Abstract: Logic elements are provided that permit reductions in layout size and avoidance of hazards. Such logic elements may be included in libraries of logic cells. A logical function to be implemented by the logic element is decomposed about logical variables to identify factors corresponding to combinations of the logical variables and their complements. A pass transistor network is provided for implementing the pass network function in accordance with this decomposition. The pass transistor network includes ordered arrangements of pass transistors that correspond to the combinations of variables and complements resulting from the logical decomposition. The logic elements may act as selection circuits and be integrated with memory and buffer elements.

Abstract: An organoboron route and process for preparation of boron nitride utilizing aerosol assisted vapor phase synthesis (AAVS) wherein organoboron precursors are nitrided in one or two heating steps, and wherein a boron oxide nitride intermediary composition is formed after the first heating step and may be further nitrided to form resultant spheroidal boron nitride powders including spheroidal particles that are smooth, bladed, have protruding whiskers, and are of turbostratic or hexagonal crystalline structure.

Abstract: A digital integrated circuit chip is designed by identifying a logical structure to be implemented. This logical structure is represented in terms of a logical operations, at least 5% of which include selection operations. A determination is made of logic cells that correspond to an implementation of these logical operations.

Abstract: The present invention provides a splint that may be telescopically extendable, coarsely and finely adjustable, and providing a mechanical advantage while being readily transportable. The splint may have two to three telescoping members that nest inside one another when not in use, and may be triangular, rectangular, or circular in cross section. The present invention also provides a single member adjustable splint.

Abstract: According to the invention, a digital design method for manipulating a digital circuit netlist is disclosed. In one step, a first netlist is loaded. The first netlist is comprised of first basic cells that are comprised of first kernel cells. The first netlist is manipulated to create a second netlist. The second netlist is comprised of second basic cells that are comprised of second kernel cells. A percentage of the first and second kernel cells are selection circuits. There is less chip area consumed in the second basic cells than in the first basic cells. The second netlist is stored. In various embodiments, the percentage could be 2% or more, 5% or more, 10% or more, 20% or more, 30% or more, or 40% or more.

Abstract: According to the invention, a digital circuit design embodied in at least one of a structural netlist, a behavioral netlist, a hardware description language netlist, a full-custom ASIC, a semi-custom ASIC, an IP core, an integrated circuit, a hybrid of chips, one or more masks, a FPGA, and a circuit card assembly is disclosed. The digital circuit design includes first and second sub-circuits. The first sub-circuits comprise a first percentage of the digital circuit design and the second sub-circuits comprise a second percentage of the digital circuit design. Each of the second sub-circuits is substantially comprised of one or more kernel circuits. The kernel circuits are comprised of selection circuits. The second percentage is at least 5%. In various embodiments, the second percentage could be at least 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, or 95%.

Abstract: A method for purifying heat shock protein complexes is provided which comprises the steps of adding a solution containing heat shock protein complexes, in which heat shock proteins are associated with peptides, polypeptides, denatured proteins or antigens, to a column containing an ADP matrix to bind the heat shock proteins complexes to the ADP matrix and adding a buffer containing ADP to the column to remove the heat shock protein complexes in an elution product. Additionally a method for synthesizing heat shock protein complexes and purifying the complexes so product is provided which comprises the steps of adding heat shock proteins to an ADP matrix column to bind them to the matrix, adding a solution of peptides, polypeptides, denatured proteins or antigens to the column to bind them to the heat shock proteins as heat shock protein complexes and adding a buffer containing ADP to the column to remove the complexes in all elution product.

Abstract: The invention provides a reagentless assay kit for analyte in a sample comprising a modular affinity assembly including at least one sensor unit comprising a ligand having binding affinity for the analyte (affinity module) operatively associated with a reporter probe (reporter module) responsive to changes in the sensor unit induced by analyte/receptor complex formation by transduction of a characteristic detectable signal. Assays employing the modular assembly are also provided.

Abstract: Cyclic peptides inhibit LFA-1 interaction with ICAM-1 and are useful in treatment of hematopoietic neoplasms and in adjunct therapy in prevention of retinoic acid syndrome and diseases involving emigration of leukocytes into organ tissue.

Abstract: An apparatus for drawing and supplying multiple samples for rapid processing in flow cytometry. The apparatus comprises a reciprocating valve and at least one syringe. The invention is also a method for rapidly processing multiple samples in flow cytometry using the apparatus.

Abstract: A new and useful technique for growing an epilayer onto a substrate is provided. An epilayer is grown on a substrate by (a) providing a patterned substrate comprising a plurality of isolated nanoscale nucleation sites, and (b) growing an epilayer selectively on the nanoscale nucleation sites, in a manner which localizes strain at the substrate-epilayer interface, and enables strain to reduce as the thickness of the epilayer increases.

Abstract: A CMOS circuit formed in a semiconductor substrate having improved immunity to total ionizing dose radiation, improved immunity to radiation induced latch up, and improved immunity to a single event upset. The architecture of the present invention can be utilized with the n-well, p-well, or dual-well processes. For example, a preferred embodiment of the present invention is described relative to a p-well process wherein the p-well is formed in an n-type substrate. A network of NMOS transistors is formed in the p-well, and a network of PMOS transistors is formed in the n-type substrate. A contact is electrically coupled to the p-well region and is coupled to first means for independently controlling the voltage in the p-well region. Another contact is electrically coupled to the n-type substrate and is coupled to second means for independently controlling the voltage in the n-type substrate.

Abstract: Continuously tunable and precisely wavelength-switchable fiber lasers combine fiber Bragg gratings and the transmissive filtering properties of high finesse fiber Fabry-Perot filters. This laser arrangement adapts to multiple wavelength ranges based on the selections of fiber Bragg grating and gain medium and their arrangement to create a wavelength-modulatable and simultaneously rapidly wavelength-switchable narrow linewidth all-fiber laser design. This laser arrangement further results in narrow-linewidth outputs with fast switching speeds between the selected wavelengths.

Abstract: The present invention relates to catalysts in mesoporous structures. In a preferred embodiment, the invention comprises a method for encapsulating a dispersed insoluble compound in a mesoporous structure comprising combining a soluble oxide precursor, a solvent, and a surfactant to form a mixture; dispersing an insoluble compound in the mixture; spray-drying the mixture to produce dry powder; and calcining the powder to yield a porous structure comprising the dispersed insoluble compound.

Abstract: An improved highly doped waveguide is provided which comprises a waveguide employing an Er dopant and Pr sensitizer ions. The present invention also provides a method of efficient coupling from an optical source into a waveguide using a rotated optical element.

Abstract: The present invention relates generally to electro-optically active waveguide segments, and more particularly to the use of a selective voltage input to control the phase, frequency and/or amplitude of a propagating wave in the waveguide. Particular device structures and methods of manufacturing are described herein.

Abstract: Novel ion mirrors comprising, in a preferred embodiment, three cylinders, rectangles or truncated cones to improve the resolving power in the time-of-flight mass spectrometers over broad ion kinetic energy ranges. The achieved electric field is non-linear along the mirror axis and relatively homogeneous in the mirror off-axis directions. Combined with dimension optimization, in a preferred embodiment, the adjustment of only two parameters of element voltages can yield preferred electric field distribution to fit different ion optical systems.

Abstract: An improved method and apparatus for mode-locking a fiber laser at a pre-selected frequency wherein a doped fiber segment contains a narrowband FBG and an electro-optically tuned FBG, thereby making obsolete the need for an EOM to modulate the laser's wavelength. The present invention also provides a method and apparatus for mode-locking a fiber laser at a variable frequencies wherein a doped fiber segment contains two electro-optically tuned FBG's. The electro-optically tuned FBG may be fabricated by a thermal poling process.

Abstract: An improved highly doped waveguide is provided which comprises a waveguide having a dopant disposed therein, the dopant having a concentration of between 100 and 500,000 ppm, and wherein the concentration of the dopant enhances cross-relaxation between two elements of the dopant.

Abstract: The Hantavirinae encompass a large number of species which are distributed worldwide. Although hantaviruses generally reside in murine hosts, they are also the causative agents of a number of human diseases including hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). Tissue samples were obtained from hantavirus-infected rodents (e.g., Oligoryzomys microtis) and subjected to reverse transcription-polymerase chain reaction (RT-PCR) analysis to amplify hantaviral-specific nucleic acids. A molecular clone encoding the complete nucleocapsid (N) protein of the Rio Mamore Virus (RMV) was obtained and used to express high-levels of protein. The availability of the RMV N protein and its incorporation into immunodiagnostic assays will facilitate the detection of hantavirus-specific antibodies.