Abstract: The present invention concerns a method for generating a pattern of light, this method comprising the following steps: a) emitting an input laser pulse (P1), b) deflecting the input laser pulse (P1) by a first deflector (22) to obtain a first laser pulse, c) deflecting the first laser pulse (P3) by a second deflector (24) to obtain a second laser pulse (P4), and d) focusing the pulse (P4) by an optical element characterized in that: —the first deflector (22) shapes the first laser pulse (P3) according to a first function, —the second deflector (24) shapes the second laser pulse (P4) according to a second function, and—the first function f(x) and the second function g(y) are computed and/or optimized to obtain the desired pattern of light.

Abstract: The invention relates to a device for forming laser pulses comprising: an input for a pulsed laser beam; a spatial phase modulator (300), arranged on the trajectory of said pulsed laser beam so as to be illuminated thereby; a control means designed to configure said spatial phase modulator so as to emulate a diffraction grating (3, 3?) having a diffraction efficiency that varies along one spatial direction (s) identified by the intersection of the modulator surface with the diffraction plane (xz); and spatial filtering means (5) for a light beam diffracted by said grating; whereby a laser pulse (P1) at the device input is converted to a train of elementary output pulses (PS) having temporal intensity and/or phase and/or polarization modulation. The invention further relates to a laser pulse forming process based on the use of such a device.

Abstract: The present invention relates to a process for grafting polymers onto a metallic material, comprising the following steps: a) oxidation of the surface of the metallic material, resulting in an oxidized metallic material; b) grafting of a polymer at the surface of said oxidized metallic material by radical polymerization of a monomer, said radical polymerization comprising an initiation step and a propagation step, said initiation step being carried out by UV irradiation with a UV source diffusing a power at the surface of the material of greater than 72 mW·cm?2, said UV irradiation being carried out for a duration greater than 15 minutes and less than 180 minutes, said process resulting in a grafted metallic material. The present invention also relates to the materials capable of being obtained by this process, and applications of the latter, in particular as articular or dental implants.

Abstract: A method for characterizing terahertz radiation using spectral domain interferometry, comprising overlapping a pump beam and a terahertz beam in a detecting crystal; obtaining two probe pulses by propagating the probe beam into a polarization maintaining single-mode optical fiber after the detecting crystal; and measuring a change in the optical path difference between the two probe pulses. The system comprises a detection crystal, where a terahertz pulse and a probe beam are made to overlap; a polarization-maintaining optical fiber propagating the probe beam after the detection crystal and outputting two probe pulses; and a spectrometer where the two probe pulses interfere.

Abstract: A metallacrown complex has the formula: Ln(III)[12-MC-4]2[24-MC-8], wherein MC is a metallacrown macrocycle with a repeating sub-unit consisting of a transition metal (M(II)) and a hydroxamic acid (HA) ligand that produces a ligand-based charge transfer state when incorporated into the metallacrown complex. In an example of a method for making the metallacrown complex, a hydroxamic acid (HA) ligand that is to produce a ligand-based charge transfer state when incorporated into the metallacrown complex, a transition metal salt, and a rare-earth salt are dissolved in a solvent to form a solution. A base is added to the solution. The solution is stirred at a predetermined temperature for a predetermined time. The solution is exposed to a purification method to produce crystals of the metallacrown complex.

Abstract: Method for measuring a physical parameter in soft tissues of a mammal, in which a mechanical shear wave is propagated through the soft tissues and observation of the propagation leads to determine values of a shear wave propagation parameter. The physical parameter is computed on the basis of these values.

Abstract: The invention concerns a gallinacean embryo in which cancer cells have been grafted within the embryo tissue, characterised in that the embryo is at a developmental stage between the HH10 and HH25 stages at the time of the grafting, wherein said cancer cells are not neuroblastoma cells and said cells form tumors inside the embryo.

Abstract: The present invention relates to a vector comprising a nucleic acid sequence that encodes the APP protein and/or the PS1 protein or variants thereof. The invention also relates to a method for inducing the Alzheimer's disease in an animal using the vector of the invention and to animal model having the Alzheimer's disease obtained by said method.

Abstract: A method for producing a thermal barrier in a multilayered system for protecting a metal part made of superalloy, by producing a thermal treatment by flash sintering protection materials in layers superposed on the metal part in an SPS machine enclosure. The layers contain, on a superalloy substrate, at least two layers of zirconium-based refractory ceramics. A metal part is produced according to a SPS flash sintering method and contains a superalloy substrate, a metal sub-layer, a TGO oxide layer and the thermal barrier formed by the method. A first ceramic is an inner ceramic designed to have a substantially higher expansion coefficient. An outer ceramic is designed to have at least lower thermal conductivity, and at least one of a sintering temperature or maximum operating temperature that is substantially higher. The thermal barrier has a composition and porosity gradient from the metal sub-layer to the outer ceramic.

Abstract: The invention relates to a method for manufacturing mirrors with saturable semiconducting absorptive material, which includes: depositing a saturable semiconducting absorptive material (205) onto a growth substrate (200) in order to form a structure; depositing at least one metal layer onto the structure such as to form a first mirror (211); and depositing a heat-conductive substrate (212) onto the metal layer by electrodeposition through an electrically insulating mask (312), allowing the selective deposition of the thermally conductive substrate, in order to predefine the perimeter of the mirrors with saturable semiconducting absorptive material.

Abstract: The invention proposes a device for analyzing nucleic acid molecules (M), comprising: —a bead (20), on which one molecule can be anchored at one end, —a surface (520), on which the molecule can be anchored at the other end, —an actuator (30), adapted to cause the bead to move relative to said surface in one direction, —a sensor (50), adapted to measure a distance between the bead and the surface, the device further comprising a well (11), having an axis (X-X) extending along the direction of motion of the bead and a bottom (110) formed by said surface, said well being filled with electrically conductive solution (40), and receiving the bead, the sensor being adapted to measure an impedance of the well, depending on a distance between the bead and the surface, to determine, the distance between the bead and the surface.

Abstract: The present invention generally relates to an immunogenic construct,useful for redirecting an EBV-existing immune response towards an undesired target cell and/or microorganism, to methods for preparing said conjugate, to a pharmaceutical applications comprising said conjugate, and to medical applications thereof.

Abstract: The invention relates to a Rac1 inhibitor for use as bronchodilator in a patient in need thereof. The invention provides a Rac1 inhibitor for use in a method for inducing bronchodilation in a patient in need thereof. The invention also relates to a Rac1 inhibitor for use in a method for reducing AHR in a patient in need thereof.

Abstract: The invention relates to a method for manufacturing an electronic device, particularly a device including a flexible and/or low-cost substrate and/or carbon nanotubes, and also relates to electronic devices produced using said method.

Abstract: The present invention relates to chemically defined culture medium comprising at least one osmoprotectant compound and at least one fatty acid for the detection of a broad range of microorganisms.

Abstract: The present invention relates to a nanofilm including at least one polycation and one polysulfated oligosaccharide. The present invention also relates to the nanofilms obtainable by simultaneously or alternately sputtering at least one polycation solution and at least one polysulfated oligosaccharide solution and to the use of said nanofilms on skin, skin conditions, wounds, or mucous membranes. The present invention also relates to a nanofilm for the use thereof in a method for releasing polysulfated oligosaccharide upon contact with exuding wounds.

Abstract: The invention relates to a method for controlling an automated orbital sander, in which method an electrically powered orbital sander is moved around automatically, at constant pressure, over the surface of an object, along at least one predefined sanding path so as to perform sanding, characterized in that the instantaneous power consumed by the sander along the sanding path is measured and in that the measurement thus taken is processed in order to deduce therefrom information regarding the level of abrasion along said path and/or to detect any sanding incident that has occurred along the latter.

Abstract: The present invention relates to a method for determining whether a candidate human transplant donor is at risk of inducing acute graft versus host disease (aGVHD) in a human transplant recipient, which may in turn allow the selection of a donor exhibiting no risk for the recipient. The present invention also relates to a method for adjusting the immunosuppressive treatment administered to a human transplanted recipient following its graft transplantation after having performing the method for determining risk of the invention. The methods comprise expanding the candidate donor's iNKT cells (invariant NKT cells) and determining the presence or absence of expansion of the CD4(?) iNKT cell sub-population. In particular, CD3+CD4? TCRV[alpha]24V[beta]11 cells are determined. Kits are disclosed.

Abstract: Techniques are described for chemical sequestration of carbon dioxide and production of precipitated magnesium carbonate. The process can include contacting carbon dioxide from industrial emissions with water and magnesium-containing particulate material, such as serpentinite, which is thermally pre-treated and has a particle size of at most 75 microns. The process can also include separation of the loaded aqueous stream from the solids, followed by precipitation of magnesium carbonate material that includes carbon and oxygen from industrial emissions and magnesium from serpentinite or chrysotile mining residue, for example.

Abstract: An asynchronous circuit including an asynchronous pipeline including two or more stages, each stage having: a buffering circuit for temporarily storing data to be transferred from one stage to the next based on a handshake protocol, the buffering circuit including a non-volatile memory; and a data presence detection circuit adapted to generate a data presence detection value indicating whether or not data is stored by the buffering circuit; and a control circuit adapted to perform a data back-up operation by independently controlling each buffering circuit to back-up the data it stores to its non-volatile memory based on the corresponding data presence detection value.