Abstract: The invention relates to a test kit for better carrying out a method for detecting biomarkers in human or animal stool, which can serve as an indication of a pathological, particularly a malignant event in the gastrointestinal tract (esophagus, stomach, small bowel, biliary tract, pancreas, and bowel). The invention teaches a novel and more efficient methods, uses and embodiments of a combined rapid test. The combined rapid test cassette used for implementing the test kit and the optimally coordinated reagents thereof contains two lateral flow test strips for the synchronous—in the technical meaning—detection of the biomarkers M2-PK and the biomarker hemoglobin. The test serves as a “dual filter” for diagnosing probands as part of a colon cancer screening program. The test is very cost-efficient and cuts costs in the health system by the examination at an early stage of colon cancer and the consequences thereof.

Abstract: The invention relates to new butane acid derivatives comprising a cyanide group, pharmaceutical compositions containing said butane acid derivatives and the use of said butane acid derivatives in the production of pharmaceutical compositions for treating various illnesses.

Abstract: The invention relates to compounds for modulating the glycolosis enzyme complex and the transaminase complex, to pharmaceutical compositions containing said compounds, and to the uses of said compounds for the production of pharmaceutical compositions for treating different diseases.

Abstract: In order to selectively, qualitatively or/and quantitatively detect the pyruvate kinase isoenzyme of the tumor M2-PK type (tumor M2-PK) which serves as a tumor marker in human and animal feces to detect a malignant process in the gastrointestinal tract, tumor M2-PK is detected in a stool specimen by an immunoassay technique with the aid of at least one antibody which specifically binds tumor M2-PK and does not cross-react with any other pyruvate kinase isoenzyme. A test kit for diagnosing malignant tumor growth in the gastrointestinal tract and in particular in the intestines contains at least one receptor for tumor M2-PK which does not cross-react with any other pyruvate kinase isoenzyme and optionally contains additional reagents that are necessary for carrying out an immunoassay.

Abstract: In order to selectively, qualitatively or/and quantitatively detect the pyruvate kinase isoenzyme of the tumor M2-PK type (tumor M2-PK) which serves as a tumor marker in human and animal feces to detect a malignant process in the gastrointestinal tract, tumor M2-PK is detected in a stool specimen by an immunoassay technique with the aid of at least one antibody which specifically binds tumor M2-PK and does not cross-react with any other pyruvate kinase isoenzyme. A test kit for diagnosing malignant tumor growth in the gastrointestinal tract and in particular in the intestines contains at least one receptor for tumor M2-PK which does not cross-react with any other pyruvate kinase isoenzyme and optionally contains additional reagents that are necessary for carrying out an immunoassay.

Abstract: In order to selectively, qualitatively or/and quantitatively detect the pyruvate kinase isoenzyme of the tumor M2-PK type (tumor M2-PK) which serves as a tumor marker in human and animal feces to detect a malignant process in the gastrointestinal tract, tumor M2-PK is detected in a stool specimen by an immunoassay technique with the aid of at least one antibody which specifically binds tumor M2-PK and does not cross-react with any other pyruvate kinase isoenzyme. A test kit for diagnosing malignant tumor growth in the gastrointestinal tract and in particular in the intestines contains at least one receptor for tumor M2-PK which does not cross-react with any other pyruvate kinase isoenzyme and optionally contains additional reagents that are necessary for carrying out an immunoassay.

Abstract: The invention relates to compounds for the modulation of the glycolysis enzyme complex and of the transaminase complex, pharmaceutical compositions containing such compounds as well as uses of such compounds for preparing pharmaceutical compositions for treating various diseases.

Abstract: The invention relates to compounds for the modulation of the glycolysis enzyme complex and of the transaminase complex, pharmaceutical compositions containing such compounds as well as uses of such compounds for preparing pharmaceutical compositions for treating various diseases.