Patents Assigned to Sapphire Therapeutics
  • Publication number: 20090143310
    Abstract: The present invention provides a method of stimulating the motility of the gastrointestinal system in a subject in need thereof, wherein the subject suffers from maladies (i.e., disorders, diseases, conditions, or drug- or surgery-induced dysfunction) of the gastrointestinal system, by administering to the subject a ghrelin mimetic, or pharmaceutically acceptable salt thereof. The invention also provides a method of treating a gastrointestinal malady by co-administering a ghrelin mimetic with a laxative, a H2 receptor antagonist, a serotonin receptor agonist, pure or mixed, an antacid, an opioid antagonist, a proton pump inhibitor, a motilin receptor agonist, dopamine antagonist, a cholinergic agonist, a cholinesterase inhibitor, somatostatin, octreotide, or any combination thereof.
    Type: Application
    Filed: November 26, 2008
    Publication date: June 4, 2009
    Applicant: Sapphire Therapeutics
    Inventors: William J. Polvino, Richard Nelson, William R. Mann
  • Publication number: 20080300194
    Abstract: The present invention relates to methods of treating or preventing emesis and improving a subject's ASAS score by administering to the subject an effective amount of a growth hormone secretagogue compound or a pharmaceutically acceptable salt, hydrate or solvate thereof.
    Type: Application
    Filed: April 10, 2008
    Publication date: December 4, 2008
    Applicant: Sapphire Therapeutics, Inc.
    Inventors: William R. Mann, William J. Polvino
  • Publication number: 20080207640
    Abstract: The present invention relates to a method of treating cell proliferative disorders by administering to a subject an effective amount of a growth hormone secretagogue compound or a pharmaceutically acceptable salt, hydrate or solvate thereof.
    Type: Application
    Filed: February 11, 2008
    Publication date: August 28, 2008
    Applicant: Sapphire Therapeutics
    Inventor: William J. Polvino