Patents Assigned to Sanwa Shoyaku Kabushiki Kaisha
  • Patent number: 5770604
    Abstract: This invention provides novel aconitine compounds of the formula (I) or salt thereof ##STR1## wherein, R.sub.1 is a hydrogen atom or hydroxyl group; R.sub.2 is an acetyloxy group; R.sub.3 is an alkyl having 1-4 carbon atoms; and R.sub.4 is a hydrogen atom, a hydroxyl group, or an acetyloxy group; and antipyretic/analgesic/anti-inflammatory agents containing the compound as an active ingredient which are highly safe and exhibit a powerful analgsic effect and antipyretic/anti-inflammatory activities. The compound is usable alone in painful, pyretic and inflammatory illnesses but its concomitant use with morphine reinforces the analgesic effect of morphine and allows alleviation of morphine side effects through reduction in morphine dosage.
    Type: Grant
    Filed: October 6, 1995
    Date of Patent: June 23, 1998
    Assignee: Sanwa Shoyaku Kabushiki Kaisha
    Inventor: Mitsuo Murayama
  • Patent number: 5514684
    Abstract: Novel aconitine compounds of the formula ##STR1## wherein the symbols are as defined in the description, as well as analgesic/anti-inflammatory agent containing them or salts thereof as active ingredient.
    Type: Grant
    Filed: June 28, 1994
    Date of Patent: May 7, 1996
    Assignee: Sanwa Shoyaku Kabushiki Kaisha
    Inventors: Mitsuo Murayama, Takao Mori
  • Patent number: 5496825
    Abstract: Novel aconitine compounds of the formula ##STR1## wherein the symbols are as defined in the description, as well as analgesic/anti-inflammatory agent containing them or salts thereof as active ingredient.
    Type: Grant
    Filed: June 28, 1994
    Date of Patent: March 5, 1996
    Assignee: Sanwa Shoyaku Kabushiki Kaisha
    Inventors: Mitsuo Murayama, Takao Mori
  • Patent number: 5478833
    Abstract: Novel aconitine compounds of the formula ##STR1## wherein the symbols are as defined in the description, as well as analgesic/anti-inflammatory agent containing them or salts thereof as active ingredient.
    Type: Grant
    Filed: June 28, 1994
    Date of Patent: December 26, 1995
    Assignee: Sanwa Shoyaku Kabushiki Kaisha
    Inventors: Mitsuo Murayama, Takao Mori
  • Patent number: 5478834
    Abstract: Novel aconitine compounds of the formula ##STR1## wherein the symbols are as defined in the description, as well as analgesic/anti-inflammatory agent containing them or salts thereof as active ingredient.
    Type: Grant
    Filed: June 28, 1994
    Date of Patent: December 26, 1995
    Assignee: Sanwa Shoyaku Kabushiki Kaisha
    Inventors: Mitsuo Murayama, Takao Mori
  • Patent number: 5401503
    Abstract: A composition for use in hair growth stimulant and blood circulation stimulant, which contains as active ingredient an extract fraction containing non-aconitine type alkaloidal components which is obtained by extracting Aconitum roots with water or alcohol and removing aconitine type alkaloidal components from the resultant aqueous or alcoholic extract.
    Type: Grant
    Filed: October 25, 1993
    Date of Patent: March 28, 1995
    Assignee: Sanwa Shoyaku Kabushiki Kaisha
    Inventor: Mitsuo Murayama
  • Patent number: 5330983
    Abstract: Analgesic/anti-inflammatory agent containing as active ingredient 14-O-p-chlorobenzoylaconine or a salt thereof. 14-O-p-chlorobenzoylaconine is a novel substance and a compound with high safety which shows an analgesic action on both inflammatory and non-inflammatory pains as well as an anti-inflammatory action. This compound can be used in the treatment of pain-causing diseases, both inflammatory and non-inflammatory, as well as in the treatment of inflammation.
    Type: Grant
    Filed: March 5, 1993
    Date of Patent: July 19, 1994
    Assignee: Sanwa Shoyaku Kabushiki Kaisha
    Inventor: Mitsuo Murayama