Abstract: Various embodiments of the invention relate to compositions comprising vitamins, minerals and trace elements, antioxidants, amino acids, probiotics, and other components and methods for using such compositions to treat or prevent diseases associated with oxidative stress, including cardiovascular disease.

Abstract: An oral vaccine for immunization against ETEC-induced diarrhea, comprising inactivated Escherichia coli cells expressing an ETEC colonization factor antigen and dmLT protein adjuvant, wherein the vaccine preferably comprises less than 1013 cells per unit dose.

Abstract: A hair accessory is provided for supplementing and/or replacing hair using a magnetic installation techniques. The magnetic hair accessory may include hair material, magnetic material, a coating, an active face, a neutral face, a score, top piece and/or magnetic band. A method for supplementing and/or replacing hair using a magnetic hair accessory is also provided.

Abstract: A method for increase the presentation of ETEC CS6 antigen on a cell surface, comprising the step of contacting cells expressing said antigen with an aqueous solution comprising 0.6-2.2 percent phenol by weight, such that the presentation of said antigen is increased by at least 100%. A method for the manufacture of a killed whole cell vaccine for immunization against CS6-expressing ETEC. Cells and vaccines obtainable by the above methods.

Abstract: An electrode device for use in delivery of electrical pulses to a desired tissue of a mammal. The electrode device comprises a handle portion comprising first second electrode connections, and first and second needle electrodes comprising a respective first and second attachment end. Each one of the first and second electrode connections is configured with an inner electrode position and an outer electrode position, wherein the inner and outer electrode positions are electrically conducting. Further, each one of the first and second attachment ends is configured with an insulating part configured to electrically insulate one out of the inner electrode position and the outer electrode position when located therein, and configured with an electrically conducting part configured to conduct current supplied to the other one out of the inner electrode position or the outer electrode position when located therein.

Abstract: A system (10) for washing items (12) with purified water alone, comprising a washing machine (11), a water purification apparatus (19), and a reservoir (20) for storing purified water, wherein the water purification apparatus (19) comprises a reverse osmosis device (26) and first and second deionizing materials. The washing machine (11) comprises a container (13) for receiving the items (12) to be washed, and said container (13) is arranged with an inlet connected to the reservoir (20), so that the items (12) are washable inside the container (13) with the purified water. The system (10) further comprises a tank (24) for collecting used water from the container (13), wherein an inlet of the tank (24) is connected to an outlet of the container (13). The system (10) also comprises a sediment filter (28) for filtering off particulate solids from the used water, wherein the sediment filter (28) is arranged between the tank (24) and the water purification apparatus (19).

Abstract: A vascular coupling device for connecting an artificial heart pump to the vascular system of a subject is disclosed. The artificial heart pump may form part of a total artificial heart (TAH). The vascular coupling device comprises a first and a second coupling element, each one of said first and second coupling elements has a first end comprising a resilient coupling portion, a second end comprising a vascular grafting material, and a tubular midsection is arranged between said first and second ends. The vascular coupling device further comprises a coupling plate comprising a first receptor and a second receptor configured and adapted for receiving said resilient coupling portions of the first and second coupling elements.

Abstract: A pulse generating device for delivery of electrical pulses to a desired tissue and configured to be connected to needle electrodes arranged at the desired tissue. The device comprises a determining module configured to determine a primary voltage amplitude of a first pulse and a number of consecutive pulses to be generated. Further, the device comprises a pulse generator configured to generate one or more of the determined number of consecutive pulses such that the generated first pulse has the primary voltage amplitude and that the generated consecutive pulses have a respective voltage amplitude consecutively decreasing between consecutive pulses, whereby an increase in a current value of the generated consecutive pulses above a threshold value is avoided. Furthermore, the device comprises a terminating module configured to terminate generation of the one or more pulses when a value of a total absorbed energy exceeds a threshold value.

Abstract: A method for operating a cargo door of an aircraft. The method comprises, opening the cargo door inwardly in relation to a cargo door opening by pivoting the cargo door to an open position adjacent a ceiling of a cargo space. The cargo door is supported by a door frame during opening of the cargo door. The method further comprises, moving the cargo door in relation to the door frame to a position wherein the cargo door opening is substantially free from the cargo door. The cargo door is supported by a support frame, moveable in relation to the door frame, during this movement. The invention also concerns a device for operating a cargo door of an aircraft.

Abstract: A vascular coupling device (10), comprising a first and a second coupling element (21, 22) wherein each one of said first and second coupling elements (21, 22) has an external surface (23?, 23?) facing an external side, a coupling surface (25?, 25?) facing a coupling side, a central opening (27?, 27?), and a first and a second tubular connecting element (31, 32). Each one of said first and second tubular connecting elements (31, 32) is arranged in a corresponding central opening (27?, 27?) of the first and second coupling elements (21, 22) respectively, and with second open ends (37, 38) protruding through said central openings (27?, 27?) on said external side of each of said first and second coupling elements (21, 22).

Abstract: A system and method for washing items with water includes a water inlet and a container for receiving the items to be washed. The system comprises a water purification apparatus for purifying water introduced through said water inlet to produce purified water. The water purification apparatus comprises at least one filter for filtering off particulate solids, a reverse osmosis device, and at least one deionizing filter. The system further comprises a reservoir for storing purified water produced by the water purification apparatus, said reservoir being connected to said water purification apparatus and said container, so that the items are washable inside the container with the purified water.

Abstract: A device for delivery of electrical pulses to a desired tissue of a mammal. The device comprises a pulse generating device and an electrode device connected to the pulse generating device. The pulse generating device is configured to determine conductance and phase angle values between one electrode and a reference electrode of the electrode device when the electrode device is inserted into the desired tissue and when pulses based on alternating currents having different frequencies are generated between the electrode and the reference electrode. Based on the determined conductance and phase angle values, the pulse generating device is configured to determine the type of tissue the electrode device penetrates, to determine one or more parameters of electrical pulses to be delivered to the desired tissue and to generate the electrical pulses having the determined one or more parameters.

Abstract: A blood pump housing device designed to enclose and protect a total artificial heart when implanted in a subject is disclosed. The blood pump housing device comprises a first and second artificial heart pump receiving part (3a, 3b) configured to receive and partly enclose a first and a second artificial heart pump (20a, 20b) of a total artificial heart (TAH); and a first and second pump actuation enclosing part (4a, 4b) configured to partly enclose a first and second pump actuation means (60a, 60b), said artificial heart pump receiving parts (3a, 3b) and pump actuation means enclosing parts (4a, 4b) are arranged to connect to each other in a leak-free manner.

Abstract: The present disclosure relates to an implantable split sternum prosthesis to facilitate closure of the chest cavity and relieve pain after sternotomy operations. The split sternum prosthesis which after a surgical procedure is placed along the inline incision made in the sternum bone will also facilitate access to the chest cavity for patients in need of repeated surgical operations inside the chest cavity. The split sternum prosthesis comprises two elongated bone attachment plates, a first bone attachment plate and a second bone attachment plate. The first and he second bone attachment plates each have a bone attachment surface and a coupling surface. The first and second bone attachment plates are adapted be coupled together in a very close fit along their coupling surfaces.

Abstract: A blood pumping device is described having at least a first pump and a first pump actuator for inducing a blood flow in a body's circulatory system. The pump has one upper chamber having an inlet channel and one lower chamber having an outlet channel. The upper and lower chambers are separated by a movable valve plane provided with a one-way valve. The pump actuator induces movement of the valve plane in an upward and downward direction between the upper and lower chambers in response to control signals from a control unit. When the valve plane moves in an upward direction, the valve opens allowing a flow of blood from the upper to the lower chamber. The lower chamber is provided with a bag-like portion forcing said flow of blood to make a turn of between 110° to 150° before leaving through the outlet channel.

Abstract: A vascular coupling device for connecting an artificial heart pump to the vascular system of a subject is disclosed. The artificial heart pump may form part of a total artificial heart (TAH). The vascular coupling device comprises a first and a second coupling element, each one of said first and second coupling elements has a first end comprising a resilient coupling portion, a second end comprising a vascular grafting material, and a tubular midsection is arranged between said first and second ends. The vascular coupling device further comprises a coupling plate comprising a first receptor and a second receptor configured and adapted for receiving said resilient coupling portions of the first and second coupling elements.

Abstract: An oral vaccine for immunization against ETEC-induced diarrhea, comprising inactivated Escherichia coli cells expressing an ETEC colonization factor antigen and dmLT protein adjuvant, wherein the vaccine preferably comprises less than 1013 cells per unit dose.

Abstract: A microfluidic assay system including a microfluidic cartridge and an associated microfluidic operator system. The microfluidic cartridge comprises a base part, having a first face with a recess and a foil fixed to the base part for covering the recess and providing a microfluidic cartridge foil face. The base part with the recess and the foil forms a flow channel and a sink in fluid communication with each other. The microfluidic cartridge comprises an inlet opening into the flow channel upstream to the reaction section.

Abstract: A method for increase the presentation of ETEC CS6 antigen on a cell surface, comprising the step of contacting cells expressing said antigen with an aqueous solution comprising 0.6-2.2 percent phenol by weight, such that the presentation of said antigen is increased by at least 100%. A method for the manufacture of a killed whole cell vaccine for immunization against CS6-expressing ETEC. Cells and vaccines obtainable by the above methods.

Abstract: The present invention relates to a method of preparing a strain of sugar fermenting Saccharomyces cerevisiae with capability to ferment xylose, wherein said method comprises different procedural steps. The method comprises mating a first sporulated Saccharomyces cerevisiae strain with a second Saccharomyces cerevisiae haploid strain. Thereafter, screening for mated cells is performed, growing such mated cells, and verifying that mated cells exhibit basic morphology by microscopic inspection. Thereafter, creation of a mixture of the mated cells is performed, subjecting the mixture to continuous chemostat lignocellulose cultivation and obtaining the sugar fermenting Saccharomyces cerevisiae cells with capability to ferment xylose is performed. The invention also comprises strains obtained by said method.