Patents Assigned to Saramane Pty., Ltd.
  • Malaria merozoite antigen subunit vaccine
    Patent number: 6417341
    Abstract: An immunogenic polypeptide for use in inducing an immune response against Plasmodium infection comprises an amino acid sequence corresponding to a non-full length fragment of the apical membrane antigen 1 (AMA-1) of Plasmodium species which does not include a transmembrane domain thereof, and which is stabilised by folding thereof. Production of the immunogenic polypeptide by expression of a recombinant DNA molecule in a host cell, and methods and compositions using the immunogenic polypeptide are disclosed.
    Type: Grant
    Filed: October 7, 1996
    Date of Patent: July 9, 2002
    Assignee: Saramane Pty., Ltd.
    Inventors: Robin Fredric Anders, Pauline Elizabeth Crewther, Mary Shu Mai Leet, Anthony Neil Hodder, David Pye