Abstract: The present disclosure relates to devices and methods for accessing a targeted vessel, such as a coronary artery, near the aortic root. A catheter device includes a proximal section, an intermediate section, and a distal section. The intermediate section includes a more proximal section (a proximal-intermediate section) and a more distal section (a distal-intermediate section). The proximal-intermediate section is microfabricated to enable preferred bending along a single plane. The distal-intermediate section is more rigid than the proximal-intermediate section and the distal section. In use, the proximal-intermediate section abuts against the aortic wall and bends to allow the distal-intermediate section to extend across the aortic root toward a targeted vessel on the opposite side of the aorta.

Abstract: The present disclosure relates to guidewire devices having shapeable tips and effective torquability. A guidewire device includes a core having a proximal section and a tapered distal section. A tube structure is coupled to the core such that the tapered distal section extends into the tube structure. The tube structure includes a plurality of bypass cuts formed tangentially within the tube structure to increase the flexibility of the tube structure and to reduce the tendency of resilient forces from the tube structure to disrupt a shaped distal tip of the guidewire device.

Abstract: The present disclosure relates to guidewire devices having shapeable tips and effective torquability. A guidewire device includes a core having a proximal section and a tapered distal section. A tube structure is coupled to the core such that the tapered distal section extends into the tube structure. The tube structure includes a plurality of bypass cuts formed tangentially within the tube structure to increase the flexibility of the tube structure and to reduce the tendency of resilient forces from the tube structure to disrupt a shaped distal tip of the guidewire device.

Abstract: This disclosure describes a micro-cutting machine for forming cuts in catheters, guidewires, and similar products. The micro-cutting machine can directly control the dimensions of the resultant beams being cut into these types of products, and can also capture images of each cut for feedback control and accuracy verification. The micro-cutting machine has two cutting blades each with cutting edges aligned with a vertical axis. Motors operate to move the cutting blades in a direction perpendicular to the longitudinal axis of the stock material being cut to form a pair of opposing grooves in the stock material with each cut.

Abstract: The present disclosure relates to guidewire devices having shapeable tips and effective torquability. A guidewire device includes a core having a proximal section and a tapered distal section. A tube structure is coupled to the core such that the tapered distal section of the core extends into and distally beyond the tube structure. The portion of the core extending distally beyond the tube forms a shapeable tip. A polymer covering encompasses the tip. The tip is configured to reduce the tendency of resilient forces from the tube structure to disrupt a customized shape of the tip.

Abstract: The present disclosure relates to guidewire devices having shapeable tips and effective torquability. A guidewire device includes a core having a proximal section and a tapered distal section. A tube structure is coupled to the core such that the tapered distal section of the core extends into and distally beyond the tube structure. The portion of the core extending distally beyond the tube forms a shapeable tip. One or more coils also extend distally beyond the tube. The tip is configured to reduce the tendency of resilient forces from the tube structure to disrupt a customized shape of the tip.

Abstract: The present disclosure relates to vascular devices such as guidewires and microcatheters having integrated coil sections for optimizing torquability, flexibility, and ability to shape and maintain the distal tip. A guidewire device includes a core and a tube structure coupled to the core such that at least a portion of the core passes into the tube structure. A distal section of the tube structure includes a spiral cut arrangement that configures the distal section as an integral coil integrally incorporated as part of the tube structure. The integrated coil configuration increases the flexibility of the tube structure to reduce the tendency of resilient forces from the tube structure to disrupt a shaped distal tip of the guidewire device.

Abstract: A guidewire device comprising an elongated outer member having an outer surface and an interior surface forming a lumen extending from a proximal end to a distal end, wherein an outer diameter of said distal end is larger than an outer diameter of said proximal end; and an inner member disposed within a portion of said lumen, and embodiments thereof.

Abstract: This disclosure describes a micro-cutting machine for forming cuts in catheters, guidewires, and similar products. The micro-cutting machine can directly control the dimensions of the resultant beams being cut into these types of products, and can also capture images of each cut for feedback control and accuracy verification. The micro-cutting machine has two cutting blades each with cutting edges aligned with a vertical axis. Motors operate to move the cutting blades in a direction perpendicular to the longitudinal axis of the stock material being cut to form a pair of opposing grooves in the stock material with each cut.

Abstract: A guidewire device comprising: a micro-fabricated elongated outer member having an outer surface and an interior surface forming a lumen extending from a proximal end to a distal end, wherein said outer member is formed from two or more stock materials; and an inner member disposed within a portion of said lumen, and embodiments thereof.

Abstract: An embodiment is directed to an embolic device comprised of a coil made of a first material and disposed on the inside of a tube structure made of a second material. The tube structure has micro-fabricated fenestrations formed in the tube to provide fluid communication between the lumen of the tube and the surrounding environment, thereby exposing the inner coil. The fenestrations also trip flow around the embolic device. In one embodiment, the embolic device is comprised of a tantalum coil on the inside of a polyetheretherketone (PEEK) tube. The PEEK tube has the advantage of providing a micro-machined delivery implant frame and radiopacity, while the internal tantalum coil provides radiopacity and thrombogenicity. A material other than PEEK may be used for embodiments of embolic devices without departing from the spirit of the disclosure.

Abstract: Micro-cutting machines for forming cuts in catheters, guidewires, and similar products, are disclosed, including a micro-cutting machine that can directly control the dimensions of the resultant beams being cut into products, and that can capture images of each cut for feedback control and accuracy verification.

Abstract: A catheter device comprising an elongated outer member having an outer surface and an interior surface forming a lumen extending from a proximal end to a distal end, wherein an outer diameter of said distal end is larger than an outer diameter of said proximal end, and embodiments thereof.

Abstract: A guidewire device comprising: a micro-fabricated elongated outer member having an outer surface and an interior surface forming a lumen extending from a proximal end to a distal end; an outer elastomer laminate layer in contact with at least a portion of said outer surface; and an inner member disposed within a substantial portion of said lumen, and embodiments thereof.

Abstract: A guidewire device comprising a micro-fabricated elongated outer member having an outer surface and an interior surface forming a lumen extending from a proximal end to a distal end and a plurality of fenestrations made through said outer surface and said interior surface into a least a portion of said lumen; an outer elastomer laminate layer in contact with at least a portion of said outer surface and filling at least a portion of said plurality of fenestrations; and an inner member disposed within a substantial portion of said lumen, and embodiments thereof.

Abstract: A catheter device is disclosed including an elongated outer member having a plurality of resultant beams of substantially identical thickness along a length of the outer member, where each resultant beam from among the plurality of resultant beams is formed between two simultaneously cut fenestrations on substantially opposite sides of the outer member, the outer member having an outer surface and an interior surface forming a lumen extending from a proximal end to a distal end, where the outer member is formed from two or more different stock materials.

Abstract: A guidewire device comprising: a micro-fabricated elongated outer member having an outer surface and an interior surface forming a lumen extending from a proximal end to a distal end; an outer elastomer laminate layer in contact with at least a portion of said outer surface; and an inner member disposed within a substantial portion of said lumen, and embodiments thereof.

Abstract: A catheter device comprising: a micro-fabricated elongated outer member having an outer surface and an interior surface forming a lumen extending from a proximal end to a distal end and a plurality of fenestrations made through said outer surface and said interior surface into at least a portion of said lumen; and an outer elastomer laminate layer in contact with at least a portion of said outer surface and filling said plurality of fenestrations, and embodiments thereof.

Abstract: A guidewire device comprising a micro-fabricated elongated outer member having an outer surface and an interior surface forming a lumen extending from a proximal end to a distal end and a plurality of fenestrations made through said outer surface and said interior surface into a least a portion of said lumen; an outer elastomer laminate layer in contact with at least a portion of said outer surface and filling at least a portion of said plurality of fenestrations; and an inner member disposed within a substantial portion of said lumen, and embodiments thereof.

Abstract: A guidewire device comprising: a micro-fabricated elongated outer member having an outer surface and an interior surface forming a lumen extending from a proximal end to a distal end, wherein said outer member is formed from two or more stock materials; and an inner member disposed within a portion of said lumen, and embodiments thereof.