Abstract: The present invention relates to cinnamic acid dimers, their preparation and the use thereof for treating neurodegenerative disease, which have excellent effect on enhancing the learning and memory-retention ability in vivo and have fewer side-effects by showing no hormone properties, even when administered for a long period of time, and thus which can be used for neurodegenerative disease including dementia.
Type:
Grant
Filed:
June 25, 2002
Date of Patent:
September 21, 2010
Assignees:
Korea Institute of Science and Technology, Scigenic Co., Ltd.
Inventors:
Dong-Jin Kim, Kye-Jung Shin, Jaehoon Yu, Hee-Sul Lee