Abstract: Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
Type:
Grant
Filed:
March 28, 2017
Date of Patent:
August 21, 2018
Assignees:
The University of Tokyo, School Corporation, Azabu Veterinary Medicine Educational Institute
Inventors:
Kenya Honda, Koji Atarashi, Takeshi Tanoue, Masahira Hattori, Hidetoshi Morita