Abstract: A mitral valve leaflet repair system may include a delivery catheter having at least one lumen extending proximally from a distal end of the delivery catheter, a plurality of anchor elements disposed within the at least one lumen, each of the plurality of anchor elements being configured to extend through one layer of mitral valve leaflet tissue, and a securing element configured to secure at least two of the plurality of anchor elements together on one side of the mitral valve leaflet tissue. The at least one lumen may include a suction lumen configured to grasp a mitral valve leaflet prior to extending the plurality of anchor elements through one layer of mitral valve leaflet tissue.

Abstract: An endoscopic device has a handle including an adapter, a shaft connected to the handle, and one or more wires within the handle. The adapter defines one or more openings in a side or proximal end of the adapter. The shaft has a plurality of lumens extending from a proximal end of the shaft to a distal end of the shaft. A first lumen of the plurality of lumens is a working channel for receiving a medical instrument. Each of the one or more wires enter through the one or more openings in the adapter for guiding the one or more wires to a corresponding lumen other than the first lumen and to the distal end of the shaft.

Abstract: A medical device comprising an enclosure defining a cavity for containing agent, a lumen for receiving a pressurized gas, and a barrier positioned between the cavity and the lumen, the barrier including at least one opening for storing agent, wherein rotation of the barrier relative to the lumen establishes fluid communication between the at least one opening and the lumen for delivering agent from the at least one opening to the lumen.

Abstract: An endoscopic deployment device includes a body mountable on an endoscopic device, a communication interface, and a motor. The body has a movable carrier couplable to an elongated end effector device. The effector device has an end effector shaft covered by an outer sheath and an end effector extending from a distal end of the shaft. The sheath is sized and shaped for insertion through a working channel of an endoscopic shaft of the endoscopic device. The body has a carrier channel sized for the carrier to slide therein. The end effecter is actuatable between open and closed positions by sliding the carrier in the carrier channel which in turn slides the sheath over the end effector shaft to uncover/cover the end effector. Rotation of a drive shaft of the motor is sliding the carrier in the carrier channel and actuating the end effector in response to a signal.

Abstract: Various aspects of the present disclosure may be directed toward apparatuses, systems, and methods that include a medical device including an elongate body having a proximal portion, a distal portion, and three mutually perpendicular planes. The medical device may include a first steering line and a second steering line and a first stiffening material and a second stiffening material. The first stiffening material and the second stiffening material may be configured to maintain planarity of deflection of at least the distal portion of the elongate body.

Abstract: The invention provides, in various embodiments, aspects of soft tissue anchors, adjustable length/tension slings, interconnects between slings and soft tissue anchors, delivery devices and systems for implanting supportive slings, and methods relating to anchoring, 5 adjusting and implanting supportive slings.

Abstract: A method for coupling a first medical device component to a second medical device component comprising altering the first medical device component from a natural state to an altered state, by reducing a cross-sectional dimension of the first medical device, fitting a first portion of the first medical device component in the altered state into a first opening of the second medical device component, wherein the first medical device component includes second portions not within the first opening of the second medical device component, and allowing the second portions of the first medical device component to revert back to the natural state.

Abstract: Methods and systems for supplying gas and water to an endoscope system. An illustrative container and tube set may comprise a container configured to contain a fluid and having a bottom portion and a top portion, a lens water supply tube including a first end, a second end, and a first lumen extending therethrough, a gas supply tube including a first end, a second end, and a second lumen extending therethrough, a port positioned adjacent to the top portion of the container, and a flexible tube including a first end coupled to the top portion of the container, a second end, and a third lumen extending therethrough. The third lumen of the flexible tube may be configured to be in selective fluid communication with the interior of the container.

Abstract: The present disclosure relates generally to the field of medical devices and medical device accessories. In particular, the present disclosure relates to a tool or accessory for cleaning a medical device. For example, the tool or accessory may clean a fluid delivery lumen of an endoscopic submucosal dissection (ESD) knife. The tool or accessory may include a housing with a first portion of an elongate member secured within a first portion of the housing and a second portion of the elongate member extending into a chamber of the housing.

Abstract: A cannulation device is adapted to gain access to the patient's common bile duct. In some instances, the cannulation device includes a first guidewire lumen extending through an elongate shaft and terminating at a first oblique guidewire port, and a second guidewire lumen extending through the elongate shaft and terminating at a second oblique guidewire port. In some instances, the cannulation device includes an inflatable balloon that is inflatable from a collapsed configuration to an expanded configuration in which the inflatable balloon is adapted to occlude the patient's pancreatic duct. In some instances, the cannulation device includes an expandable element that is expandable from a collapsed configuration in which the expandable element is disposed within the guidewire lumen and an extended configuration in which a portion of the expandable element extends distally from a guidewire port.

Abstract: Methods and systems for coupling gas and water supply tubes to a container. An illustrative container and tube set may comprise a container configured to contain a fluid, the container having a bottom portion and a top portion, a water supply tube including a first end, a second end, and a first lumen, a gas supply tube including a first end, a second end, and a second lumen, and a weight coupled to the first end of the water supply tube and a first end of the gas supply tube. The first lumen may be in selective fluid communication with the bottom portion of the container and the second end of the water supply tube positioned external to the container. The second lumen may be in operative fluid communication with the container and the second end of the gas supply tube is positioned external to the container.

Abstract: A system includes a medical device and computer-readable media storing instructions that, when executed by a processor, cause operations to be performed, including: receiving a three-dimensional (3D) image of anatomy, processing the 3D image to extract a 3D model identifying anatomical structures of interest, receiving images captured by an imaging device of the medical device as the medical device is navigated through a body lumen to a target site, including a current image of the target site, receiving medical device spatial information from a position sensing system including a transmitter/receiver in or on the medical device, processing the images and spatial information to generate a 3D surface map of the body lumen, registering the 3D model to the patient using the map and spatial information, and generating and displaying a graphical user interface overlaying a representation of a position/trajectory of the anatomical structures of interest on the current image.

Abstract: Laser systems and methods are disclosed. One laser system comprises: a plurality of laser resonators, each resonator being operable to discharge an input laser beam; a relay assembly including at least one curved reflective surface that redirects each input laser beam, and reduces a beam size of the redirected beam; a galvo including a curved reflective surface that receives each redirected beam, and outputs a combined laser beam at power level greater than a power level of each laser input beam; and a coupling assembly that reduces spherical aberrations in the combined laser beam, and directs the combined laser beam into an optical fiber. In this system, the combined laser beam may have a maximum beam parameter product lower than a minimum beam parameter product of the optical fiber. Related systems and methods are also disclosed.

Abstract: A system for containing and transporting a medical device may include a container including a bottom face and surrounding side faces as a closed first end and an open second end to form an inner portion for receiving and retaining the medical device. At least a portion of one or more of the side faces may have an indentation extending along a length of the respective side face. A liner and cover may be removably enclosable about the container. The liner may be extendable over the side faces to line the inner portion of the container. The cover may enclose the medical device in the container between the liner and cover. The indentation may be formed into the inner portion of the container. The container may be compatibly receivable in a first transportation device in a first orientation.

Abstract: A catheter system for imparting pressure to induce fractures at a treatment site within or adjacent a blood vessel wall includes a catheter, a fortified balloon inflation fluid and a first light guide. The catheter includes an elongate shaft and a balloon that is coupled to the elongate shaft. The balloon has a balloon wall and can expand to a first expanded configuration to anchor the catheter in position relative. The fortified balloon inflation fluid can expand the balloon to the first expanded configuration. The fortified balloon inflation fluid includes a base inflation fluid and a fortification component. The fortification component reduces a threshold for inducing plasma formation in the fortified balloon inflation fluid compared to the base inflation fluid. The fortification component can include at least one of carbon and iron. The first light guide is disposed along the elongate shaft and is positioned at least partially within the balloon.

Abstract: Devices, systems, and methods for connecting tubes to an endoscope. A connector for connecting tubing, such as gas/lens wash tubing, to fluid ports of an endoscope may include a first end that couples with the tubing and a second end for engaging fluid ports of an endoscope. The connector may have a stabilizing component configured to facilitate securing the second end to the endoscope. In some cases, the connector may include a device coupling member configured to couple to the endoscope and a core structure adding stability to the device coupling member and configured to couple to the tubing. In some cases, the stabilizing component may include an actuator and a retention component that adjusts in response to actuation of the actuator.

Abstract: Balloon catheters are described, including a balloon catheter that includes an inflatable balloon and a braiding positioned on an exterior surface of the inflatable balloon. The inflatable balloon includes an intermediate portion, a distal waist, and a transition portion between the intermediate portion and the distal waist. At least a portion of the transition portion has a cone angle of at least 40 degrees. The braiding includes a plurality of threads, and a spacing between adjacent threads of the plurality of threads over the distal waist is smaller than a spacing between adjacent threads of the plurality of threads over the intermediate portion. A spacing between adjacent threads of the plurality of threads over the transition portion gradually transitions over the transition portion from the spacing between adjacent threads over the intermediate portion to the spacing between adjacent threads over the distal waist.

Abstract: Methods and systems for refilling a container during an endoscopic procedure. An illustrative reservoir may be placed in selective fluid communication with a water bottle. The water bottle may form a fluid tight seal with the reservoir to transfer water from the water bottle to the reservoir.

Abstract: A medical device comprises a handle including an actuator, a shaft extending distally from the handle, wherein the shaft includes a lumen, and a distal cap. The distal cap includes a body including a first channel, wherein the first channel is in communication with a distal portion of the lumen, a distal face including an opening, wherein the opening is a distal opening of the channel, and an expandable portion coupled to the body, wherein the expandable portion is configured to expand radially outwards from the body and to retract radially inwards towards the body from an expanded position. The expandable portion includes at least one light.

Abstract: A medical device includes a handle, including a movable body. The medical device also includes a shaft extending from the handle, and an electrode at a distal end of the shaft. Movement of the movable portion of the handle controls a position of the electrode relative to the distal end of the shaft. At least a portion of the shaft includes a braiding.