Patents Assigned to Schering Coporation
  • Farnesyl protein transferase inhibitors as antitumor agents
    Patent number: 7557107
    Abstract: Disclosed are novel tricyclic compounds of the formula: and a pharmaceutically acceptable salts or solvates thereof. The compounds are useful for inhibiting farnesyl protein transferase. Also disclosed are pharmaceutical compositions comprising the compounds of formula (I). Also disclosed are uses of the compounds of formula (I) for the manufacture of a medicament for the treatment of cancer.
    Type: Grant
    Filed: August 4, 2004
    Date of Patent: July 7, 2009
    Assignee: Schering Coporation
    Inventors: Hugh Y. Zhu, Alan B. Cooper, Jagdish A. Desai, James J-S Wang, Ronald J. Doll, F. George Njoroge, Viyyoor M. Girijavallabhan