Abstract: An aquatic subunit vaccine comprises an antigenic fusion protein and suitable carrier or adjuvant. The antigenic fusion protein sequence consists from its amino terminus to carboxyl terminus of a receptor binding motif and a translocation domain of Pseudomonas aeruginosa exotoxin A and has the amino acid sequence of SEQ ID No: 8; a viral antigenic protein affecting fish disease; and a signal peptide having the amino acid sequence of SEQ ID No: 10.
Abstract: A subunit vaccine for aquaculture comprises an antigen fusion protein, and appropriate carriers or adjuvants. From amino terminal to carboxyl terminal, the antigen fusion protein comprises domain I and domain II of Pseudomonas aeruginosa exotoxin A; a viral antigenic protein producing a fish disease; and a signal peptide of a protein.