Abstract: A method of preventing or treating diabetic retinopathy is disclosed including administering to a mammal a therapeutically effective amount of an inhibitor of retinal pericyte apoptosis. Also disclosed is a pharmaceutical composition which treats and/or prevents diabetic retinopathy comprising as an active agent a therapeutically effective amount of at least one inhibitor of retinal pericyte apoptosis and a pharmaceutically acceptable carrier.
Type:
Application
Filed:
April 23, 2003
Publication date:
November 20, 2003
Applicants:
Merck Sante, a corporation of France, INSERM, a corporation of France
Inventors:
Marc Lecomte, Ulriche Denis, Clarisse Paget, Nicolas Wiernsperger, Michel Lagarde
Abstract: A method of disposing of salt-containing dusts from incinerator plants by mixing salt-containing dusts, having approximately 1% or less of lime with cement and water. The amount of cement in the mixture is between 3% and 25% of the total mixture. The amount of hydrothermally reactive powdered components is not less than 8% of the total mixture. The mixture is compacted into discrete compacts, and hardened in an autoclave by saturated steam with a pressure of at least 1 bar to form stable compacts.
Type:
Grant
Filed:
October 17, 1990
Date of Patent:
September 29, 1992
Assignee:
Sante Corporation
Inventors:
Werner Roesky, Dieter Deffner, Manfred Wolter
Abstract: For the disposal of salt-containing dusts of incinerator plants, with addition of water the salt-containing dusts are intensively mixed with other waste materials, such as ashes and fly ashes from thermal power plants fired with hard coal or brown coal, waste materials from foundries containing quartz sands and waste materials from calcium carbide production, the mixture containing at least 8% hydrothermally reactive calcium oxide or equivalent amounts of other hydrothermally reactive calcium compounds and the water addition being so rated that an optimum compacting is possible and the mixture is thereafter processed by compacting to give stable firm compacts and the compacts subsequently hardened in an autoclave by saturated steam at a pressure of at least 1 bar.
Type:
Grant
Filed:
April 18, 1989
Date of Patent:
July 17, 1990
Assignee:
Sante Corporation
Inventors:
Werner Roesky, Dieter Deffner, Manfred Wolter