Abstract: An oral vaccine for immunization against ETEC-induced diarrhea, comprising inactivated Escherichia coli cells expressing an ETEC colonization factor antigen and dmLT protein adjuvant, wherein the vaccine preferably comprises less than 1013 cells per unit dose.
Type:
Grant
Filed:
July 1, 2021
Date of Patent:
March 5, 2024
Assignee:
SCANDINAVIAN BIOPHARMA HOLDING AB, C/O ETVAX AB
Inventors:
Ann-Mari Svennerholm, Joshua Tobias, Nils Carlin, Jan Holmgren