Patents Assigned to SANTERSUS AG
  • Method and device for removal of circulating cell free DNA
    Patent number: 12053567
    Abstract: The invention provides apheresis devices and their use for substantial removal of all types of cfDNA for treatment of various diseases and during perfusion of an organ and/or anatomical cavity, to limit the negative effects of circulating cfDNA during organ transplantation and thus improve the quality and survival of transplanted organs, and reduce unfavorable transplantation outcomes such as transplant dysfunction, ischemia-reperfusion injury, graft rejection, and organ failure.
    Type: Grant
    Filed: October 21, 2022
    Date of Patent: August 6, 2024
    Assignee: SANTERSUS AG
    Inventors: Kirill Surkov, Andrew Aswani
  • METHOD FOR ISOLATING AND ANALYZING CELL FREE DNA
    Publication number: 20240052334
    Abstract: The invention provides methods of detecting substantially all types of cell free DNA (cfDNA) in biological samples, including nucleosome-bound cfDNA, exosome-bound cfDNA and unbound cfDNA (including double stranded DNA (dsDNA), single stranded DNA (ssDNA) and oligonucleotides), for diagnosis, monitoring and treatment of diseases caused by, or correlated with, increased levels of cfDNA.
    Type: Application
    Filed: October 2, 2020
    Publication date: February 15, 2024
    Applicant: SANTERSUS AG
    Inventors: Kirill SURKOV, Simon TALLETT, Andrew ASWANI
  • Method and device for purification of blood from circulating cell free DNA
    Patent number: 11771812
    Abstract: The invention provides apheresis devices and their use for removal of substantially all types of cell free DNA (cfDNA) in patients' blood, including nucleosome-bound cfDNA, exosome-bound cfDNA and unbound cfDNA (including double stranded DNA (dsDNA), single stranded DNA (ssDNA) and oligonucleotides), to limit the negative effects of the circulating cfDNA and to treat various diseases.
    Type: Grant
    Filed: March 15, 2023
    Date of Patent: October 3, 2023
    Assignee: SANTERSUS AG
    Inventor: Kirill Surkov
  • Method and device for purification of blood from circulating cell free DNA
    Patent number: 11771811
    Abstract: The invention provides apheresis devices and their use for removal of substantially all types of cell free DNA (cfDNA) in patients' blood, including nucleosome-bound cfDNA, exosome-bound cfDNA and unbound cfDNA (including double stranded DNA (dsDNA), single stranded DNA (ssDNA) and oligonucleotides), to limit the negative effects of the circulating cfDNA and to treat various diseases.
    Type: Grant
    Filed: January 3, 2023
    Date of Patent: October 3, 2023
    Assignee: SANTERSUS AG
    Inventor: Kirill Surkov
  • Method and device for purification of blood from circulating cell free DNA
    Patent number: 11724015
    Abstract: The invention provides apheresis devices and their use for removal of substantially all types of cell free DNA (cfDNA) in patients' blood, including nucleosome-bound cfDNA, exosome-bound cfDNA and unbound cfDNA (including double stranded DNA (dsDNA), single stranded DNA (ssDNA) and oligonucleotides), to limit the negative effects of the circulating cfDNA and to treat various diseases.
    Type: Grant
    Filed: September 17, 2018
    Date of Patent: August 15, 2023
    Assignee: SANTERSUS AG
    Inventor: Kirill Surkov
  • METHOD AND DEVICE FOR PURIFICATION OF BLOOD FROM CIRCULATING CELL FREE DNA
    Publication number: 20230218809
    Abstract: The invention provides apheresis devices and their use for removal of substantially all types of cell free DNA (cfDNA) in patients' blood, including nucleosome-bound cfDNA, exosome-bound cfDNA and unbound cfDNA (including double stranded DNA (dsDNA), single stranded DNA (ssDNA) and oligonucleotides), to limit the negative effects of the circulating cfDNA and to treat various diseases.
    Type: Application
    Filed: January 3, 2023
    Publication date: July 13, 2023
    Applicant: SANTERSUS AG
    Inventor: Kirill SURKOV
  • METHOD AND DEVICE FOR PURIFICATION OF BLOOD FROM CIRCULATING CELL FREE DNA
    Publication number: 20230218810
    Abstract: The invention provides apheresis devices and their use for removal of substantially all types of cell free DNA (cfDNA) in patients’ blood, including nucleosome-bound cfDNA, exosome-bound cfDNA and unbound cfDNA (including double stranded DNA (dsDNA), single stranded DNA (ssDNA) and oligonucleotides), to limit the negative effects of the circulating cfDNA and to treat various diseases.
    Type: Application
    Filed: March 15, 2023
    Publication date: July 13, 2023
    Applicant: SANTERSUS AG
    Inventor: Kirill SURKOV
  • METHOD AND DEVICE FOR REMOVAL OF CIRCULATING CELL FREE DNA
    Publication number: 20230201439
    Abstract: The invention provides apheresis devices and their use for substantial removal of all types of cfDNA for treatment of various diseases and during perfusion of an organ and/or anatomical cavity, to limit the negative effects of circulating cfDNA during organ transplantation and thus improve the quality and survival of transplanted organs, and reduce unfavorable transplantation outcomes such as transplant dysfunction, ischemia-reperfusion injury, graft rejection, and organ failure.
    Type: Application
    Filed: October 21, 2022
    Publication date: June 29, 2023
    Applicant: SANTERSUS AG
    Inventors: Kirill SURKOV, Andrew ASWANI
  • METHOD AND DEVICE FOR PURIFICATION OF BLOOD FROM CIRCULATING CELL FREE DNA
    Publication number: 20230098389
    Abstract: The invention provides apheresis devices and their use for removal of substantially all types of cell free DNA (cfDNA) in patients' blood, including nucleosome-bound cfDNA, exosome-bound cfDNA and unbound cfDNA (including double stranded DNA (dsDNA), single stranded DNA (ssDNA) and oligonucleotides), to limit the negative effects of the circulating cfDNA and to treat various diseases.
    Type: Application
    Filed: July 27, 2022
    Publication date: March 30, 2023
    Applicant: SANTERSUS AG
    Inventor: Kirill SURKOV
  • METHOD AND DEVICE FOR PURIFICATION OF BLOOD FROM CIRCULATING CELL FREE DNA
    Publication number: 20230037599
    Abstract: The invention provides apheresis devices and their use for removal of substantially all types of cell free DNA (cfDNA) in patients' blood, including nucleosome-bound cfDNA, exosome-bound cfDNA and unbound cfDNA (including double stranded DNA (dsDNA), single stranded DNA (ssDNA) and oligonucleotides), to limit the negative effects of the circulating cfDNA and to treat various diseases.
    Type: Application
    Filed: July 27, 2022
    Publication date: February 9, 2023
    Applicant: SANTERSUS AG
    Inventor: Kirill SURKOV