Abstract: An object of the present invention is to provide a therapeutic agent for pulmonary fibrosis which has high therapeutic effect. The invention provides a therapeutic agent for pulmonary fibrosis which comprises, as an active ingredient, a compound represented by the following formula (I): wherein R represents a linear or branched alkyl group having 1 to 30 carbon atoms, a linear or branched alkenyl group having 2 to 30 carbon atoms, or a linear or branched alkynyl group having 2 to 30 carbon atoms, which may contain a cycloalkane or aromatic ring; X and Y each independently represent an oxygen atom or a methylene group, provide that X and Y do not simultaneously represent a methylene group; and M represents a hydrogen atom or an alkali metal atom.

Abstract: It is an object of the present invention to provide a method for easily producing sodium cyclic phosphatidic acid that can be used as food and drink. According to the present invention, provided is a method for producing sodium cyclic phosphatidic acid, comprising a step of allowing a lyso-type phospholipid to react with phospholipase D in the presence of sodium salts in an aqueous medium, and a step of recovering a precipitate or an upper layer liquid that is generated as a result of addition of ethyl alcohol to the obtained reaction solution.

Abstract: An object t of the present invention is to proroaide crystal of a cyclic phosphonic acid sodium salt (2ccPA) with high purity and excellent storage stability and a method for producing the crystal.

Abstract: To provide a thermal insulating sheet, a sheet for use in a truck bed, and a thermal insulating case having superior easiness to handle while having a high thermal insulation ability. A thermal insulating sheet 1 comprises a laminated member comprising a tarpaulin sheet 10, a plurality of synthetic resin nonwoven fabric sheets 11a, 11b, and polyester canvas 12, with the plurality of synthetic resin nonwoven fabric sheets 11a and 11b being provided between the tarpaulin sheet 10 and the polyester canvas 12. A perimeter the laminated member possesses at least a part where at least the tarpaulin sheet and the polyester canvas are fuse-bonded, and remaining parts where the laminated member is stitched together. The polyester canvas possesses one or more through holes, through which air can enter into and exit out of the laminated member, whereas the tarpaulin sheet does not possess any through holes.

Abstract: To provide a thermal insulating sheet, a sheet for use in a truck bed, and a thermal insulating case having superior easiness to handle while having a high thermal insulation ability. A thermal insulating sheet 1 comprises a laminated member comprising a tarpaulin sheet 10, a plurality of synthetic resin nonwoven fabric sheets 11a, 11b, and polyester canvas 12, laminated in this order, wherein at least the tarpaulin sheet 10 and the polyester canvas 12 are fuse-bonded along at least part of a perimeter of the laminated member, and the laminated member is stitched together along a remaining part of the perimeter of the laminated members. A through hole is formed in the polyester canvas 12.

Abstract: This invention provides a therapeutic agent for arthrosis exerting inhibitory effects on articular cartilage destruction and high therapeutic effects on arthrosis. The invention provides a therapeutic agent for arthrosis which comprises, as an active ingredient, cyclic phosphatidic acid or carbacyclic phosphatidic acid.

Abstract: This invention provides a therapeutic agent for arthrosis exerting inhibitory effects on articular cartilage destruction and high therapeutic effects on arthrosis. The invention provides a therapeutic agent for arthrosis which comprises, as an active ingredient, cyclic phosphatidic acid or carbacyclic phosphatidic acid.

Abstract: A packaging container comprises a container body an upper part opening of which performs as an exit, a seal lid sealing the exit of the container body, and an outer lid openably and closably covering the container body. A commercial label is adhered to an outer surface of the outer lid. The outer lid is attached to the container body openably and closably through the label. The packaging container can store unused pieces of sterilized cotton with a tight seal after a user peels the seal lid, and allows the user to easily and conveniently take out the pieces.

Abstract: A packaging container comprises a container body an upper part opening of which performs as an exit, a seal lid sealing the exit of the container body, and an outer lid openably and closably covering the container body. A commercial label is adhered to an outer surface of the outer lid. The outer lid is attached to the container body openably and closably through the label. The packaging container can store unused pieces of sterilized cotton with a tight seal after a user peels the seal lid, and allows the user to easily and conveniently take out the pieces.

Abstract: A disposable sanitary mask comprises a covering panel section adapted to cover the wearer's nose and mouth and a pair of ear-looping panel sections which are respectively formed of nonwoven fibrous fabric. The covering panel section has a central rigid region formed vertically extending across a front surface thereof and side rigid regions defined vertically extending across the front surface thereof, a rigidity of these regions being higher than that of the remaining region of the covering panel section. Therefore, the mask can keep at least the covering panel section from losing its shape.

Abstract: A pharmacological composition for percutaneous administration to a human patient comprises a pharmacologically effective amount of eperisone, a salt thereof, tolperisone or a salt thereof, a water-swellable crosslinked polyvinylpyrrolidone and a base carrier, and exhibits improved percutaneous absorption.

Abstract: (A) a diacylated dopamine derivative represented by the formula (I): ##STR1## wherein R.sup.1 represents an alkyl group having 3 to 7 carbon atoms, a cycloalkyl group having 3 to 6 carbon atoms, substituted or unsubstituted phenyl group or a substituted or unsubstituted nitrogen-containing heterocyclic group; and R.sup.2 represents a hydrogen atom or a lower alkyl group; or a salt thereof; and(B) one or more compounds selected from lactic acid esters, fatty acid monoglycerides and higher alcohols; optionally together with(C) an unsaturated fatty acid monohydric alcohol ester. This preparation has a sustained effect, a high skin permeability and a low skin irritativeness.

Abstract: A pharmaceutical preparation for the percutaneous administration comprises eperisone or tolperisone, including salts thereof, and a monoglyceride of an aliphatic acid having 8 to 12 carbon atoms or/and an ester of lactic acid with an aliphatic alcohol having 12 to 18 carbon atoms. It is improved in the percutaneous absorption.

Abstract: A pharmaceutical preparation for the percutaneous administration comprises eperisone or tolperisone, including salts thereof, and a monoglyceride of an aliphatic acid having 8 to 12 carbon atoms or/and an ester of lactic acid with an aliphatic alcohol having 12 to 18 carbon atoms. It is improved in the percutaneous absorption.

Abstract: A pharmaceutical composition comprises (a) a pharmacologically effective amount of bunazosin or a pharmacologically acceptable salt thereof and (b) a monoglyceride of a fatty acid having 8 to 12 carbon atoms and/or a lactic acid ester of an aliphatic alcohol having 12 to 18 carbon atoms and is improved in percutaneous administration.

Abstract: A process for improving the qualities of paper which comprises making co-exist (a) a water-soluble polymer containing hydrazide group or its adduct with a water-soluble inorganic salt of an alkaline earth metal and (b) a heavy metal ion capable of chelating with the polymer or its adduct in a pulp slurry in paper making. The use of the water-soluble polymer or its adduct in combination with the heavy metal ion improves markedly the paper strength, the retention of sizing agents and the retention of fillers at a pH value around neutrality.

Abstract: A bonding composition for incombustible fibrous materials comprising (a) a water-soluble polymer containing hydrazide groups or its adduct with a water-soluble alkaline earth metal salt of an inorganic acid and (b) a heavy metal ion capable of forming chelate with the water-soluble polymer or its adduct. The bonding composition is employed as bonding agents to prepare incombustible sheet materials from incombustible fibrous materials by adding the components (a) and (b) to an aqueous dispersion of the fibrous materials and forming sheets or by forming wet or dry sheets containing the component (b) and then making the component (a) contain in the sheets. The bonding composition has excellent bonding effect and the polymer itself becomes incombustible, so incombustible sheet materials having excellent strength can be economically obtained.

Abstract: At least one cylinder driven at a constant speed is contained in a casing and a dial plate mounted on the casing is provided with a window extending in the direction of the cylinder. The upper edge of the window is marked with digits. The outer periphery of the cylinder is divided into two sections by a line inclined a definite angle with respect to the axis of the cylinder, and the two areas are coloured by different colours. The inclined line cooperates with the digits to display time. When two or three cylinders are used it is possible to display hours, minutes and seconds.