Patents Assigned to SAOL INTERNATIONAL DEVELOPMENT LTD.
  • METHOD OF PRODUCING LOCAL NERVE BLOCK BY ADMINISTERING COMPOSITION COMPRISING CYCLODEXTRIN
    Publication number: 20260191899
    Abstract: Disclosed are methods of treating pain by administering cyclodextrin which is majority unoccupied with a guest compound. The cyclodextrin may also be occupied with an inert molecule or agent as a guest, such as proline. Attenuation of pain treatment due to cyclodextrin may be performed by administration of an inert molecule or agent as a guest, such as proline, either before, after or simultaneously with administration of cyclodextrin.
    Type: Application
    Filed: September 2, 2025
    Publication date: July 9, 2026
    Applicant: SAOL INTERNATIONAL DEVELOPMENT LTD.
    Inventors: John DEVANE, David PENAKE, Leonard O’MAHONY, Sharon HAMM, Lopa BHATT
  • METHOD FOR MONITORING AND PREVENTING CLINICALLY SIGNIFICANT KETONE LEVELS IN PATIENTS RECEIVING DICHLOROACETATE CO-ADMINISTERED WITH A CARBOHYDRATE RESTRICTED DIET
    Publication number: 20250369974
    Abstract: Methods of controlling unhealthy levels of beta-hydroxybutyrate during dichloroacetate administration by managing diet are disclosed.
    Type: Application
    Filed: May 23, 2025
    Publication date: December 4, 2025
    Applicants: SAOL INTERNATIONAL DEVELOPMENT LTD., University of Florida Research Foundation, Incorporated
    Inventors: David PENAKE, Susan CLEMENT, John DEVANE, Sharon HAMM, Peter STACPOOLE, Richard WAGNER
  • METHODS OF IMPROVING SURVIVAL AND ELIMINATING TREATMENT-LIMITING TOXICITIES OF DICHLOROACETATE IN PATIENTS WITH PYRUVATE DEHYDROGENASE COMPLEX DEFICIENCY
    Publication number: 20250223628
    Abstract: Methods of improving survival and eliminating treatment-limiting toxicities of dichloroacetate (DCA) in patients with pyruvate dehydrogenase complex deficiency (PDCD).
    Type: Application
    Filed: January 7, 2025
    Publication date: July 10, 2025
    Applicants: SAOL INTERNATIONAL DEVELOPMENT LTD., University of Florida Research Foundation, Incorporated
    Inventors: David PENAKE, Sharon HAMM, Susan CLEMENT, John DEVANE, Peter STACPOOLE
  • Injectable phenol formulations and methods of manufacture
    Patent number: 11083695
    Abstract: Phenol formulations including phenol and an encapsulation agent, such as a cyclodextrin or derivatives thereof, and uses of such formulations.
    Type: Grant
    Filed: January 28, 2021
    Date of Patent: August 10, 2021
    Assignee: SAOL INTERNATIONAL DEVELOPMENT LTD.
    Inventors: Leonard O'Mahony, Sharon Hamm, John Devane, Imran Ahmed, David Penake
  • Injectable phenol formulations and methods of their use
    Patent number: 11083694
    Abstract: Phenol formulations including phenol and an encapsulation agent, such as a cyclodextrin or derivatives thereof, and uses of such formulations.
    Type: Grant
    Filed: January 28, 2021
    Date of Patent: August 10, 2021
    Assignee: SAOL INTERNATIONAL DEVELOPMENT LTD.
    Inventors: Leonard O'Mahony, Sharon Hamm, John Devane, Imran Ahmed, David Penake
  • INJECTABLE PHENOL FORMULATIONS AND METHODS OF THEIR USE
    Publication number: 20210145766
    Abstract: Phenol formulations including phenol and an encapsulation agent, such as a cyclodextrin or derivatives thereof, and uses of such formulations.
    Type: Application
    Filed: January 28, 2021
    Publication date: May 20, 2021
    Applicant: SAOL INTERNATIONAL DEVELOPMENT LTD.
    Inventors: Leonard O'MAHONY, Sharon HAMM, John DEVANE, Imran AHMED, David PENAKE
  • INJECTABLE PHENOL FORMULATIONS AND METHODS OF THEIR USE
    Publication number: 20210145767
    Abstract: Phenol formulations including phenol and an encapsulation agent, such as a cyclodextrin or derivatives thereof, and uses of such formulations.
    Type: Application
    Filed: January 28, 2021
    Publication date: May 20, 2021
    Applicant: SAOL INTERNATIONAL DEVELOPMENT LTD.
    Inventors: Leonard O'MAHONY, Sharon HAMM, John DEVANE, Imran AHMED, David PENAKE
  • Injectable phenol formulations and methods of their use
    Patent number: 10959962
    Abstract: Phenol formulations including phenol and an encapsulation agent, such as a cyclodextrin or derivatives thereof, and uses of such formulations.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: March 30, 2021
    Assignee: SAOL INTERNATIONAL DEVELOPMENT LTD.
    Inventors: Leonard O'Mahony, Sharon Hamm, John Devane, Imran Ahmed, David Penake