Patents Assigned to Saramane Pty., Ltd.
  • Malaria merozoite antigen subunit vaccine
    Patent number: 6417341
    Abstract: An immunogenic polypeptide for use in inducing an immune response against Plasmodium infection comprises an amino acid sequence corresponding to a non-full length fragment of the apical membrane antigen 1 (AMA-1) of Plasmodium species which does not include a transmembrane domain thereof, and which is stabilised by folding thereof. Production of the immunogenic polypeptide by expression of a recombinant DNA molecule in a host cell, and methods and compositions using the immunogenic polypeptide are disclosed.
    Type: Grant
    Filed: October 7, 1996
    Date of Patent: July 9, 2002
    Assignee: Saramane Pty., Ltd.
    Inventors: Robin Fredric Anders, Pauline Elizabeth Crewther, Mary Shu Mai Leet, Anthony Neil Hodder, David Pye
  • Cloning and expression of a rhoptry associated protein of P. falciparum
    Patent number: 5573943
    Abstract: A synthetic or recombinant polypeptide displaying the antigenicity of the 42 kDa rhoptry-associated protein (RAP-2) of P.falciparum or an antigenic fragment thereof, and recombinant DNA molecules, vectors and host cells for the expression thereof.
    Type: Grant
    Filed: April 1, 1993
    Date of Patent: November 12, 1996
    Assignee: Saramane Pty. Ltd.
    Inventors: Allan J. Saul, Ju an A. Cooper, David O. Irving