartridge; a needle holder holding an injection needle; a generally tubular needle sleeve fixed with respect to the needle holder and axially movable with respect to the housing; and a gear assembly comprising a rotary gear fixed to the needle holder, a first gear rack disposed on the needle sleeve and a second gear rack disposed on the housing, wherein the gear assembly is arranged so that movement of the needle sleeve in a proximal axial direction causes movement of the needle holder in the proximal axial direction.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: July 27, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Marc Schader, Michael Helmer, Peter Nober
  • Patent number: 11065389
    Abstract: An assembly for a drug delivery device is presented. The assembly comprises a housing and a piston rod having a longitudinal axis, a distal end and a proximal end. The piston rod further comprises a piston rod interaction feature, and a piston rod guide being movable with respect to the piston rod, the piston rod guide further comprising a guide interaction feature corresponding to the piston rod interaction feature, the piston rod guide being movable with respect to the piston rod to switch between a first state and a second state of the assembly, the second state being different from the first state.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: July 20, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Blancke, Axel Teucher, Michael Jugl, Christiane Schneider
  • Patent number: 11058819
    Abstract: An auto-injector device comprises a stopper for expelling a medicament out of a medicament reservoir; a driving element which has a first configuration and a second configuration and is configured to change shape from the first configuration to the second configuration when the temperature of the driving element is raised above a shape change temperature, so as to drive the stopper of the syringe mechanism through the medicament reservoir; and a heating mechanism configured to actively heat the driving element. The heating mechanism is a chemical heating element configured to generate heat through an exothermic process or comprises a fluid reservoir for retaining a fluid; a heater configured to heat the fluid in the fluid reservoir; a pump configured to expel the fluid out of the fluid reservoir; and a connecting conduit arranged to carry the fluid from the fluid reservoir to the driving element.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: July 13, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Wendland, Michael Harms
  • Patent number: 11058825
    Abstract: The present disclosure relates to a cap for an injection device. The injection device comprises a body for holding a syringe having a needle extending from an end thereof. The cap is removably attachable to the body. The cap comprises an actuator and a needle shield to cover said needle. The cap further comprises a coupling between the actuator and the needle shield. The coupling is configured such that when the cap is attached to the body of an injection device axial movement of the actuator away from the body causes rotation of the needle shield relative to the body.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: July 13, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Wendland, Michael Harms
  • Patent number: 11062799
    Abstract: The invention relates to an apparatus (2, 3), comprising a mating unit (20-1, 20-2) for releasably attaching the apparatus (2) to a medical device (1) or for releasably receiving at least a part of the medical device (1). The apparatus (2, 3) further comprises one or more optical sensors (25, 26) and/or one or more acoustical sensors (27) for determining information related to a condition and/or use of the medical device (1). The invention further relates to a system comprising such an apparatus (2, 3) and such a medical device (1), to a method (500, 600, 700) and a computer program (61) for determining information related to a condition and/or use of such a medical device (1), and to a computer-readable medium (60) storing such a computer program (61).
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: July 13, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Schabbach, Amit Kohli
  • Patent number: 11058827
    Abstract: A shroud lock for locking a position of a needle shroud relative to a housing of an autoinjector, includes a shroud beam arranged on the needle shroud and biased radially outwards, a stop arranged within the housing, a recess arranged proximal of the stop, and a cap coupled to the housing and adapted to prevent distal translation of the needle shroud relative to the housing. At least a portion of the shroud beam is within the recess when the cap is in place and, the shroud beam abuts the stop after the needle shroud is locked relative to the housing of the autoinjector. The disclosure further relates to an autoinjector and to a method for assembling such an autoinjector.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: July 13, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Carsten Mosebach, Thomas Mark Kemp
  • Patent number: 11052200
    Abstract: A cap (120) for a drug delivery device (1) having a distal end (121) and a proximal end (122); the cap (120) having an opening at the proximal end and further comprising an outer cap element (130) and an inner cap element (131) being located inside the outer cap element (130), the inner cap element (131) comprising a deformable region (151) and a cap snap means (149); wherein the deformable region (151) of the inner cap element (131) is deformable into a gap (143) between the inner cap element (131) and the outer cap element (130).
    Type: Grant
    Filed: August 26, 2014
    Date of Patent: July 6, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: David Aubrey Plumptre
  • Patent number: 11045610
    Abstract: The disclosure refers to a grasper for a needle sheath removably arranged over a needle, wherein the grasper comprises a grasping carrier formed of a sheet and multiply bent along a plurality of longitudinal fold edges to form a plurality of carrier portions, wherein more than one of the plurality of carrier portions comprises a respective barb projecting from the surface of the carrier portion. The disclosure further refers to a cap and an autoinjector and a method of producing a grasper.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: June 29, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Thomas Mark Kemp, Louise Hodgson, George Sykes
  • Patent number: 11040151
    Abstract: The present disclosure relates to an injection device. The injection device comprises a body for holding a syringe that has a needle at one end and a cap that is removably attached to the body. The cap has a needle shield to cover said needle. The injection device further comprises an actuator member and a translating member. The actuator member is pivotally coupled to one of the cap or body. The translating member is connected to the actuator member and is configured such that pivotal movement of the actuator member relative to said one of the cap or body causes movement of the translating member relative to the body to urge the needle shield away from the body.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: June 22, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Wendland, Michael Harms
  • Patent number: 11033674
    Abstract: A packaging assembly includes a case configured to hold at least one injection device for delivering a medicament and a mounting attachment configured to be attached to the case. The case includes one or more magnets for attaching the mounting attachment to the case and an external face of the case is formed having a recess configured to receive at least part of the mounting attachment.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: June 15, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Hardy Kietzmann, Fred Luck, Stefan Riebel
  • Patent number: 11033683
    Abstract: A medicament injection device comprising: a needle holder holding a needle, a pivotable cartridge holder, the pivotable cartridge holder being pivotable from an open state to a closed state, wherein the pivotable cartridge holder is arranged to receive a medicament cartridge in the open state, and wherein the needle holder is axially movable towards the pivotable cartridge holder when the pivotable cartridge holder is in the closed state.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: June 15, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Helmer, Winfried Huthmacher
  • Patent number: 11033687
    Abstract: An injection device for dispensing of a liquid medicament is disclosed. The device includes an elongated housing extending in an axial direction to accommodate a cartridge, a drive member axially displaceable inside the housing and being in sealed engagement with a side wall of the housing, wherein the drive member has an abutment face to axially abut with a proximal end of a barrel of the cartridge to displace the cartridge from the undeployed position towards the deployed position, wherein the drive member has an outlet located distally from the sealed engagement and further has an inlet located proximally from the sealed engagement, wherein the inlet and the outlet are in flow connection with each other via a flow path extending through the drive member and wherein at least one flow restrictor is arranged across or in the flow path.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: June 15, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Christian Nessel, Christian Dexheimer, Florian Hammen
  • Patent number: 11033688
    Abstract: An injection device comprises a housing containing a cartridge, a needle holder including an injection needle, and a cap. The cap is removably engaged with the housing. The injection device also comprises a translating mechanism configured such that linear distal movement of the cap causes proximal movement of the needle holder such that the injection needle pierces the cartridge.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: June 15, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Helmer, Marc Schader, Peter Nober
  • Patent number: 11028123
    Abstract: The present invention relates to a method for the synthesis of a polypeptide comprising a pre-determined amino acid sequence. The method according to the invention comprises coupling cycles of coupling an N-terminally protected amino acid building block C-terminally at an unprotected N-terminal amino group of an amino acid chain, wherein at least one coupling cycle comprises a coupling step (a), a capping step (b), and a de-protecting step (c).
    Type: Grant
    Filed: April 10, 2019
    Date of Patent: June 8, 2021
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Bernd Henkel, Tobias Metzenthin, Manfred Gerken, Wolfgang Fiedler
  • Patent number: 11027068
    Abstract: The disclosure relates to a syringe support for supporting an axial position of a syringe relative to a housing of an autoinjector. The syringe support includes a supporting beam arranged on the syringe support and biased radially inwards. The supporting beam is adapted to axially bias the syringe in a distal direction within the housing. The disclosure further relates to an autoinjector.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: June 8, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Carsten Mosebach, Thomas Mark Kemp
  • Patent number: 11020533
    Abstract: A data collection device for attachment to an injection device, such as an injector pen, includes a sensor arrangement to detect movement of a movable component of the injection device relative to the data collection device during delivery of a medicament by the injection device, and a processor arrangement configured to, based on said detected movement, determine a medicament dosage administered by the injection device. The processor arrangement may monitor the time that has elapsed since the medicament dosage was administered, and control a display to show the medicament dosage and elapsed time to provide a memory aid to the user. In an example embodiment, the sensor arrangement includes an optical encoder and the movable component includes a plurality of light barrier formations. The movable component may be a number sleeve that provides a visual indication of a dose programmed into the injection device.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: June 1, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Frank Erbstein, Paul Richard Draper, Robert Frederick Veasey, David Aubrey Plumptre, Joseph Butler
  • Patent number: 11020529
    Abstract: In one aspect the present disclosure relates to a sensor for measuring at least one physical or chemical parameter of a cartridge filled with a liquid substance. In a further aspect the disclosure relates to a drug delivery device equipped with such a sensor, wherein the sensor includes a planar flexible foil having a first section and having a second section separated from the first section, at least one measurement electrode located on the flexible foil, wherein the flexible foil is wrappable into a wrapped configuration in which the foil forms at least a first wrap with an inner diameter that is equal to or larger than an outer diameter of the cartridge, wherein in the wrapped configuration the first section and the second section at least partially overlap, at least one fastener located in one of the first and second section and configured to attach to the other one of the first and second sections for keeping the flexible foil in the wrapped configuration.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: June 1, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Schabbach, Christian Nessel, Daniel Auernhammer, Beate Franke, Francisco Soares
  • Patent number: 11017891
    Abstract: A medical device data management unit includes a data storage and a processor. The data storage stores multiple measurement values of a physiological parameter of a user including a blood glucose level, multiple applied medicament dose values, time information associated with the multiple measurement values of the physiological parameter and one or more target ranges of the physiological parameter. The processor can determine a suggestion for a subsequent medicament dose value, check a prior suggestion and adjust the suggestion based on other measured values. The data management unit can be included in a medical device. The instructions to operate the data management unit can be encoded on a computer-readable medium.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: May 25, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Andrew Tubb
  • Patent number: 11016080
    Abstract: The present invention refers to a medical device (100) comprising: •a measurement unit (110) adapted to measure a value of a physiological parameter, for example a blood glucose level, •a data storage (130) adapted to store ?a plurality of measurement values of the physiological parameter, ?for each measurement value an associated event tag, ?for each measurement value an associated time stamp, ?for each at least one predefined event an associated current time range for tagging preselection, •a processor (140) adapted to ?receive from the measurement unit (110) or from the data storage (130) a new measurement value with an associated time, ?comparing the associated time stamp of the new measurement value with the stored at least one time range for tagging preselection, ?if the time stamp is within one current time range for tagging preselection the corresponding tag of the predefined event is preselected and initiated for user confirmation, ?in case one particular predefined tag of one particular predefined e
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: May 25, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Mario Esser
  • Patent number: RE48593
    Abstract: An auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe with an injection needle, a plunger and a stopper for sealing a syringe barrel and a drive means releasably coupled to the plunger for advancing the syringe in the proximal direction (P) for needle insertion into an injection site and for displacing the dose of medicament (M) into the injection site. The drive means is arranged to be decoupled from the plunger for advancing a needle shroud to a safe position (PS) to surround the injection needle after the injection. According to the invention, the drive means bears against a thrust collar arranged to be releasably coupled to the plunger through a ramped engagement of a first tongue and a first recess so as to rotate the thrust collar on translation in proximal direction (P).
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: June 15, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Yannick Hourmand, Simon Francis Brereton, Matthew Ekman