Abstract: The invention concerns new vitamin D derivatives of general formula (I) a process for their production, their use for production of medicaments, and intermediate products used in the process.
Type:
Grant
Filed:
October 25, 2000
Date of Patent:
July 29, 2003
Assignee:
Schering Aktiengellschaft
Inventors:
Andreas Steinmeyer, Gerald Kirsch, Günter Neef, Katica Schwarz, Ruth Thieroff-Ekerdt, Herbert Wiesinger, Martin Haberey, Marianne Fahnrich
Abstract: The present invention discloses synthetic peptides and antibodies raised thereto wherein the synthetic peptides represent important epitopic sites recognized by monoclonal antibodies which can neutralize IFN-.beta.. Also, the uses of these peptides or antibodies thereto as diagnostics and therapeutics are disclosed.
Abstract: Improved metal complex-containing pharmaceutical agents are described which, as an additive, contain one or more complexing agents and/or one or more weak metal complex(es) or mixtures thereof.
Type:
Grant
Filed:
October 22, 1990
Date of Patent:
March 24, 1992
Assignee:
Schering Aktiengellschaft
Inventors:
Heinz Gries, Ulrich Speck, Hanns-Joachim Weinmann, Hans P. Niendorf, Wolfgang Seifert
Abstract: The side chains of sterols are degraded by fermentation with microorganisms capable of doing so in an improved manner by employing in such fermentations sterol derivatives of the formula ##STR1## wherein n is 1 or 2; R.sub.1 is H or lower alkyl, R.sub.2 is alkyl, whose chain optionally is interrupted by an oxygen atom, or when n is 2, also a hydrogen atom; and R.sub.3 is a sterol side chain.
Type:
Grant
Filed:
July 6, 1977
Date of Patent:
December 18, 1979
Assignee:
Schering Aktiengellschaft
Inventors:
Alfred Weber, Mario Kennecke, Helmut Dahl