Patents Assigned to Schering Akiengesellschaft
  • Nucleic acid ligands of tissue target
    Patent number: 5750342
    Abstract: This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to peripheral blood mononuclear cells (PBMC), fibrin clots, and carotid arteries are described.
    Type: Grant
    Filed: May 3, 1995
    Date of Patent: May 12, 1998
    Assignees: NeXstar Pharmaceuticals, Inc., Schering Akiengesellschaft
    Inventors: Andrew Stephens, Dan Schneider, Larry Gold, Ulrich Speck