Abstract: A breast compression device suitable for compressing a breast for an x-ray guided biopsy, the device comprising: a) a base for contacting a portion of the surface of the breast; b) a flexible band, anchored to the base, adapted to be positioned on a side of the breast opposite the base, when the breast is inserted between the base and the band, which band is adapted to be wrapped at least part way around the breast; and c) a tensioning device, adapted to tension the flexible band around the inserted breast when the flexible band is anchored to the base, thereby compressing the breast between the flexible band and the base.