Abstract: The present invention is related to a composition comprising a phosphodiesterase inhibitor, such as anagrelide or a salt thereof, for use in the treatment of a solid tumor, such as gastrointestinal stromal tumor (GIST) or a liposarcoma, which express phosphodiesterase 3 enzymes, in a human patient.
Type:
Grant
Filed:
October 17, 2014
Date of Patent:
February 27, 2018
Assignee:
Sartar Therapeutics Ltd
Inventors:
Harri Sihto, Olli-Pekka Pulkka, Olli Kallioniemi, Heikki Joensuu