Patents Assigned to Satyanarayama G. Reddy
  • Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
    Patent number: 5401733
    Abstract: The invention relates to the compounds 1,25-dihydroxy-16-ene-24-oxo-cholecalciferol and 1,24,25-trihydroxy-16-ene-cholecalciferol which stimulate differentiation of HL-60 cells, rendering them useful as an agent for the treatment of neoplastic diseases such as leukemia, and also decrease proliferation of human keratinocytes, rendering them useful as an agent for the treatment of hyperproliferative disorders of the skin such as psoriasis.
    Type: Grant
    Filed: October 1, 1993
    Date of Patent: March 28, 1995
    Assignees: Hoffmann-La Roche Inc., Satyanarayama G. Reddy
    Inventors: John A. McLane, Satyanarayama G. Reddy, Milan R. Uskokovic