Abstract: Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The medical device can include a composite cover formed of a deposited metallic film and one or more polymer layers. The polymer layers contribute to mechanical or biological properties of the endoprosthesis.

Abstract: Medical device delivery systems, and related methods and components, are disclosed. In some embodiments, an implantable medical endoprosthesis delivery system includes a catheter, a sheath at least partially surrounding the catheter, and a tip coupled to a distal end portion of the catheter. The tip can cooperate with a distal end surface of the sheath to form a gap therebetween so that there is fluid communication between an interior region of the sheath and an exterior region of the sheath.

Abstract: Coils, such as embolic coils, and related methods, devices, and compositions, are disclosed.

Abstract: An ablation device includes a cannula having a lumen, a first array of electrodes deployable from within the lumen, and a second array of electrodes deployable from within the lumen, wherein the first array of electrodes has a configuration that is different from a configuration of the second array of electrodes.

Abstract: Anchoring mechanisms for releasably securing an intravascular device along an elongated member such as a guidewire or catheter. The anchoring mechanism may include an object that can be actuated between an unlocked position and a locked position. In the unlocked position, the anchoring mechanism is slidably and rotationally disposed about the elongated member. In the locked position, the anchoring mechanism is releasably secured to the elongated member, preventing movement thereon. A placement mechanism such as a tubular member can be utilized to actuate the anchoring mechanism between the unlocked and locked positions.

Abstract: An apparatus and method for ejecting fluid from a fluid delivery system. The fluid delivery system has a pneumatic assembly that when triggered injects gas into a hydraulic assembly, which in turn ejects fluid through an external interface. An electronic interface displays various measurements, for example, how much fluid has been ejected and if the hydraulic system is closed the pressure of the system. The pneumatic assembly can also be depressurized such that fluid can reenter the hydraulic assembly through the external interface.

Abstract: Apparatus for measuring an amount of ablation fluid circulating in a system for ablating tissue comprises a plurality of electrical contacts located within an ablation fluid receiving chamber of the system, the contacts being located at various heights and a data processing arrangement coupled to the contacts to receive data corresponding to electrical conductance between pairs of the contacts, the data processing arrangement determining a height of fluid in the chamber based on the measured conductance levels and determining based on the determined height, whether an amount of fluid circulating through the system is within a desired range.

Abstract: A covered stent comprises a coiled sheet stent having at least a portion with open cell geometry and a graft material covering at least a portion of the coiled sheet stent.

Abstract: A system for placing an implant in the body includes an elongated member having at least one inner lumen extending from a proximal end portion of the member to an opening in a distal end portion of the member. At least one compressible implant is in the inner lumen of the member. The implant optionally includes anchor members projecting from its outer surface to limit migration of the implant in the body. Structure is provided to push the implant through the opening in the distal end of the member. The implant is placed between layers of body tissue to bulk the tissue. In one of the disclosed methods, the system is used to treat gastroesophageal reflux disease (GERD) by placing the implant between layers of body tissue at or near the gastroesophageal junction.

Abstract: A method for ablating tissue comprising controlling a heating element using a variable phase angle control to heat an ablation fluid to a desired temperature and determining a heating percentage corresponding to a percentage of a maximum available heating power represented by a current level of power supplied to the heating element and, when the heating percentage remains below a threshold level for a predetermined period of time, indicating a flow obstruction condition of the fluid.

Abstract: The invention relates generally to a medical device for delivering a therapeutic agent to the body tissue of a patient, and methods for making such a medical device. More particularly, the invention is directed to a stent, such as an intravascular stent, having an inner and outer coating compositions disposed thereon. In another embodiment, the inner coating composition and outer coating composition are separated by a barrier coating composition.

Abstract: The present invention is directed to methods and systems for aligning and coating a medical device during a single coating cycle. A first section of an applicator may apply a contact force to surfaces of the medical device. The contact force may align and remove surface irregularities from the medical device prior to coating the medical device with coating. The coating may be resident on a second section of the applicator.

Abstract: A snare device and methods of making and using the same. The snare device may include a sheath having a proximal end region, a distal end region, and a shaft slidably disposed therein. A handle may be coupled to the shaft and disposed adjacent the proximal end region. The snare device may also include a swivel disposed adjacent the distal end region of the sheath and coupled to the shaft and to a snare loop.

Abstract: A medical device includes an elongate member having a plurality of flexibility features and a basket having a plurality of legs. The elongate member and the basket are formed from a single piece of a material. The flexibility features are formed by removing first portions of the material to increase flexibility of the elongate member. The legs are formed by removing longitudinal portions of the material.

Abstract: A tissue ablation device comprises first and second electrodes of opposite polarities, the first electrode being mounted to a first elongated member for movement relative to the second electrode for separation therefrom by a desired distance. A method of ablating a tissue comprises inserting first and second electrodes to desired initial positions relative to a tissue mass to be ablated and applying electrical energy to the first and second electrodes to ablate a first portion of tissue between the first and second electrodes in combination with the step of applying electrical energy to desired second positions separated from the desired initial positions by a distance selected to transfer electrical energy around the first portion of tissue through a second portion of tissue to be ablated, the second portion of tissue surrounding the first portion of tissue.

Abstract: In one embodiment of the invention, a stent may be provided comprising a first undulating band having alternating peaks and troughs, a second undulating band having alternating peaks and troughs, a first substantially longitudinal connector extending between the first and second undulating bands and a second very short connector extending between the first and second undulating bands, the first connector substantially longer than the second very short connector.

Abstract: An integrated catheter assembly for enabling diverse endoscopic in situ therapies. The assembly includes a catheter with an irrigation fluid lumen, a distal electrode tip portion that acts as a hemostat, and a cutting wire for making incisions in or ablating tissue. A cutting wire hub provides a sealing entrance for a cutting wire. An operator enables the physician to displace the cutting wire between extended and retracted positions. The cutting wire and electrode are electrically isolated. In addition, the catheter assembly may include a planar tip which, when extended outside the distal end of the assembly, assumes a substantially flat unbiased configuration for use. The apparatus of the present invention allows the physician to make incisions in or ablate tissue using electrosurgery, irrigate tissue, and cauterize or coagulate tissue without having to remove the apparatus from the working channel of the endoscope.

Abstract: A porous weave of bioabsorbable filaments having an open mesh configuration is formed into an oblate shape having dimensions greater than the esophageal opening and gastric outlet of a stomach. The resulting prosthesis is deployed in the stomach and is of a size to be retained in the proximate portion thereof for exerting pressure on the upper fundus. The prosthesis limits the amount of food that may be held within the stomach, and exerts pressure on the fundus to create a sensation of being full, resulting in weight loss.

Abstract: A catheter for carotid artery dilatation that includes a multi-chamber balloon assembly mounted at the distal end of the elongated tube that has at least two tandem chambers. Each chamber communicates with a separate lumen and each separate lumen terminates at the proximal end at a lumen valve head. The chambers have an inflated configuration with a diameter that progressively tapers in a direction from proximal to distal, said taper extends substantially continuously from the proximal end of the balloon assembly to the distal end thereof.

Abstract: An anti-reflux ureteral stent includes an elongated member with a distal end having a first retention structure and a proximal end having a second retention structure. A lumen extends between the distal and proximal ends. The elongated member may include a valve near the proximal end and distal to the second retention structure. The valve may include one or more slits or windows tending to render the elongated member collapsible. The valve may include one or more protrusions to partially occlude the lumen. A protrusion, if present, may be shaped as a helical thread. The second retention structure may be shaped as a barb to engage a ureteral orifice in a bladder.