Abstract: A method of making a contact lens comprising the steps of reacting in a mold a polymerizable formulation comprising at least one fluorine-containing silicone monomer at least one non-fluorine-containing silicone monomer and at least one hydrophilic monomer to form a contact lens, subjecting the contact lens to one or more solvent extraction steps to remove impurities, oligomers and unreacted monomers and hydrate the contact lens, wherein all of the solvent extraction steps are undertaken using an aqueous solvent.

Abstract: A contact lens formed of a composition comprising the reaction product of: A) at least 10 weight percent, based on the total composition weight excluding solvent, of at least one silicone-containing monomer of the formula I: where n is from 1 to 3, m is from 9 to 15, each a independently is C1-4 alkyl, and each b independently is C1-4 alkyl; B) at least 10 weight percent, based on the total composition weight excluding solvent, of 3-methacryloxypropyl tris(trimethylsiloxy)silane; C) N-vinyl pyrrolidone; and D) at least one other non-ionic hydrophilic monomer wherein the combined amount of A) and B) is at least 20 weight percent based on the total composition weight excluding solvent, and wherein the N-vinyl pyrrolidone (NVP) is present in such an amount that the reaction product comprises polyvinyl pyrrolidone (PVP) homopolymer.

Abstract: A contact lens formed of a composition comprising the reaction product of: A) at least 10 weight percent, based on the total composition weight excluding solvent, of at least one silicone-containing monomer of the formula I: where n is from 1 to 3, m is from 9 to 15, each a independently is C1-4 alkyl, and each b independently is C1-4 alkyl; B) at least 10 weight percent, based on the total composition weight excluding solvent, of 3-methacryloxypropyl tris(trimethylsiloxy)silane; C) N-vinyl pyrrolidone; and D) at least one other non-ionic hydrophilic monomer wherein the combined amount of A) and B) is at least 20 weight percent based on the total composition weight excluding solvent, and wherein the N-vinyl pyrrolidone (NVP) is present in such an amount that the reaction product comprises polyvinyl pyrrolidone (PVP) homopolymer.

Abstract: A contact lens formed of a composition comprising the reaction product of: A) at least 10 weight percent, based on the total composition weight excluding solvent, of at least one silicone-containing monomer of the formula I: where n is from 1 to 3, m is from 9 to 15, each a independently is C1-4 alkyl, and each b independently is C1-4 alkyl; B) at least 10 weight percent, based on the total composition weight excluding solvent, of 3-methacryloxypropyl tris(trimethylsiloxy)silane; C) N-vinyl pyrrolidone; and D) at least one other non-ionic hydrophilic monomer wherein the combined amount of A) and B) is at least 20 weight percent based on the total composition weight excluding solvent, and wherein the N-vinyl pyrrolidone (NVP) is present in such an amount that the reaction product comprises polyvinyl pyrrolidone (PVP) homopolymer.

Abstract: A method of making a contact lens comprising the steps of reacting in a mould a polymerisable formulation comprising at least one fluorine-containing silicone monomer at least one non-fluorine-containing silicone monomer and at least one hydrophilic monomer to form a contact lens, subjecting the contact lens to one or more solvent extraction steps to remove impurities, oligomers and unreacted monomers and hydrate the contact lens, wherein all of the solvent extraction steps are undertaken using an aqueous solvent.

Abstract: A method of coating a contact lens comprising the steps of forming an initiator layer on the surface of the contact lens by plasma deposition of at least one initiator monomer and polymerising a propagation monomer onto the initiator layer to form a coating layer of a polymeric material on the contact lens and a method of coating a medical device comprising the steps of forming an initiator polymer layer on at least a part of the medical device by plasma deposition of at least one initiator monomer and polymerising at least one zwitterionic monomer onto the initiator layer to form a coating layer of a polymeric material on the medical device.

Abstract: A contact lens formed of a composition comprising the reaction product of: A) at least 10 weight percent, based on the total composition weight excluding solvent, of at least one silicone-containing monomer of the formula I: where n is from 1 to 3, m is from 9 to 15, each a independently is C1-4 alkyl, and each b independently is C1-4 alkyl; B) at least 10 weight percent, based on the total composition weight excluding solvent, of 3-methacryloxypropyl tris(trimethylsiloxy) silane; C) N-vinyl pyrrolidone; and D) at least one other non-ionic hydrophilic monomer wherein the combined amount of A) and B) is at least 20 weight percent based on the total composition weight excluding solvent, and wherein the N-vinyl pyrrolidone (NVP) is present in such an amount that the reaction product comprises polyvinyl pyrrolidone (PVP) homopolymer.

Abstract: A mould set for making contact lenses comprising a first unitary half mould set comprising a plurality of male mould halves in a first array and a second unitary half mould set comprising a plurality of female mould halves in a second array, wherein the arrays are such as to permit the engagement of respective pairs of male and female mould halves to define a corresponding set of mould cavities therebetween, and to permit engagement of each said female mould half with a different said male mould half by relative rotation of the first and second array about an axis of rotation, such that the male and female mould halves can be engaged in a plurality of different relative orientations. The shape and/or orientation of the male mould halves in the first array, and the female mould halves in the second array is not identical for each mould half in each said array, whereby relative rotation results in the definition of different sets of respective mould cavities.