Abstract: Example cardiac pump systems are disclosed. An example cardiac pump system includes a cardiac pump coupled to a console. Further, the console includes a first display including a first visual representation of a first parameter of the cardiac pump system. Further, the first display includes a first status indicator and a second status indicator corresponding to the first parameter. Further, the first display is configured to display the first status indicator when the first parameter satisfies a first condition, and wherein the first display is configured to display the second status indicator when the first parameter satisfies a second condition.

Abstract: A medical device for delivering energy and/or fluid includes a handle, a shaft extending distally from the handle, a fluid port configured to deliver fluid through at least a portion of the shaft, and an end effector at a distal end of the shaft. The handle includes a hub for electrically connecting the medical device to an energy source. The shaft includes an outer sheath, an inner sheath, and a control wire. The end effector includes a loop portion and an electrode coupled to a distal end of the loop portion. A proximal end of the loop portion is coupled to a distal end of the control wire such that movement of the control wire controls a position of the end effector relative to the distal end of the shaft.

Abstract: A method of generating a color image using a monochromatic image sensor. The method includes sequentially illuminating a surface in a plurality of colors, one color at a time. The monochromatic image sensor captures a plurality of image frames of the surface based on the plurality of colors. The plurality of image frames are identified, and at least one feature in the target of the plurality of image frames is highlighted. Color intensities of the plurality of image frames are normalized. A color intensity map of the target for each of the plurality of image frames is generated. A correlation score is determined by comparing each color intensity map of the plurality of image frames. The color image is generated based on the correlation score.

Abstract: A stent delivery system including an elongate shaft of a medical device, a stent selectively coupled to a distal portion of the elongate shaft, and a coupling mechanism for selectively coupling the stent to the elongate shaft by inserting a tab on one of the stent or the elongate shaft into an opening in the other of the stent or the elongate shaft. The tab may be deflected from a first position to a second position to disengage the tab from the opening.

Abstract: A medical device may include a handle and a flexible sheath extending from the handle. The sheath may include a first chamber configured to receive a first agent and a second chamber configured to receive a second agent. Each of the first chamber and the second chamber may be disposed in a distal portion of the sheath. The sheath may also include a first piston received within the first chamber and a second piston received within the second chamber and at least one actuation element configured to transmit a force from the handle to each of the first piston and the second piston. In a first configuration, the first agent may be maintained within the first chamber and the second agent is maintained within the second chamber. In a second configuration, the first agent may be released from the first chamber to mix with the second agent.

Abstract: This disclosure relates generally to medical tubing assemblies and methods for fluid delivery from a single fluid reservoir. In one example, a tubing assembly may be configured to couple to an endoscope for distributing fluid between the endoscope and a fluid reservoir during an endoscopic procedure. The assembly may comprise a tubing manifold, a cap configured to be removably attached to the fluid reservoir, a portion of gas supply tubing and lens wash supply tubing in fluid communication between the manifold and the endoscope, a portion of gas supply tubing in fluid communication between the cap and the manifold, and a portion of lens wash supply tubing in fluid communication between the fluid reservoir and the manifold. Further examples may include portions of irrigation supply tubing and portions of alternate gas supply tubing selectively connectable in fluid communication between the manifold, fluid reservoir and endoscope.

Abstract: Embodiments herein relate to a method for treating a cancerous tumor located within a subject. The method can include applying one or more electric fields at or near a site of the cancerous tumor, where the cancerous tumor can include a cancerous cell population. The one or more applied electric fields are effective to delay mitosis and cause mitotic synchronization within a proportion of the cancerous cell population. The method can include removing the one or more electric fields to allow mitosis to proceed within the cancerous cell population. The method can include administering a chemotherapeutic agent to the subject after the one or more electric fields have been removed. Other embodiments are also included herein.

Abstract: Intravascular imaging systems and methods for making and using intravascular imaging devices are disclosed. An example intravascular imaging device may include an imaging catheter. An imaging core may be translatable and rotatable within the imaging catheter. The imaging core may include a first imaging device and a second imaging device different from the first imaging device. A connector assembly may be disposed adjacent to a proximal end region of the imaging catheter. The connector assembly may be configured to connect the imaging catheter to a control unit. The connector assembly may include a first connector for connecting the first imaging device to the control unit and a second connector for connecting the second imaging device to the control unit. The connector assembly may be spring-loaded.

Abstract: A deployment system includes a sheath, a shaft having a handle positioned at its proximal end, a micro motor having a motor shaft at the shafts distal end, a detachable helical first suture anchor positioned at the motor shafts distal end and an elongate suture fixedly coupled to the suture anchor. The deployment system can be positioned at a first tissue, and the motor shaft rotated to advance the helical first suture anchor into engagement with the first tissue. The motor shaft is detached from the first suture anchor thereby deploying it at the first tissue location. The deployment system can be reloaded with multiple suture anchors to deploy at multiple tissue locations. The suture extending between the anchors can then be drawn together to reconfigure the coupled tissue.

Abstract: A sheath with an expandable and reducible diameter includes a body having a lumen and that is movable between a first configuration and a second configuration. The body has a first diameter size in the first configuration that is smaller than a second diameter size in the second configuration. The body includes a shaft made from a first material and a wire made from a second material.

Abstract: A percutaneous circulatory support system includes an impeller and a motor operably coupled to the impeller. A controller is operably coupled to the motor, and the controller is configured to: drive the motor, the motor thereby rotating the impeller to cause blood to flow; determine that an operating parameter of the system deviates from a symmetric waveform; and in response to determining that the operating parameter deviates from the symmetric waveform, provide an alert of aortic valve insufficiency.

Abstract: A percutaneous circulatory support device includes a housing having a proximal end portion, a distal end portion, and a longitudinal axis extending between the proximal end portion and the distal end portion. An impeller is disposed within the housing, and the impeller is configured to rotate relative to the housing to cause blood to flow through the housing. A motor is operably coupled to the impeller, and the motor is configured to rotate the impeller relative to the housing. A pressure sensor is coupled to the housing and is disposed at a non-zero angle relative to the longitudinal axis.

Abstract: A percutaneous circulatory support system includes a percutaneous circulatory support device having an impeller and a distal portion. A guidewire insertion aide is removably carried in the distal portion of the percutaneous circulatory support device. The guidewire insertion aide includes a tapered distal end portion initially in contact with the distal portion of the percutaneous circulatory support device. The guidewire insertion aide is configured to couple to a guidewire.

Abstract: A medical device includes a shaft, an end effector at a distal end of the shaft, the end effector having a first jaw that pivots relative to a second jaw about a pivot axis, a control mechanism engaging a surface of the first jaw, such that when the control mechanism translates relative to the pivot axis from a first state to a second state, the surface of the first jaw moves relative to the control mechanism and pivot about the pivot axis. The medical device further includes an actuator extending through the shaft and coupled to the control mechanism, where translation of the actuator translates the control mechanism from the first state to the second state.

Abstract: A percutaneous circulatory support device includes an impeller housing configured to receive a guidewire during delivery of the percutaneous circulatory support device to a patient. A catheter is coupled to a proximal end portion of the impeller housing, the catheter including a lumen being configured to receive the guidewire during delivery of the percutaneous circulatory support device to the patient. An impeller is rotatable in the impeller housing after delivery of the percutaneous circulatory support device to the patient to cause blood to flow through the percutaneous circulatory support device.

Abstract: Aqueous liquid embolic compositions, for example formed from amino acids, as well as method for making and using aqueous liquid embolic compositions are disclosed. An example aqueous liquid embolic composition may include a di-block or tri-block copolymer including a charged block and a hydrophobic block. The aqueous liquid embolic composition may also include templating agent.

Abstract: Aqueous liquid embolic compositions as well as method for making and using aqueous liquid embolic compositions are disclosed. An example aqueous liquid embolic composition may include a di-block or tri-block copolymer including a hydrophobic monomer block and a charged (polycationic or polyanionic) block. The charged (polycationic or polyanionic) block may include one or more anions. The aqueous liquid embolic composition may also include templating agent.

Abstract: Metabolic disorders such as Type 2 diabetes may be treated using a system that is adapted to modulate an hepatic neural plexus of a patient. The system includes a stimulation device adapted for implantation near the patient's hepatic neural plexus and to provide mechanical energy to the patient's hepatic neural plexus, a source of excitation energy adapted to provide excitation energy to the stimulation device, and a controller that is operably coupled to the source of excitation energy and is adapted to control the source of excitation energy.

Abstract: The present disclosure relates to the field of tissue dissection. Specifically, the present disclosure relates to medical devices that lift and retract tissue during a dissection procedure to improve visualization of the target tissue and mitigate obstructions for dissection tools. In particular, the present disclosure relates to devices that transition from a constrained to an unconstrained bowed configuration to immobilize and retract the dissected portion of target tissue during a dissection procedure.

Abstract: The present disclosure provides apparatus and methods to generate a three-dimensional (3D) model of the physiology of a vessel from a single angiographic image and a series of intravascular images as well as another physical characteristic of the vessel, such as, for example, pressure.