Abstract: This invention is directed to lipoxin A4 analogs of the following formula (I) and (II):
wherein R1, R2, R3, R4 and R5 are described herein. These analogs are useful in treating inflammatory and autoimmune disorders in humans. These analogs are also useful in treating pulmonary or respiratory tract inflammation in humans.
Type:
Grant
Filed:
October 22, 2002
Date of Patent:
December 14, 2004
Assignee:
Schering Aktiengesellschft
Inventors:
John G Bauman, William J Guilford, John F Parkinson, Werner Skuballa, Babu Subramanyam