Abstract: Agonists or antagonists of CTACK or Vic chemokines, and various methods of use in dermatological and related applications are provided. In particular, the method makes use of fact that the CTACK or Vic chemokines are specifically capable of inducing movement of a skin cell subset. Moreover, matching of ligand with GPR2 receptor in mammals provides methods of use.
Type:
Application
Filed:
July 2, 2001
Publication date:
October 31, 2002
Applicant:
Schering Corpration, a New Jersey corporation
Inventors:
Wei Wang, Elizabeth R. Oldham, Hortensia Soto, Ying Liu, Susan A. Hudak, Bernhard Homey, Janine M. Morales, Sirid-Aimee Kellermann, Leslie M. McEvoy, Edward P. Bowman, Albert Zlotnik