Patents Assigned to SciFluor Life Sciences, Inc.
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Patent number: 10752625Abstract: The present application relates to methods of preparing a compound of formula I: or a pharmaceutically acceptable salt or solvate thereof.Type: GrantFiled: February 28, 2019Date of Patent: August 25, 2020Assignee: SciFluor Life Sciences, Inc.Inventor: Takeru Furuya
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Patent number: 10676437Abstract: The application relates to 4-(substituted amino)phenyl carbamate derivatives, or pharmaceutically acceptable salts or solvates thereof, as KCNQ2/3 potassium channel modulators, and methods of their uses.Type: GrantFiled: December 13, 2018Date of Patent: June 9, 2020Assignee: SciFluor Life Sciences, Inc.Inventors: Takeru Furuya, Ben C. Askew, D. Scott Edwards
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Patent number: 10308647Abstract: The present application relates to compounds and methods for the modulation (e.g., inhibition) of the enzyme indoleamine 2,3-dioxygenase and/or tryptophan 2,3-dioxygenase (IDO/TDO), and methods of treating diseases and disorders in which IDO/TDO plays a role.Type: GrantFiled: October 28, 2016Date of Patent: June 4, 2019Assignee: SciFluor Life Sciences, Inc.Inventors: Ben C. Askew, Takeru Furuya
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Patent number: 10301307Abstract: The present invention relates to fluorinated compounds of formula I and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing the fluorinated compounds of the invention, and methods of treating fibrosis, macular degeneration, diabetic retinopathy (DR), macular edema, diabetic macular edema (DME), and macular edema following retinal vein occlusion (RVO), by administering these compounds and pharmaceutical compositions to subjects in need thereof.Type: GrantFiled: September 11, 2017Date of Patent: May 28, 2019Assignee: SciFluor Life Sciences, Inc.Inventors: Ben C. Askew, Takeru Furuya
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Patent number: 10253025Abstract: The present application relates to methods of preparing a compound of formula I: or a pharmaceutically acceptable salt or solvate thereof.Type: GrantFiled: March 30, 2018Date of Patent: April 9, 2019Assignee: SciFluor Life Sciences, Inc.Inventor: Takeru Furuya
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Patent number: 10155758Abstract: The invention relates to fluorinated compounds and their use as integrin receptor antagonists. Novel fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives and pharmaceutically acceptable salts or solvates thereof and their use are described.Type: GrantFiled: September 26, 2017Date of Patent: December 18, 2018Assignee: SciFluor Life Sciences, Inc.Inventors: Ben C. Askew, Richard W. Heidebrecht, Takeru Furuya, Mark E. Duggan
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Patent number: 10118929Abstract: The present disclosure relates to fluorinated compounds of formula I and methods of synthesizing these compounds. The present disclosure also relates to pharmaceutical compositions containing the fluorinated compounds of the disclosure, and methods of treating fibrosis, macular degeneration, diabetic retinopathy (DR), macular edema, diabetic macular edema (DME), and macular edema following retinal vein occlusion (RVO), by administering these compounds and pharmaceutical compositions to subjects in need thereof.Type: GrantFiled: April 27, 2017Date of Patent: November 6, 2018Assignee: SciFluor Life Sciences, Inc.Inventors: Takeru Furuya, Ben C. Askew
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Patent number: 10106537Abstract: The present invention relates to fluorinated compounds of formula I and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing the fluorinated compounds of the invention, and methods of treating macular degeneration, diabetic retinopathy (DR), macular edema, diabetic macular edema (DME), and macular edema following retinal vein occlusion (RVO), by administering these compounds and pharmaceutical compositions to subjects in need thereof.Type: GrantFiled: June 27, 2017Date of Patent: October 23, 2018Assignee: SciFluor Life Sciences, Inc.Inventors: Ben C. Askew, Richard W. Heidebrecht, Takeru Furuya, Mark E. Duggan, D. Scott Edwards
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Patent number: 9895340Abstract: The invention relates to fluorinated compounds and their use in the field of pathological syndromes of the cardiovascular system. Novel fluorinated benzofuran derivatives of amiodarone and pharmaceutically acceptable salts or solvates thereof and their use for the treatment of arrhythmias are described.Type: GrantFiled: March 10, 2017Date of Patent: February 20, 2018Assignee: SciFluor Life Sciences, Inc.Inventors: Mark E. Duggan, Takeru Furuya, D. Scott Edwards
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Patent number: 9802933Abstract: The invention relates to fluorinated compounds and their use as integrin receptor antagonists. Novel fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives and pharmaceutically acceptable salts or solvates thereof and their use are described.Type: GrantFiled: December 15, 2016Date of Patent: October 31, 2017Assignee: SciFluor Life Sciences, Inc.Inventors: Ben C. Askew, Richard W. Heidebrecht, Takeru Furuya, Mark E. Duggan
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Patent number: 9790222Abstract: The present invention relates to fluorinated compounds of formula I and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing the fluorinated compounds of the invention, and methods of treating fibrosis, macular degeneration, diabetic retinopathy (DR), macular edema, diabetic macular edema (DME), and macular edema following retinal vein occlusion (RVO), by administering these compounds and pharmaceutical compositions to subjects in need thereof.Type: GrantFiled: February 19, 2016Date of Patent: October 17, 2017Assignee: SciFluor Life Sciences, Inc.Inventors: Ben C. Askew, Takeru Furuya
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Patent number: 9717729Abstract: The present invention relates to fluorinated compounds of formula I and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing the fluorinated compounds of the invention, and methods of treating macular degeneration, diabetic retinopathy (DR), macular edema, diabetic macular edema (DME), and macular edema following retinal vein occlusion (RVO), by administering these compounds and pharmaceutical compositions to subjects in need thereof.Type: GrantFiled: November 4, 2016Date of Patent: August 1, 2017Assignee: SciFluor Life Sciences, Inc.Inventors: Ben C. Askew, Richard W. Heidebrecht, Takeru Furuya, Mark E. Duggan, D. Scott Edwards
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Patent number: 9662331Abstract: The invention relates to novel quinazolinone compounds and their use as inhibitors of PI3 kinases, for example, PI3K?, for treating and/or preventing diseases, disorder, and conditions associated with modulating PI3 kinase activity. Novel 3 -aryl-2-((arylamino)methyl)quinazolin-4(3H)-one derivatives and pharmaceutically acceptable salts or solvates thereof and their use for the treatment or prevention of diseases, disorders, and conditions associated with the activity of one or more PI3 kinase, such as PI3K?, are disclosed.Type: GrantFiled: November 13, 2015Date of Patent: May 30, 2017Assignee: SciFluor Life Sciences, Inc.Inventors: Ben C. Askew, Takeru Furuya
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Patent number: 9624169Abstract: The application relates to novel compounds and their use in treating and preventing diseases and conditions mediated by modulation of voltage-gated sodium channels. Novel aryl- and heteroaryl-pyrrolidine-2-carboxamide compounds and pharmaceutically acceptable salts or solvates thereof and their use are described.Type: GrantFiled: March 25, 2016Date of Patent: April 18, 2017Assignee: SciFluor Life Sciences, Inc.Inventors: Ben C. Askew, Takeru Furuya
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Patent number: 9624189Abstract: The invention relates to fluorinated compounds and their use in the field of pathological syndromes of the cardiovascular system. Novel fluorinated benzofuran derivatives of amiodarone and pharmaceutically acceptable salts or solvates thereof and their use for the treatment of arrhythmias are described.Type: GrantFiled: March 12, 2013Date of Patent: April 18, 2017Assignee: SciFluor Life Sciences, Inc.Inventors: Mark E. Duggan, Takeru Furuya, D. Scott Edwards
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Patent number: 9593114Abstract: The invention relates to fluorinated compounds and their use as integrin receptor antagonists. Novel fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives and pharmaceutically acceptable salts or solvates thereof and their use are described.Type: GrantFiled: January 19, 2016Date of Patent: March 14, 2017Assignee: SciFluor Life Sciences, Inc.Inventors: Ben C. Askew, Richard W. Heidebrecht, Takeru Furuya, Mark E. Duggan
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Patent number: 9572801Abstract: The present application relates to use of compounds of formula I for treating or preventing a fibrosis.Type: GrantFiled: April 29, 2016Date of Patent: February 21, 2017Assignee: SciFluor Life Sciences, Inc.Inventors: Ben C. Askew, D. Scott Edwards
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Patent number: 9556114Abstract: The invention relates to fluorinated compounds and their use as anti-epileptic, muscle-relaxing, fever-reducing and peripherally analgesically acting medications and as imaging agents. Novel fluorinated 2-amino-4-(benzylamino)phenyl carbamate derivatives of ezogabine and pharmaceutically acceptable salts or solvates thereof and their use are described.Type: GrantFiled: December 10, 2014Date of Patent: January 31, 2017Assignee: SciFluor Life Sciences, Inc.Inventors: Mark E. Duggan, Takeru Furuya, D. Scott Edwards, Ajay Purohit
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Patent number: 9518053Abstract: The present invention relates to fluorinated compounds of formula I and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing the fluorinated compounds of the invention, and methods of treating macular degeneration, diabetic retinopathy (DR), macular edema, diabetic macular edema (DME), and macular edema following retinal vein occlusion (RVO), by administering these compounds and pharmaceutical compositions to subjects in need thereof.Type: GrantFiled: February 7, 2014Date of Patent: December 13, 2016Assignee: SciFluor Life Sciences, Inc.Inventors: Ben C. Askew, Richard W. Heidebrecht, Takeru Furuya, Mark E. Duggan, D. Scott Edwards
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Patent number: 9266884Abstract: The invention relates to fluorinated compounds and their use as integrin receptor antagonists. Novel fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives and pharmaceutically acceptable salts or solvates thereof and their use are described.Type: GrantFiled: November 5, 2014Date of Patent: February 23, 2016Assignee: SciFluor Life Sciences, Inc.Inventors: Ben C. Askew, Richard W. Heidebrecht, Takeru Furuya, Mark E. Duggan