Patents Assigned to Sartorius Stedim North America Inc.
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Patent number: 9403135Abstract: A mixing container has a wall enclosing a mixing volume, an anchor fixed at the wall of the mixing container inside the mixing volume, and at least one mixing plate movably mounted to the anchor to allow a relative movement of the at least one mixing plate along a stir direction perpendicular to the extension of the mixing plate. Each of the at least one mixing plates is provided with at least one magnet.Type: GrantFiled: March 18, 2014Date of Patent: August 2, 2016Assignee: Sartorius Stedim North America Inc.Inventor: Jonathan Cutting
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Patent number: 9301520Abstract: A system for using freezing, storing and thawing biopharmaceutical materials which includes a holder and a container for holding biopharmaceutical materials therein. The holder has a cavity and the container is received in the cavity. The holder includes a first portion and second portion. The container is received between the first portion and the second portion to connect the container to the holder. The holder includes an interior cradle having a bottom and edges extending from the bottom. The cradle bounds the cavity. An outer rim is connected to the cradle and separated from the cavity. The bottom includes an inner surface facing the cavity receiving the container and an outer surface. The outer surface of the bottom is recessed relative to an outer surface of the outer rim.Type: GrantFiled: December 21, 2007Date of Patent: April 5, 2016Assignee: SARTORIUS STEDIM NORTH AMERICA INC.Inventors: Jonathan Cutting, Isabelle Gay, Eric K. Lee, Nicolas Voute
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Patent number: 9161527Abstract: A system for using freezing, storing and thawing biopharmaceutical materials which includes a holder and a container for holding biopharmaceutical materials therein. The holder has a cavity and the container is received in the cavity. The holder includes a first portion and second portion. The container is received between the first portion and the second portion to connect the container to the holder. The holder includes an interior cradle having a bottom and edges extending from the bottom. The cradle bounds the cavity. An outer rim is connected to the cradle and separated from the cavity. The bottom includes an inner surface facing the cavity receiving the container and an outer surface. The outer surface of the bottom is recessed relative to an outer surface of the outer rim.Type: GrantFiled: June 23, 2011Date of Patent: October 20, 2015Assignee: SARTORIUS STEDIM NORTH AMERICA INC.Inventors: Jonathan Cutting, Isabelle Gay, Eric K. Lee, Nicolas Voute
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Publication number: 20150265985Abstract: A mixing container has a wall enclosing a mixing volume, an anchor fixed at the wall of the mixing container inside the mixing volume, and at least one mixing plate movably mounted to the anchor to allow a relative movement of the at least one mixing plate along a stir direction perpendicular to the extension of the mixing plate. Each of the at least one mixing plates is provided with at least one magnet.Type: ApplicationFiled: March 18, 2014Publication date: September 24, 2015Applicant: Sartorius Stedim North America Inc.Inventor: Jonathan Cutting
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Publication number: 20150265986Abstract: A system for mixing content of a container comprises a container includes an interior mixing element, an exterior drive system and a mixing device comprising an exterior bearing for coupling the exterior drive system to the interior mixing element of the container. The exterior bearing provides a driven non-rotating, nutating motion that drives the interior mixing element of the container so that it performs a mixing motion inside the container.Type: ApplicationFiled: March 21, 2014Publication date: September 24, 2015Applicant: SARTORIUS STEDIM NORTH AMERICA INC.Inventor: Jonathan Cutting
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Patent number: 8863532Abstract: A system for use in freezing, storing and thawing biopharmaceutical materials includes a flexible sterile container means for holding biopharmaceutical material therein and a holder more rigid than said container means. The container means is received in a cavity of the holder and the holder extends along a perimeter of the container means. The holder is fixedly connected to the container means. The holder includes opposing sides defining an opening and the container means extends between the opposing sides of the holder defining the opening. The container means includes a substantially smooth exterior surface extending between the opposing sides.Type: GrantFiled: August 19, 2011Date of Patent: October 21, 2014Assignee: Sartorius Stedim North America Inc.Inventors: Nicolas Voute, Eric K. Lee, Dimitry Yakoushkin
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Patent number: 8651327Abstract: A system for storing biopharmaceutical materials includes a plurality of flexible walls bounding an interior for holding biopharmaceutical materials therein. At least one port is connected to a first wall of the walls and provides fluid communication between the interior and an exterior to allow a draining of the interior. A collapsible conduit includes a plurality of perforations along the conduit. The plurality of perforations is configured to allow flow of the biopharmaceutical materials from the exterior to the interior of the conduit. The conduit has a cross-sectional area transverse to a length of the conduit and the conduit extends from one of the at least one port toward an opposite end of the interior. The conduit is collapsible by the flexible walls and forms a reduced cross-sectional area to allow a flow of the biopharmaceutical materials through and/or along the conduit to the port.Type: GrantFiled: February 9, 2011Date of Patent: February 18, 2014Assignee: Sartorius Stedim North America Inc.Inventors: Jonathan Cutting, Oscar Werner Reif
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Patent number: 8550703Abstract: A system for use in freezing or thawing a biopharmaceutical material includes a container means and a support member. The container means has a receiving cavity receiving the biopharmaceutical material therein. The support member is connected to and supported by the container means. A transmitter is configured to propagate an ultrasonic pulse into the biopharmaceutical material and is located in a support member cavity of the support member. An ultrasonic sensor is configured to sense a reflection of the pulse in the biopharmaceutical material and is located in the support member cavity. A controller is coupled to the transmitter and the sensor. The controller is configured to determine a phase change of the biopharmaceutical material based on the propagation of the pulse by the transmitter and the sense of the reflection by the sensor.Type: GrantFiled: September 27, 2010Date of Patent: October 8, 2013Assignee: Sartorius Stedim North America Inc.Inventor: Jonathan Cutting
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Patent number: 8448457Abstract: A system for use in freezing, thawing, transporting or storing biopharmaceutical materials which includes a container, a holder and plurality of heat transfer members. The container is configured to hold biopharmaceutical materials therein. The holder has a cavity for receiving the container and includes an interior surface bounding the cavity. A plurality of pockets contact outer surfaces of the container and is received in the cavity. Each pocket of the plurality of pockets includes a pocket cavity. A heat transfer member actively controls the temperature of biopharmaceutical materials held in the container and is received in the pocket cavity.Type: GrantFiled: November 23, 2009Date of Patent: May 28, 2013Assignee: Sartorius Stedim North America Inc.Inventors: Jonathan Cutting, Isabelle Gay, Oscar Werner Reif
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Patent number: 8371132Abstract: A system for use in freezing, thawing, transporting or storing biopharmaceutical materials which includes a container, a holder and plurality of heat transfer members. The container is configured to hold biopharmaceutical materials therein. The holder has a cavity for receiving the container and includes an interior surface bounding the cavity. A plurality of pockets contact outer surfaces of the container and is received in the cavity. Each pocket of the plurality of pockets includes a pocket cavity. A heat transfer member actively controls the temperature of biopharmaceutical materials held in the container and is received in the pocket cavity.Type: GrantFiled: March 18, 2010Date of Patent: February 12, 2013Assignee: Sartorius Stedim North America Inc.Inventors: Jonathan Cutting, Isabelle Gay, Oscar Werner Reif
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Patent number: 8177123Abstract: A system for use in storing biopharmaceutical materials includes a holder and a container for holding biopharmaceutical materials therein. The container includes a storage portion and a sampling portion connected to each other by a connecting portion. The holder has a storage cavity receiving the storage portion and a sampling cavity receiving the sampling portion. The holder includes a first portion and second portion. The container is received between the first portion and the second portion to connect the container to the holder. The holder includes an interior storage cradle bounding the storage cavity of the holder. The holder includes an interior sampling cradle bounding the sampling cavity. The sampling cradle is separated from the storage cradle and connected to the storage cradle by a passage receiving the connecting portion connecting the storage portion to the sampling portion. An outer rim of the holder is connected to the cradle and separated from the cavity.Type: GrantFiled: September 24, 2008Date of Patent: May 15, 2012Assignee: Sartorius Stedim North America Inc.Inventors: Nicolas Voute, Jonathan Cutting, Isabelle Gay
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Publication number: 20120073312Abstract: A system for use in freezing or thawing a biopharmaceutical material includes a container means and a support member. The container means has a receiving cavity receiving the biopharmaceutical material therein. The support member is connected to and supported by the container means. A transmitter is configured to propagate an ultrasonic pulse into the biopharmaceutical material and is located in a support member cavity of the support member. An ultrasonic sensor is configured to sense a reflection of the pulse in the biopharmaceutical material and is located in the support member cavity. A controller is coupled to the transmitter and the sensor. The controller is configured to determine a phase change of the biopharmaceutical material based on the propagation of the pulse by the transmitter and the sense of the reflection by the sensor.Type: ApplicationFiled: September 27, 2010Publication date: March 29, 2012Applicant: SARTORIUS STEDIM NORTH AMERICA INC.Inventor: Jonathan Cutting
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Publication number: 20120017609Abstract: A system for use in freezing, storing and thawing biopharmaceutical materials includes a flexible sterile container means for holding biopharmaceutical material therein and a holder more rigid than said container means. The container means is received in a cavity of the holder and the holder extends along a perimeter of the container means. The holder is fixedly connected to the container means. The holder includes opposing sides defining an opening and the container means extends between the opposing sides of the holder defining the opening. The container means includes a substantially smooth exterior surface extending between the opposing sides.Type: ApplicationFiled: August 19, 2011Publication date: January 26, 2012Applicant: SARTORIUS STEDIM NORTH AMERICA INC.Inventors: Nicolas VOUTE, Eric K. LEE, Dimitry YAKOUSHKIN
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Publication number: 20110247349Abstract: A system for using freezing, storing and thawing biopharmaceutical materials which includes a holder and a container for holding biopharmaceutical materials therein. The holder has a cavity and the container is received in the cavity. The holder includes a first portion and second portion. The container is received between the first portion and the second portion to connect the container to the holder. The holder includes an interior cradle having a bottom and edges extending from the bottom. The cradle bounds the cavity. An outer rim is connected to the cradle and separated from the cavity. The bottom includes an inner surface facing the cavity receiving the container and an outer surface. The outer surface of the bottom is recessed relative to an outer surface of the outer rim.Type: ApplicationFiled: June 23, 2011Publication date: October 13, 2011Applicant: SARTORIUS STEDIM NORTH AMERICA INC.Inventors: Jonathan CUTTING, Isabelle GAY, Eric K. LEE, Nicolas VOUTE
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Patent number: 8028532Abstract: A system for use in freezing, storing and thawing biopharmaceutical materials includes a flexible sterile container means for holding biopharmaceutical material therein and a holder more rigid than said container means. The container means is received in a cavity of the holder and the holder extends along a perimeter of the container means. The holder is fixedly connected to the container means. The holder includes opposing sides defining an opening and the container means extends between the opposing sides of the holder defining the opening. The container means includes a substantially smooth exterior surface extending between the opposing sides.Type: GrantFiled: March 6, 2007Date of Patent: October 4, 2011Assignee: Sartorius Stedim North America Inc.Inventors: Nicolas Voute, Eric K. Lee, Dimitry Yakoushkin
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Publication number: 20110120667Abstract: A system for use in freezing, thawing, transporting or storing biopharmaceutical materials which includes a container, a holder and plurality of heat transfer members. The container is configured to hold biopharmaceutical materials therein. The holder has a cavity for receiving the container and includes an interior surface bounding the cavity. A plurality of pockets contact outer surfaces of the container and is received in the cavity. Each pocket of the plurality of pockets includes a pocket cavity. A heat transfer member actively controls the temperature of biopharmaceutical materials held in the container and is received in the pocket cavity.Type: ApplicationFiled: March 18, 2010Publication date: May 26, 2011Applicant: SARTORIUS STEDIM NORTH AMERICA INC.Inventors: Jonathan CUTTING, Isabelle GAY, Oscar Werner REIF