Patents Assigned to Scientific Pharmaceuticals
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Patent number: 9301905Abstract: Disclosed herein are dental temporary filling material and cement formulations comprising a hydrophobic matrix of a hydrophobic material in which an inorganic hardening material and fine, hydrophilic, water-insoluble solid particles are dispersed. The hydrophilic particles serve to conduct water into the hydrophobic matrix to increase the depth and degree of cure in the oral environment as compared to a similar or substantially identical formulation lacking said hydrophilic component.Type: GrantFiled: August 11, 2010Date of Patent: April 5, 2016Assignee: Scientific Pharmaceuticals, Inc.Inventors: David V. Butler, Karla S. Somerville, Jan A. Orlowski
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Patent number: 9028254Abstract: Disclosed herein are acrylic and methacrylic acid ester-based polymeric materials containing as flexibilizing and brittleness reducing agents 1-60% of C4-C8 polyalkylene or polyalkyldiene compounds, preferably having a molecular weight of 300-2100, and the use of such materials in dentistry and medicine.Type: GrantFiled: July 12, 2013Date of Patent: May 12, 2015Assignee: Scientific Pharmaceuticals, Inc.Inventors: Jan A Orlowski, David V Butler, Alice Chin
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Publication number: 20120040310Abstract: Disclosed herein are dental temporary filling material and cement formulations comprising a hydrophobic matrix of a hydrophobic material in which an inorganic hardening material and fine, hydrophilic, water-insoluble solid particles are dispersed. The hydrophilic particles serve to conduct water into the hydrophobic matrix to increase the depth and degree of cure in the oral environment as compared to a similar or substantially identical formulation lacking said hydrophilic component.Type: ApplicationFiled: August 11, 2010Publication date: February 16, 2012Applicant: SCIENTIFIC PHARMACEUTICALS, INC.Inventors: David V. Butler, Karla S. Somerville, Jan A. Orlowski
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Publication number: 20090239969Abstract: Disclosed herein are acrylic and methacrylic acid ester-based polymeric materials containing as flexibilizing and brittleness reducing agents 1-60% of C4-C8 polyalkylene or polyalkyldiene compounds, preferably having a molecular weight of 300-2100, and the use of such materials in dentistry and medicine.Type: ApplicationFiled: June 2, 2009Publication date: September 24, 2009Applicant: SCIENTIFIC PHARMACEUTICALS, INCInventors: Jan A. Orlowski, David V. Butler, Alice Chin
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Patent number: 7563833Abstract: Disclosed are dental varnishes comprising reaction products of rosins with polyalcohols dissolved in mixtures of C2-C4 alcohols with C5-C7 hydrocarbons or C5-C7 hydrocarbons alone which have been found effective in preventing tooth decay and alleviating tooth sensitivity. Such varnishes may, optionally, incorporate therapeutic, antimicrobial and sensory enhancing ingredients.Type: GrantFiled: November 17, 2006Date of Patent: July 21, 2009Assignee: Scientific Pharmaceuticals, Inc.Inventors: Jan A. Orlowski, David V. Butler
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Patent number: 7335691Abstract: Disclosed are dental varnishes comprising reaction products of rosins with polyalcohols dissolved in mixtures of C2-C4 alcohols with C5-C7 hydrocarbons which have been found effective in preventing tooth decay and alleviating tooth sensitivity. Such varnishes may, optionally, incorporate therapeutic, antimicrobial and sensory enhancing ingredients.Type: GrantFiled: July 2, 2004Date of Patent: February 26, 2008Assignees: Scientific Pharmaceuticals, Inc., Omnii Oral PharmaceuticalsInventors: Jan A. Orlowski, David V. Butler, Lindsay K. McKinley
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Patent number: 7067115Abstract: Disclosed is a process and composition for bleaching teeth made up of two components blended together before each application. The method and composition offers faster results while significantly reducing the possibility of user discomfort. One of said components comprises carbamide peroxide, the other contains salts and hydroxides and/or oxides of metals belonging to the first or second group of the Periodic Table which stimulate the generation of radical oxygen. In one embodiment, the first part comprises up to 50% water by weight and optionally comprises a stabilizer. In some embodiments, the first component is substantially colorless and the second component comprises a dye indicator which discolors or loses color when exposed to radical oxygen generated by the mixing of the two components.Type: GrantFiled: April 17, 2002Date of Patent: June 27, 2006Assignee: Scientific Pharmaceuticals, Inc.Inventors: Jan A. Orlowski, David V. Butler
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Patent number: 6981875Abstract: Securing a dental post or a crown or bridge onto the dentin portion of a prepared tooth by utilizing a no-mix, two component, self-curing cement wherein the first component of the cement is applied to the interior dentin surfaces of a post hole, or onto the dentin surface of the tooth receiving the crown or bridge, and applying the second component of the cement onto the surface of a post, or crown or bridge so that when the post or crown or bridge is fitted onto the exposed dentin of a prepared tooth, the complementary components of the cement immediately chemically set to firmly secure the post, crown or bridge onto the prepared tooth. The respective components of the no-mix, two component, self-curing cement formulation for practicing the method require that each include a methacrylate resin. One of the components also includes an aromatic tertiary amine and the other component includes an organic peroxide.Type: GrantFiled: June 28, 2002Date of Patent: January 3, 2006Assignees: Centrix, Inc., Scientific Pharmaceuticals, Inc.Inventors: Jan A. Orlowski, John J. Discko, Jr.
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Patent number: 6696043Abstract: Described herein is a novel teeth whitening chewing gum formulation comprising bivalent metal peroxide(s) and anhydrous organic acids. Upon mastication in the oral environment, the acids react with the peroxide to form hydrogen peroxide in situ, in an environment stimulating the decomposition of such peroxide to form water and radical oxygen. The system is characterized by its efficacy and convenience. The teeth whitening composition of the preferred embodiment is also virtually insensitive to storage conditions, allowing for an extended shelf life.Type: GrantFiled: August 16, 2001Date of Patent: February 24, 2004Assignee: Scientific Pharmaceuticals, Inc.Inventors: Jan A. Orlowski, David V. Butler, Amy P. Noss, Mahin Mapar
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Patent number: 6488913Abstract: Described herein is a novel high efficiency teeth bleaching system based on thesynergetic action of the combination of hydrogen peroxide (in a free form or in the form of its adduct with urea) and peroxide and/or percarbonates of metals belonging to the first or second group of the periodic table. In one embodiment, the system of the preferred embodiment comprises two components, one containing hydrogen peroxide or carbamide peroxide (hydrogen peroxide/urea adduct), and the other containing metal peroxides and/or percarbonates. Mixing of the two components results in the accelerated generation of radical oxygen, which relates to faster teeth bleaching action.Type: GrantFiled: August 16, 2001Date of Patent: December 3, 2002Assignee: Scientific Pharmaceuticals, INCInventors: Jan A. Orlowski, David V. Butler
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Patent number: 6447757Abstract: Disclosed are compositions for bleaching teeth comprising at least two parts blended together before each application. The compositions offer extended shelf life and accelerated bleaching action while significantly reducing the possibility of user discomfort. In preferred embodiments, one part of the composition comprises peroxides of monovalent or bivalent metals such as sodium, potassium, magnesium, calcium, strontium, and zinc, and another part comprises an aqueous solution of one or more acids able to convert said metal peroxides into hydrogen peroxide, such reaction occurring under conditions resulting in the acceleration of the generation of radical oxygen and, consequently, the teeth whitening process. The inventive compositions allow for adequate water in the composition to avoid tissue desiccation and associated user discomfort without compromising the shelf life of the composition.Type: GrantFiled: November 8, 2000Date of Patent: September 10, 2002Assignee: Scientific Pharmaceuticals, Inc.Inventors: Jan A. Orlowski, David V. Butler, Amy P. Noss
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Patent number: 6365134Abstract: A process and composition for bleaching teeth made up of two formulations blended together before each application. The invention offers faster results while significantly reducing the possibility of user discomfort. One of said formulations contains hydrogen peroxide (in a free form or in the form of an adduct), the other contains salts and hydroxides and/or oxides of metals belonging to the first or second group of the Periodic Table which stimulate the generation of radical oxygen. The invention allows for balancing pH and assuring adequate water concentration to avoid tissue desiccation and user discomfort without compromising shelf life of the device.Type: GrantFiled: July 17, 2000Date of Patent: April 2, 2002Assignee: Scientific Pharmaceuticals, Inc.Inventors: Jan A. Orlowski, David V. Butler
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Patent number: 6284030Abstract: A one-component paste-consistency dental material which cures upon contact with oral fluids intended primarily for use as a temporary restorative/cement. The formulation includes solid particles reactive with water dispersed in a hydrophobic viscous binder which, upon exposure to moisture, will solidify to a depth in excess of 8 mm measured from the surface/water contact area. The curing mechanism relies on both formation of hydrates and reaction of organic polyacids with alkaline glass or metal oxides, or the salts of metal oxides with weak acids. The resulting cured material is non toxic, resistant to deterioration in oral fluids, possesses adequate water resistance, and, optionally, may release fluoride desirable for prevention of secondary decays and alleviation of postoperative tooth sensitivity.Type: GrantFiled: September 29, 1999Date of Patent: September 4, 2001Assignee: Scientific Pharmaceuticals, IncInventors: Jan A. Orlowski, David V. Butler
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Patent number: 5965632Abstract: A two paste glass ionomer type dental cement system, with both pastes being, preferably, of similar consistency. The first paste represents primarily a suspension of an inert filler in a water solution of polyacrylic acid, or its copolymers with other ethylenically unsaturated acids, having molecular weight of 25,000 to 100,000 and, optionally, various additives, such as filler suspending agents, coloring agents, agents influencing working/setting time (retardants or accelerators), Theological agents, pH modifiers, etc. The other paste represents primarily a particulate glass flux containing silicon and aluminum oxides, calcium fluoride and, optionally, other inorganic salts, including aluminum phosphate, and sodium, barium and aluminum fluorides, suspended in a liquid medium consisting primarily of a water solution of a hydrophilic acrylic monomer or polymer. In order to achieve a desirable consistency, organic or inorganic thickening agents may be added in suitable quantities.Type: GrantFiled: June 20, 1997Date of Patent: October 12, 1999Assignee: Scientific Pharmaceuticals Inc.Inventors: Jan A. Orlowski, David V. Butler, Jeffrey R. H. MacDonald
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Patent number: 5925689Abstract: Adhesive coatings designed primarily for protecting, restoring, repairing, or modifying surfaces of, objects made of polymeric materials. Such coatings are particularly useful in application over worn, cracked, discolored, or otherwise defective objects made of polyacrylic, polystyrene, and polycarbonate resins. The adhesives of this invention are basically comprised of blends containing a substantial concentration of tetrahydrofurfuryl methacrylate and/or furfuryl methacrylate.Type: GrantFiled: June 20, 1997Date of Patent: July 20, 1999Assignee: Scientific Pharmaceuticals, Inc.Inventors: Jan A. Orlowski, David V. Butler, Jeffrey R. H. MacDonald
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Patent number: 5141436Abstract: A method of bonding polymeric articles to tooth structures employing a light curable primer, including etching the surface of said tooth, applying a primer to the polymeric article the primer including light curable acrylate or methacrylate monomers and a volatile solvent which softens or partially dissolves the polymeric material of the article, applying light curable adhesive to the article or tooth, and applying the article to the tooth and curing the primer and the adhesive by applying light.Type: GrantFiled: November 13, 1989Date of Patent: August 25, 1992Assignee: Scientific Pharmaceuticals, Inc.Inventors: Jan A. Orlowski, David V. Butler
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Patent number: 4648845Abstract: There is provided a method for indirect bonding of chemically or light curable resin based restoratives especially acrylates and methacrylates, to the metal base of dental cast restorations. The invention is particularly useful in cases of in situ repairs of damaged or worn porcelain or polymeric veneers on cast restorations made of precious and non-precious metals. According to the invention, the exposed metal of the restoration is covered with a layer of primer consisting essentially of a copolymer of polymethacrylic or polyacrylic acid followed by the application of the polymerizable restorative material.Type: GrantFiled: November 27, 1985Date of Patent: March 10, 1987Assignee: Scientific Pharmaceuticals, Inc.Inventors: Jan A. Orlowski, David V. Butler
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Patent number: 4495172Abstract: A composition, method and product are provided for the coating of human nails. The coating composition comprises a curable ethoxyethylmethacrylate monomer, a polyethylmethacrylate homopolymer or copolymer filler and a cross-linking agent. The method involves applying the coating composition upon nails and curing the composition. The product involves a separately packaged liquid and powder, wherein the liquid comprises ethoxyethylmethacrylate monomer and a cross-linking agent and the powder comprises a polyethylmethacrylate filler.Type: GrantFiled: February 4, 1980Date of Patent: January 22, 1985Assignee: Scientific Pharmaceuticals, Inc.Inventors: Jan A. Orlowski, David V. Butler, Patrick D. Kidd
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Patent number: 4490115Abstract: Dental materials containing dimethacrylates having the following chemical structures: ##STR1## where R.sub.1 and R.sub.2 may be the same or different and are cyclohexyl or phenyl groups which may be substituted or unsubstituted; andR.sub.3 is an aliphatic cycloaliphatic or aromatic group having 6 to 15 carbon atoms.Type: GrantFiled: April 18, 1983Date of Patent: December 25, 1984Assignee: Scientific Pharmaceutical, Inc.Inventors: Jan A. Orlowski, David V. Butler, Patrick D. Kidd
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Patent number: 4479782Abstract: There is provided a method of bonding orthondontic brackets to teeth with an adhesive comprised of a mixture of an aromatic or hydroaromatic and aliphatic methacrylate or acrylate, an alpha, .beta.-diketone and a tertiary amine and, optionally, organic or inorganic fillers, polymerization stabilizers and other additives, such adhesive being cured by a light source having white-light output of no less than 25,000 foot candles. The light is applied to the occlusal surface of the tooth or the side opposite to the side on which the bracket is placed. Thus the adhesive is irradiated indirectly.Type: GrantFiled: April 18, 1983Date of Patent: October 30, 1984Assignee: Scientific Pharmaceuticals, Inc.Inventors: Jan A. Orlowski, David V. Butler