Patents Assigned to SARCOTEIN DIAGNOSTICS LLC
  • Patent number: 10928396
    Abstract: Provided are methods for screening a subject for cancer. The methods involve obtaining a blood sample from the subject and determining a level of Bridging Integrator 1 (BIN1) isoforms comprising exon 12a in the sample. Optionally, the method involves determining a level of 12a+/13? BIN isoform (comprising exon 12a but lacking exon 13) in the sample. An elevated level of 12a+(e.g., 12a+/13?) BIN1 isoforms in the blood sample indicates the subject has cancer. Also provided are methods for determining efficacy of a cancer therapy in a subject and methods of treating cancer. Isolated antibodies that selectively bind human 12a+ BIN1 are also provided as well as kits for determining 12a+/13? BIN1 isoforms.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: February 23, 2021
    Assignee: SARCOTEIN DIAGNOSTICS, LLC
    Inventors: Darryl Steven Shaw, Neil Gavin Shaw
  • Patent number: 10436800
    Abstract: Provided are methods of determining if a subject has a cardiac disorder or is at risk for developing a cardiac disorder.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: October 8, 2019
    Assignee: SARCOTEIN DIAGNOSTICS, LLC
    Inventors: Darryl Steven Shaw, Neil Gavin Shaw
  • Publication number: 20130324432
    Abstract: Provided are methods for determining skeletal muscle mass in subject. Also provided are methods for diagnosing a neurological condition or disease or a condition or disease associated with reduced skeletal muscle mass in a subject. Further provided are purified antibodies that bind specifically to a BIN1 polypeptide that is expressed specifically in skeletal muscle.
    Type: Application
    Filed: November 7, 2011
    Publication date: December 5, 2013
    Applicant: SARCOTEIN DIAGNOSTICS LLC
    Inventors: Darryl Steven Shaw, Neil Gavin Shaw