Patents Assigned to Schering Aktiengesellschaft (A.G.)
  • Antiandrogenic 17.alpha.-alkyl steroids
    Patent number: 4456600
    Abstract: 17.alpha.-substituted steroids of the formula ##STR1## wherein R.sub.1 is hydrogen, acyl, alkyl, alkenyl, alkyl or alkenyl interrupted by an oxygen atom, cyclopentyl, or tetrahydropyranyl,R.sub.2 is alkyl or alkenyl of 2-6 carbon atoms,X is oxygen or the grouping H(OR.sub.3) wherein R.sub.3 is hydrogen, acyl, alkyl, alkenyl, alkyl or alkenyl interrupted by an oxygen atom, cyclopentyl, or tetrahydropyranyl, upon topical application, display antiandrogenic properties and can be utilized for the treatment of acne, seborrhea, alopecia and hirsutism.
    Type: Grant
    Filed: May 20, 1982
    Date of Patent: June 26, 1984
    Assignee: Schering, Aktiengesellschaft (A.G.)
    Inventors: Rudolf Wiechert, Dieter Bittler, Annerose Schleusener, Manfred Albring
  • Antiandrogenic 17.alpha.-substituted steroids
    Patent number: 4344941
    Abstract: 17.alpha.-substituted steroids of the formula ##STR1## wherein R.sub.1 is hydrogen, acyl, alkyl, alkenyl, alkyl or alkenyl interrupted by an oxygen atom, cyclopentyl, or tetrahydropyranyl,R.sub.2 is alkyl or alkenyl of 2-6 carbon atoms,X is oxygen or the grouping H(OR.sub.3) wherein R.sub.3 is hydrogen, acyl, alkyl, alkenyl, alkyl or alkenyl interrupted by an oxygen atom, cyclopentyl, or tetrahydropyranyl, upon topical application, display antiandrogenic properties and can be utilized for the treatment of acne, seborrhea, alopecia and hirsutism.
    Type: Grant
    Filed: October 20, 1980
    Date of Patent: August 17, 1982
    Assignee: Schering Aktiengesellschaft (A.G.)
    Inventors: Rudolf Wiechert, Dieter Bittler, Annerose Schleusener, Manfred Albring
  • 1,3-Dibenzoic acid esters of 17.alpha.-ethynyl-7.alpha.-methyl-1,3,5(10)-estratriene-1,3,17.beta.-tri ol
    Patent number: 4259325
    Abstract: 1,3-Dibenzoic acid esters of 17.alpha.-ethynyl-7.alpha.-methyl-1,3,5(10)-estratriene-1,3,17.beta.-triol possess strong estrogenic and ovulation-inhibiting activities. As compared to the corresponding diacetic acid ester, these dibenzoic acid esters remain stable over 2-7 months even in the desired, low dosage at a thermal load of up to 60.degree. C.
    Type: Grant
    Filed: April 10, 1979
    Date of Patent: March 31, 1981
    Assignee: Schering Aktiengesellschaft (A.G.)
    Inventors: Klaus Prezewowsky, Hermann Steinbeck, Rudolf Wiechert