Abstract: A problem to be solved by the present invention is to provide a novel agent that promotes chemotaxis of corneal epithelial cells. The problem is solved by an agent that promotes chemotaxis of corneal epithelial cells, comprising PACAP, PACAP derivatives, or a pharmaceutically acceptable salt thereof, as an active ingredient. The agent that promotes chemotaxis of corneal epithelial cells of the present invention preferably comprise 1 or more peptides belonging to a group PACAP, PACAP derivatives, or a pharmaceutically acceptable salt thereof. Concentration of PACAP, PACAP derivatives, or a pharmaceutically acceptable salt thereof is particularly preferably 1×10?13 mol/L or more and 1×10?7 mol/L or less. An agent that promotes chemotaxis of corneal epithelial cells of the present invention may be widely used as pharmaceuticals and the like for the improvement of symptoms of eye diseases such as dry eyes.

Abstract: Disclosed herein are a recombination layer containing nanoparticles and an integrated tandem solar cell manufactured using the same. The integrated tandem solar cell includes a first solar cell having a form in which a rear electrode, a light absorption layer, and a buffer layer are stacked, a recombination layer formed on the buffer layer and including a triple layer structure which has first and second transparent conductive layers with a transparent conductive nanoparticle layer disposed therebetween, and a second solar cell disposed on and bonded to the recombination layer and including a perovskite layer.

Abstract: A pixel compensation circuit including a first transistor, a second transistor, a third transistor, a fourth transistor, a fifth transistor, a sixth transistor, a first capacitor, a second capacitor, and an organic light-emitting diode, each of the first transistor to the sixth transistor including a drain, a source and a gate.

Abstract: A ventilation detection method applied to a ventilation apparatus. The method may include monitoring respiratory parameters during mechanical ventilation of a patient by using a ventilation apparatus, the respiratory parameters at least comprising one of airway pressure and airway flow, and using changes in the respiratory parameters to identify whether man-machine counteraction or ventilation leakage has occurred.

Abstract: The present disclosure relates to a method for preparing a metal single-atom catalyst for a fuel cell. The method for preparing a metal single-atom catalyst uses a relatively lower amount of chemical substances as compared to the conventional methods and thus is eco-friendly, uses no liquid through the whole process and avoids a need for additional steps for separating and/or washing the catalyst after its synthesis, thereby allowing simplification of the process, and can produce a single-atom catalyst at low cost. In addition, unlike the conventional methods having a limitation in metallic materials, the method can be applied in common regardless of types of metals, and thus is significantly advantageous in that it can be applied widely to obtain various types of metal single-atom catalysts. Further, in the method for preparing a metal single-atom catalyst, metal atoms totally participate in the reaction. Thus, the method can minimize the usage of metal to provide high cost-efficiency.

Abstract: Methods and systems for identifying CNV membranes and vasculature in images obtained using noninvasive imaging techniques are described. An example method includes generating, by a first model based on at least one image of a retina of a subject, a membrane mask indicating a location of a CNV membrane in the retina. The method further includes generating, by a second model based on the membrane mask and the at least one image, a vasculature mask of the retina of the subject, the vasculature mask indicating CNV vascularization in the retina.

Abstract: In some aspects, a device comprises a substrate and at least one CMUT located on or in the substrate that provides ultrasound radiation to a brain of a patient. In some aspects, a method of guiding ultrasound radiation in the brain of a patient comprises receiving as a first input patient scan data, receiving as a second input information regarding configuration and/or properties of ultrasound transmitters adapted to transmit to the brain the ultrasound radiation, processing at least one of the first and second inputs and feeding the processed at least one of the first and second inputs into a physical acoustics model, and based on an output of the physical acoustics model and acquired data from the brain of the patient, generating an instruction to transmit to the brain of the patient the ultrasound radiation.

Abstract: Disclosed are a method and apparatus for managing a distraction to a smart device based on a context-aware rule.

Abstract: The present invention is directed to antigen binding proteins and in particular to IL-1? antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production.

Abstract: An elasticity measurement apparatus includes a lower layer structure having first and second openings, first and second deformable membranes covering the first and second openings to define first and second chamber and deformable by pressure within the first and second chambers respectively, a support layer structure on the lower layer structure to protrude and configured to support the first and second deformable membranes to be spaced apart from the elastic body, a driving portion to apply pressure within the first and second chambers to deform the first and second deformable membranes, and first and second deformation detecting portions to detect deformations of first and second deformable membranes. When the pressure within the first and second chambers is increased from a first pressure to a second pressure, the first deformable membrane is deformed with contacting the elastic body, while the second deformable membrane is deformed without contacting the elastic body.

Abstract: A transgenic non-human animal model for Neurofibromatosis type 1, wherein the Nf1 gene is specifically inactivated in BC cells and derivatives thereof. Also, an in vitro method of producing cutaneous and plexiform Neurofibromas (NFBs) and/or for studying the development and composition of plexiform NFBs, including culturing in vitro Prss56-expressing cells and-derivatives thereof obtained from the transgenic non-human animal model. Further, a method for screening a candidate compound for use as a drug to treat Neurofibromatosis type 1, cutaneous NFBs and/or plexiform NFBs including contacting the candidate compound Prss56-expressing cells and-derivatives thereof obtained from the transgenic non-human animal model or administering the candidate compound to the transgenic non-human animal model.

Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.

Abstract: The invention relates to the use of compounds of general structure (I) in modulation of the Wnt pathway wherein R1, R2, R3, R4 and R5 are each, independently, H or an alkyl group; D is selected from the group consisting of H, halogen, alkyl, cycloalkyl, aryl, and dialkylamino, each (other than H and halogen) being optionally substituted; Ar is an aryl or heteroaryl group, optionally substituted; Cy is an aryl, heteroaryl or a saturated ring containing at least one heteroatom, each being optionally substituted; and n is an integer from 1 to 3.

Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.

Abstract: In an organ of interest in a patient is emplaced a set of sensors designed to monitor parameters of the organ of interest, including at least nicotinamide adenine dinucleotide level and at least one parameter from among the group consisting of tissue blood flow, blood hemoglobin, and tissue reflectance. Substantially continuously, a vitality index of the organ of interest is computed based at least in part on the parameters monitored by the sensors at the organ of interest. Another point of the patient is monitored continuously for a systemic reference, NADH level and at least two parameters from among the group consisting of blood flow (BFS), blood hemoglobin, and tissue reflectance. Substantially continuously, a systemic vitality index is computed from the measured systemic parameters. The vitality index of the organ of interest and systemic vitality index are monitored for a divergence in the temporal trend.

Abstract: A low birefringence ferroelectric liquid crystal (FLC) mixture composed of at least two components shows birefringence in the range 0.05 to 0.14, which is suitable for the modern display and photonic devices. The cell gap can be tuned from 1.5 ?m to 4 ?m to reduces the fabrication complexity and chromatic distortion by electro-optical modulation. The FLC mixtures can be employed in a wide temperature range. The characteristics of the said FLC mixture can be tuned by tuning the concentration of the constituents of the mixture. The helical pitch of the FLC mixtures can be varied from 100 nm to 10 ?m. A smectic tilt angle can be varied between 17° to 45° and the spontaneous polarization can be tuned over a wide range to meet requirements of different electro-optical modes, and the FLC mixture is applicable for a wide variety of electro-optical effects.

Abstract: An extraction system for obtaining oils and other constituents from raw botanical materials includes an array of separation chambers for fractionalized recovery of dissolved constituents in a supercritical solvent fluid. Collection of the dissolved constituents is facilitated with a pressure-stable collection vessel that is adaptable to sequentially collect precipitate from the array of separation chambers.

Abstract: A waste gas purification system according to an embodiment includes an adsorption-catalysis-oxidation unit, an enhanced absorption unit, an air inducing unit, and a flue gas discharge and heat exchange unit that are sequentially connected. The waste gas enters a heat exchange device of the flue gas discharge and heat exchange unit through a first waste gas delivery pipeline to perform heat exchange, then is converged with waste gas in a second waste gas delivery pipeline and enters a third waste gas delivery pipeline. Waste gas in the third waste gas delivery pipeline is purified after sequentially passing through the adsorption-catalysis-oxidation unit and the enhanced absorption unit. Purified flue gas is introduced into the flue gas discharge and heat exchange unit by the air inducing unit, and the purified flue gas is discharged after performing heat exchange with the heat exchange device.

Abstract: Microfluidic cartridges or devices for serum separation and blood cross-match analysis are provided. The devices may include a serum separation subcircuit alone or in combination with a solute mixing subcircuit. The serum separation subcircuit promotes on-cartridge clotting of a blood sample and manipulates the flow of the separated serum sample for subsequent cross-match analysis with a second blood sample, for example. The solute mixing subcircuit includes at least two intake channels, one for a whole blood sample from, for example, a blood donor and the other for the separated serum sample from, for example, a transfusion recipient. The solute mixing subcircuit further includes a serpentine mixing channel conjoined to a downstream channel. Under vacuum generated by a conjoined finger pump, the two input streams fill the serpentine mixing and downstream channels due to capillary action, enabling visualization of an agglutination reaction.